How to B(e)-1 important cell during Leishmania infection

Detalhes bibliográficos
Autor(a) principal: Cruz, Luan Firmino
Data de Publicação: 2020
Outros Autores: Ricardo, Debora Decote, Gomes, Daniel Claudio de Oliveira, Morrot, Alexandre, Lima, Celio Geraldo Freire de, Guedes, Herbert Leonel de Matos
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/42517
Resumo: Universidade Federal do Rio de Janeiro. Instituto de Biofísica Carlos Chagas Filho. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.
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spelling Cruz, Luan FirminoRicardo, Debora DecoteGomes, Daniel Claudio de OliveiraMorrot, AlexandreLima, Celio Geraldo Freire deGuedes, Herbert Leonel de Matos2020-08-03T20:10:07Z2020-08-03T20:10:07Z2020CRUZ, Luan Firmino et al. How to B(e)-1 important cell during Leishmania infection. Frontiers in Cellular and Infection Microbiology, v. 9, Article 424, p. 1-8, Jan. 2020.2235-2988https://www.arca.fiocruz.br/handle/icict/4251710.3389/fcimb.2019.00424engFrontiers MediaLeishmanioseBALB/XIDCélulas B-1CDPIL-10LeishmaniasisBALB/XIDB-1 cellsB-1CDP cellsIL-10How to B(e)-1 important cell during Leishmania infectioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal do Rio de Janeiro. Instituto de Biofísica Carlos Chagas Filho. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.Universidade Federal Rural do Rio de Janeiro. Instituto de Veterinária. Seropédica, RJ, Brasil.Universidade Federal do Espírito Santo. Núcleo de Doenças Infecciosas / Núcleo de Biotecnologia. Vitória, ES, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunopatologia. Rio de Janeiro, RJ, Brasil./ Universidade Federal do Rio de Janeiro. Faculdade de Medicina. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Biofísica Carlos Chagas Filho. Laboratório de Imunomodulação. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Biofísica Carlos Chagas Filho. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Núcleo Multidisciplinar de Pesquisa UFRJ—Xerém em Biologia (NUMPEX-BIO). J Campus Duque de Caxias Professor Geraldo Cidade. Duque de Caxias, RJ, Brasil.B-1 cells are an innate-like population of B lymphocytes that are subdivided into B-1a and B-1b distinguished by the presence or absence of CD5, respectively. B-1 cells can act as regulatory B cells, are able to present antigen and produce IL-10. Leishmaniasis in humans is a complex of diseases caused by parasites of the genus Leishmania. More than 20 species can infect humans, with each species causing the development of different immunological responses in the host. Susceptibility is usually related to the production of anti-inflammatory cytokines while the production of Th1 cytokines is indicative of resistance. However, few studies have attempted to evaluate the role of B-1 cells during either the in vivo infection or in vitro interaction with Leishmania parasites. In vivo studies were performed using XID mice model, BALB/Xid mice have a mutation in the Bruton’s tyrosine kinase, which is an important enzyme for developing B-1 and maturing B-2 lymphocytes leading to the presence of immature B-2 cells. Here, we compile these studies and assess the influence of B-1 cells on disease progression with different Leishmania species.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/42517/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALLuanFirminoCruz_AlexandreMorrot_etal_IOC_2020.pdfLuanFirminoCruz_AlexandreMorrot_etal_IOC_2020.pdfapplication/pdf1290372https://www.arca.fiocruz.br/bitstream/icict/42517/2/LuanFirminoCruz_AlexandreMorrot_etal_IOC_2020.pdf52276120d8202462561da916d76adb2aMD52TEXTLuanFirminoCruz_AlexandreMorrot_etal_IOC_2020.pdf.txtLuanFirminoCruz_AlexandreMorrot_etal_IOC_2020.pdf.txtExtracted texttext/plain34401https://www.arca.fiocruz.br/bitstream/icict/42517/3/LuanFirminoCruz_AlexandreMorrot_etal_IOC_2020.pdf.txt48e296f3760bc0f77a58e8859741ccf5MD53icict/425172022-06-24 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dc.title.pt_BR.fl_str_mv How to B(e)-1 important cell during Leishmania infection
title How to B(e)-1 important cell during Leishmania infection
spellingShingle How to B(e)-1 important cell during Leishmania infection
Cruz, Luan Firmino
Leishmaniose
BALB/XID
Células B-1CDP
IL-10
Leishmaniasis
BALB/XID
B-1 cells
B-1CDP cells
IL-10
title_short How to B(e)-1 important cell during Leishmania infection
title_full How to B(e)-1 important cell during Leishmania infection
title_fullStr How to B(e)-1 important cell during Leishmania infection
title_full_unstemmed How to B(e)-1 important cell during Leishmania infection
title_sort How to B(e)-1 important cell during Leishmania infection
author Cruz, Luan Firmino
author_facet Cruz, Luan Firmino
Ricardo, Debora Decote
Gomes, Daniel Claudio de Oliveira
Morrot, Alexandre
Lima, Celio Geraldo Freire de
Guedes, Herbert Leonel de Matos
author_role author
author2 Ricardo, Debora Decote
Gomes, Daniel Claudio de Oliveira
Morrot, Alexandre
Lima, Celio Geraldo Freire de
Guedes, Herbert Leonel de Matos
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Cruz, Luan Firmino
Ricardo, Debora Decote
Gomes, Daniel Claudio de Oliveira
Morrot, Alexandre
Lima, Celio Geraldo Freire de
Guedes, Herbert Leonel de Matos
dc.subject.other.pt_BR.fl_str_mv Leishmaniose
BALB/XID
Células B-1CDP
IL-10
topic Leishmaniose
BALB/XID
Células B-1CDP
IL-10
Leishmaniasis
BALB/XID
B-1 cells
B-1CDP cells
IL-10
dc.subject.en.pt_BR.fl_str_mv Leishmaniasis
BALB/XID
B-1 cells
B-1CDP cells
IL-10
description Universidade Federal do Rio de Janeiro. Instituto de Biofísica Carlos Chagas Filho. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório Interdisciplinar de Pesquisas Médicas. Rio de Janeiro, RJ, Brasil.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-08-03T20:10:07Z
dc.date.available.fl_str_mv 2020-08-03T20:10:07Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CRUZ, Luan Firmino et al. How to B(e)-1 important cell during Leishmania infection. Frontiers in Cellular and Infection Microbiology, v. 9, Article 424, p. 1-8, Jan. 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/42517
dc.identifier.issn.pt_BR.fl_str_mv 2235-2988
dc.identifier.doi.none.fl_str_mv 10.3389/fcimb.2019.00424
identifier_str_mv CRUZ, Luan Firmino et al. How to B(e)-1 important cell during Leishmania infection. Frontiers in Cellular and Infection Microbiology, v. 9, Article 424, p. 1-8, Jan. 2020.
2235-2988
10.3389/fcimb.2019.00424
url https://www.arca.fiocruz.br/handle/icict/42517
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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