Wolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virus

Detalhes bibliográficos
Autor(a) principal: Pereira, Thiago Nunes
Data de Publicação: 2018
Outros Autores: Rocha, Marcele Neves, Sucupira, Pedro Henrique Ferreira, Carvalho, Fabiano Duarte, Moreira, Luciano Andrade
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/27734
Resumo: Fundação Oswaldo Cruz. Instituto René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil.
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spelling Pereira, Thiago NunesRocha, Marcele NevesSucupira, Pedro Henrique FerreiraCarvalho, Fabiano DuarteMoreira, Luciano Andrade2018-07-31T14:04:24Z2018-07-31T14:04:24Z2018PEREIRA, Thiago Nunes et al. Wolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virus. Scientific Reports, v. 8, art. 6889, 20182045-2322https://www.arca.fiocruz.br/handle/icict/2773410.1038/s41598-018-25236-8engNature Publishing GroupWolbachiaDengueZikaChikungunyaWolbachiaDengueZikaChikungunyaWolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virusinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Instituto René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Instituto René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Instituto René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil.Fundação Oswaldo Cruz. Instituto René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil.Wolbachia, an intracellular endosymbiont present in up to 70% of all insect species, has been suggested as a sustainable strategy for the control of arboviruses such as Dengue, Zika and Chikungunya. As Mayaro virus outbreaks have also been reported in Latin American countries, the objective of this study was to evaluate the vector competence of Brazilian field-collected Ae. aegypti and the impact of Wolbachia (wMel strain) upon this virus. Our in vitro studies with Aag2 cells showed that Mayaro vírus can rapidly multiply, whereas in wMel-infected Aag2 cells, viral growth was significantly impaired. In addition, C6/36 cells seem to have alterations when infected by Mayaro virus. In vivo experiments showed that field-collected Ae. aegypti mosquitoes are highly permissive to Mayaro virus infection, and high viral prevalence was observed in the saliva. On the other hand, Wolbachia-harboring mosquitoes showed significantly impaired capability to transmit Mayaro virus. Our results suggest that the use of Wolbachia-harboring mosquitoes may represent an effective mechanism for the reduction of Mayaro virus transmission throughout Latin America.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/27734/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINAL1.pdf1.pdfapplication/pdf780951https://www.arca.fiocruz.br/bitstream/icict/27734/2/1.pdf049ffd2047c3d07b70030af86852076cMD52TEXT1.pdf.txt1.pdf.txtExtracted texttext/plain39982https://www.arca.fiocruz.br/bitstream/icict/27734/3/1.pdf.txt6466e1b53742a6075c3fc1b1abe9f6e3MD53icict/277342019-06-19 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dc.title.pt_BR.fl_str_mv Wolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virus
title Wolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virus
spellingShingle Wolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virus
Pereira, Thiago Nunes
Wolbachia
Dengue
Zika
Chikungunya
Wolbachia
Dengue
Zika
Chikungunya
title_short Wolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virus
title_full Wolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virus
title_fullStr Wolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virus
title_full_unstemmed Wolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virus
title_sort Wolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virus
author Pereira, Thiago Nunes
author_facet Pereira, Thiago Nunes
Rocha, Marcele Neves
Sucupira, Pedro Henrique Ferreira
Carvalho, Fabiano Duarte
Moreira, Luciano Andrade
author_role author
author2 Rocha, Marcele Neves
Sucupira, Pedro Henrique Ferreira
Carvalho, Fabiano Duarte
Moreira, Luciano Andrade
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Pereira, Thiago Nunes
Rocha, Marcele Neves
Sucupira, Pedro Henrique Ferreira
Carvalho, Fabiano Duarte
Moreira, Luciano Andrade
dc.subject.other.pt_BR.fl_str_mv Wolbachia
Dengue
Zika
Chikungunya
topic Wolbachia
Dengue
Zika
Chikungunya
Wolbachia
Dengue
Zika
Chikungunya
dc.subject.en.pt_BR.fl_str_mv Wolbachia
Dengue
Zika
Chikungunya
description Fundação Oswaldo Cruz. Instituto René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil.
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-07-31T14:04:24Z
dc.date.available.fl_str_mv 2018-07-31T14:04:24Z
dc.date.issued.fl_str_mv 2018
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv PEREIRA, Thiago Nunes et al. Wolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virus. Scientific Reports, v. 8, art. 6889, 2018
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/27734
dc.identifier.issn.pt_BR.fl_str_mv 2045-2322
dc.identifier.doi.none.fl_str_mv 10.1038/s41598-018-25236-8
identifier_str_mv PEREIRA, Thiago Nunes et al. Wolbachia significantly impacts the vector competence of Aedes aegypti for Mayaro virus. Scientific Reports, v. 8, art. 6889, 2018
2045-2322
10.1038/s41598-018-25236-8
url https://www.arca.fiocruz.br/handle/icict/27734
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Nature Publishing Group
publisher.none.fl_str_mv Nature Publishing Group
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
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