Interpretation and clinical correlation of serological tests in paracoccidioidomycosis

Detalhes bibliográficos
Autor(a) principal: Valle, A. C. F. do
Data de Publicação: 2000
Outros Autores: Costa, R. L. B., Helder, J. von, Monteiro, P. C. F., Muniz, M. M., Zancopé-Oliveira, R. M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1080/mmy.39.4.373.377
Texto Completo: https://www.arca.fiocruz.br/handle/icict/33516
Resumo: 2020-06-16
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spelling Valle, A. C. F. doCosta, R. L. B.Helder, J. vonMonteiro, P. C. F.Muniz, M. M.Zancopé-Oliveira, R. M.2019-06-16T03:46:49Z2019-06-16T03:46:49Z2000VALLE, A. C. F. do et al. Interpretation and clinical correlation of serological tests in paracoccidioidomycosis. Medical Mycology, v. 39, p. 373-377, 2001.1369-3786https://www.arca.fiocruz.br/handle/icict/3351610.1080/mmy.39.4.373.3771460-2709engOxford University PressInterpretation and clinical correlation of serological tests in paracoccidioidomycosisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article2020-06-16Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Departamento de Microbiologia, Imunologia e Parasitologia. Setor de Micologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Departamento de Microbiologia, Imunologia e Parasitologia. Setor de Micologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Departamento de Microbiologia, Imunologia e Parasitologia. Setor de Micologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Departamento de Microbiologia, Imunologia e Parasitologia. Setor de Micologia. Rio de Janeiro, RJ, Brasil.In order to correlate the ndings of two serological tests, double immunodiffusion (IDD) and immunoblotting (IB), with the clinical diagnosis and follow-up of paracoccidioidomycosis (PCM), 325 serum samples from PCM patients were tested at the beginning of speci c therapy and after its completion. Group I included 245 PCM patients at the onset of symptoms without treatment. In 221 cases (90¢2%) the IDD showed positive reactions and in 24 (9¢8%) the results were negative. Of the 24 IDD negative samples, 23 were investigated by IB and were positive. Group II included 80 PCM patients under follow-up after treatment. There were four cases of relapse in which the IDD and IB tests were positive (100%). Among the 76 cases with inactive mycotic infection, the IDD was negative in 71¢2% and positive in 28¢8%; the IB was positive in all cases (100%). The control group (Group III) included 27 samples from patients with other mycoses, tuberculosis and from healthy individuals. All showed negative IDD tests but positive reactions with IB, which could be abolished by serum dilutions without altering the PCM reactivity. Therefore, the utilization of the IB, an immunoenzymatic method for the diagnosis of PCM, raised the sensitivity to 100%.ImmunologyParacoccidioides brasiliensisParacoccidioidomycosisSerological testsinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/33516/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Valle_ACF_etal_INI_2001.pdfve_Valle_ACF_etal_INI_2001.pdfapplication/pdf173255https://www.arca.fiocruz.br/bitstream/icict/33516/2/ve_Valle_ACF_etal_INI_2001.pdf626ae75c27219dca28c3a2eb3ebc8cd8MD52TEXTve_Valle_ACF_etal_INI_2001.pdf.txtve_Valle_ACF_etal_INI_2001.pdf.txtExtracted texttext/plain20688https://www.arca.fiocruz.br/bitstream/icict/33516/3/ve_Valle_ACF_etal_INI_2001.pdf.txt86d04244e946559c757e4d021ae94983MD53icict/335162021-03-24 16:32:32.997oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:32Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Interpretation and clinical correlation of serological tests in paracoccidioidomycosis
title Interpretation and clinical correlation of serological tests in paracoccidioidomycosis
spellingShingle Interpretation and clinical correlation of serological tests in paracoccidioidomycosis
Valle, A. C. F. do
Immunology
Paracoccidioides brasiliensis
Paracoccidioidomycosis
Serological tests
title_short Interpretation and clinical correlation of serological tests in paracoccidioidomycosis
title_full Interpretation and clinical correlation of serological tests in paracoccidioidomycosis
title_fullStr Interpretation and clinical correlation of serological tests in paracoccidioidomycosis
title_full_unstemmed Interpretation and clinical correlation of serological tests in paracoccidioidomycosis
title_sort Interpretation and clinical correlation of serological tests in paracoccidioidomycosis
author Valle, A. C. F. do
author_facet Valle, A. C. F. do
Costa, R. L. B.
Helder, J. von
Monteiro, P. C. F.
Muniz, M. M.
Zancopé-Oliveira, R. M.
author_role author
author2 Costa, R. L. B.
Helder, J. von
Monteiro, P. C. F.
Muniz, M. M.
Zancopé-Oliveira, R. M.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Valle, A. C. F. do
Costa, R. L. B.
Helder, J. von
Monteiro, P. C. F.
Muniz, M. M.
Zancopé-Oliveira, R. M.
dc.subject.en.pt_BR.fl_str_mv Immunology
Paracoccidioides brasiliensis
Paracoccidioidomycosis
Serological tests
topic Immunology
Paracoccidioides brasiliensis
Paracoccidioidomycosis
Serological tests
description 2020-06-16
publishDate 2000
dc.date.issued.fl_str_mv 2000
dc.date.accessioned.fl_str_mv 2019-06-16T03:46:49Z
dc.date.available.fl_str_mv 2019-06-16T03:46:49Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv VALLE, A. C. F. do et al. Interpretation and clinical correlation of serological tests in paracoccidioidomycosis. Medical Mycology, v. 39, p. 373-377, 2001.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/33516
dc.identifier.issn.pt_BR.fl_str_mv 1369-3786
dc.identifier.doi.none.fl_str_mv 10.1080/mmy.39.4.373.377
dc.identifier.eissn.none.fl_str_mv 1460-2709
identifier_str_mv VALLE, A. C. F. do et al. Interpretation and clinical correlation of serological tests in paracoccidioidomycosis. Medical Mycology, v. 39, p. 373-377, 2001.
1369-3786
10.1080/mmy.39.4.373.377
1460-2709
url https://www.arca.fiocruz.br/handle/icict/33516
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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