Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2017 |
| Outros Autores: | , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/23311 |
Resumo: | Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil/Harvard T. H. Chan School of Public Health. Department of Immunology and Infectious Diseases. Boston. MA, United States of America |
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Dutra, Heverton Leandro CarneiroRodrigues, Silvia LomeuMansur, Simone BrutmanOliveira, Sofia Pimenta deCaragata, Eric PearceMoreira, Luciano Andrade2017-11-22T17:05:54Z2017-11-22T17:05:54Z2017DUTRA, Heverton Leandro Carneiro et al. Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti. Scientific Reports, n. 7, Article number: 15687, 20172045-2322https://www.arca.fiocruz.br/handle/icict/2331110.1038/s41598-017-16045-6engSpringer NatureAedes aegyptiWolbachiadengueZika vírusAedes aegyptiWolbachiadengueZika vírusMosquito control programsDevelopment and physiological effects of an artificial diet for Wolbachia-infected Aedes aegyptiinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil/Harvard T. H. Chan School of Public Health. Department of Immunology and Infectious Diseases. Boston. MA, United States of AmericaFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil/Johns Hopkins Bloomberg School of Public Health. W. Harry Feinstone Department of Molecular Microbiology and Immunology Baltimore, Maryland, United States of AmericaFundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, BrazilThe endosymbiotic bacterium Wolbachia spreads rapidly through populations of Aedes aegypti mosquitoes, and strongly inhibits infection with key human pathogens including the dengue and Zika viruses. Mosquito control programs aimed at limiting transmission of these viruses are ongoing in multiple countries, yet there is a dearth of mass rearing infrastructure specific to Wolbachia-infected mosquitoes. One example is the lack of a blood meal substitute, which accounts for the Wolbachia-specific physiological changes in infected mosquitoes, that allows the bacterium to spread, and block viral infections. To that end, we have developed a blood meal substitute specifically for mosquitoes infected with the wMel Wolbachia strain. This diet, ADM, contains milk protein, and infant formula, dissolved in a mixture of bovine red blood cells and Aedes physiological saline, with ATP as a phagostimulant. Feeding with ADM leads to high levels of viable egg production, but also does not affect key Wolbachia parameters including, bacterial density, cytoplasmic incompatibility, or resistance to infection with Zika virus. ADM represents an effective substitute for human blood, which could potentially be used for the mass rearing of wMel-infected A. aegypti, and could easily be optimized in the future to improve performance.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/23311/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINALDevelopment and physiological.pdfDevelopment and physiological.pdfapplication/pdf6715299https://www.arca.fiocruz.br/bitstream/icict/23311/2/Development%20and%20physiological.pdf14ed92837b8238b7900c8b826eefae50MD52TEXTDevelopment and physiological.pdf.txtDevelopment and physiological.pdf.txtExtracted texttext/plain537https://www.arca.fiocruz.br/bitstream/icict/23311/3/Development%20and%20physiological.pdf.txt74f2bf641cb72d94e7c7dd895de8afceMD53icict/233112019-06-19 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| dc.title.pt_BR.fl_str_mv |
Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti |
| title |
Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti |
| spellingShingle |
Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti Dutra, Heverton Leandro Carneiro Aedes aegypti Wolbachia dengue Zika vírus Aedes aegypti Wolbachia dengue Zika vírus Mosquito control programs |
| title_short |
Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti |
| title_full |
Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti |
| title_fullStr |
Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti |
| title_full_unstemmed |
Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti |
| title_sort |
Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti |
| author |
Dutra, Heverton Leandro Carneiro |
| author_facet |
Dutra, Heverton Leandro Carneiro Rodrigues, Silvia Lomeu Mansur, Simone Brutman Oliveira, Sofia Pimenta de Caragata, Eric Pearce Moreira, Luciano Andrade |
| author_role |
author |
| author2 |
Rodrigues, Silvia Lomeu Mansur, Simone Brutman Oliveira, Sofia Pimenta de Caragata, Eric Pearce Moreira, Luciano Andrade |
| author2_role |
author author author author author |
| dc.contributor.author.fl_str_mv |
Dutra, Heverton Leandro Carneiro Rodrigues, Silvia Lomeu Mansur, Simone Brutman Oliveira, Sofia Pimenta de Caragata, Eric Pearce Moreira, Luciano Andrade |
| dc.subject.other.pt_BR.fl_str_mv |
Aedes aegypti Wolbachia dengue Zika vírus |
| topic |
Aedes aegypti Wolbachia dengue Zika vírus Aedes aegypti Wolbachia dengue Zika vírus Mosquito control programs |
| dc.subject.en.pt_BR.fl_str_mv |
Aedes aegypti Wolbachia dengue Zika vírus Mosquito control programs |
| description |
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Endossimbiontes e Interação Patógeno-Vetor. Belo Horizonte, MG, Brazil/Harvard T. H. Chan School of Public Health. Department of Immunology and Infectious Diseases. Boston. MA, United States of America |
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2017 |
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2017-11-22T17:05:54Z |
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2017-11-22T17:05:54Z |
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2017 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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DUTRA, Heverton Leandro Carneiro et al. Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti. Scientific Reports, n. 7, Article number: 15687, 2017 |
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https://www.arca.fiocruz.br/handle/icict/23311 |
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2045-2322 |
| dc.identifier.doi.none.fl_str_mv |
10.1038/s41598-017-16045-6 |
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DUTRA, Heverton Leandro Carneiro et al. Development and physiological effects of an artificial diet for Wolbachia-infected Aedes aegypti. Scientific Reports, n. 7, Article number: 15687, 2017 2045-2322 10.1038/s41598-017-16045-6 |
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Springer Nature |
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Springer Nature |
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