The moderation of multimorbidity and depressive symptoms on cognition
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/55994 |
Resumo: | UK Biotechnology and Biological Sciences Research Council. UK Medical Research Council and the University of Cambridg. U.S. National Institute of Mental Health. UK Medical Research Council. |
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Araújo, Jacyra Azevedo Paiva deXavier, Érika Fialho MoraisRodrigues, Elisângela da SilvaMachado, Daiane BorgesBarreto, Marcos E.Kanaan, Richard A.Barreto, Mauricio L.Araújo, Luís Fernando Silva Castro de2022-12-16T12:20:11Z2022-12-16T12:20:11Z2022ARAÚJO, Jacyra Azevedo Paiva de et al. The moderation of multimorbidity and depressive symptoms on cognition. Brazilian Journal of Psychiatry, v. 44, n. 6, p. 1-13, 2022.1809-452Xhttps://www.arca.fiocruz.br/handle/icict/5599410.47626/1516-4446-2022-2601UK Biotechnology and Biological Sciences Research Council. UK Medical Research Council and the University of Cambridg. U.S. National Institute of Mental Health. UK Medical Research Council.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para a Saúde. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para a Saúde. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para a Saúde. Salvador, BA, Brasil / Universidade Federal do Ceará. Itapagé, CE, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para a Saúde. Salvador, BA, Brasil / Harvard Medical School. Department Global Health and Social Medicine. USA.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para a Saúde. Salvador, BA, Brasil / Department of Statistics. London School of Economics and Political Science. London, UK.Dept of Psychiatry. The University of Melbourne. Austin Health, Australia.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para a Saúde. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para a Saúde. Salvador, BA, Brasil / Dept of Psychiatry. The University of Melbourne. Austin Health, Australia.OBJECTIVE: Multimorbidity, or the occurrence of two or more chronic conditions, is a global challenge, with implications for mortality, morbidity, disability, and life quality. Psychiatric disorders are common among the chronic diseases that affect patients with multimorbidity. It is still not well understood whether psychiatric symptoms, especially depressive symptoms, moderate the effect of multimorbidity on cognition. METHODS: We used a large (n=2,681) dataset to assess whether depressive symptomatology moderates the effect of multimorbidity on cognition using structural equation modelling. RESULTS: It was found that the more depressive symptoms and chronic conditions, the worse the cognitive performance, and the higher the educational level, the better the cognitive performance. We found a significant but weak (0.009; p = 0.04) moderating effect. CONCLUSION: We have provided the first estimate of the moderating effect of depression on the relation between multimorbidity and cognition, which was small. Although this moderation has been implied by many previous studies, it was never previously estimated.engAssociação Brasileira de PsiquiatriaMultimorbidadeEpidemiologiaEnvelhecimentoModelagem de equações estruturaisMultimorbidityEpidemiologyAgingStructural equation modelingMultimorbidadeEpidemiologiaEnvelhecimentoAnálise de Classes LatentesThe moderation of multimorbidity and depressive symptoms on cognitioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/55994/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALAraujo, J. A. P.The moderation of multimorbidity and depressive symptoms on cognition.....pdfAraujo, J. A. P.The moderation of multimorbidity and depressive symptoms on cognition.....pdfapplication/pdf512909https://www.arca.fiocruz.br/bitstream/icict/55994/2/Araujo%2c%20J.%20A.%20P.The%20moderation%20of%20multimorbidity%20and%20depressive%20symptoms%20on%20cognition.....pdf3342ff8a0551f644474462bb5948e9a2MD52icict/559942023-03-15 14:32:49.12oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:32:49Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.en_US.fl_str_mv |
The moderation of multimorbidity and depressive symptoms on cognition |
| title |
The moderation of multimorbidity and depressive symptoms on cognition |
| spellingShingle |
The moderation of multimorbidity and depressive symptoms on cognition Araújo, Jacyra Azevedo Paiva de Multimorbidade Epidemiologia Envelhecimento Modelagem de equações estruturais Multimorbidity Epidemiology Aging Structural equation modeling Multimorbidade Epidemiologia Envelhecimento Análise de Classes Latentes |
| title_short |
The moderation of multimorbidity and depressive symptoms on cognition |
| title_full |
The moderation of multimorbidity and depressive symptoms on cognition |
| title_fullStr |
The moderation of multimorbidity and depressive symptoms on cognition |
| title_full_unstemmed |
The moderation of multimorbidity and depressive symptoms on cognition |
| title_sort |
The moderation of multimorbidity and depressive symptoms on cognition |
| author |
Araújo, Jacyra Azevedo Paiva de |
| author_facet |
Araújo, Jacyra Azevedo Paiva de Xavier, Érika Fialho Morais Rodrigues, Elisângela da Silva Machado, Daiane Borges Barreto, Marcos E. Kanaan, Richard A. Barreto, Mauricio L. Araújo, Luís Fernando Silva Castro de |
| author_role |
author |
| author2 |
Xavier, Érika Fialho Morais Rodrigues, Elisângela da Silva Machado, Daiane Borges Barreto, Marcos E. Kanaan, Richard A. Barreto, Mauricio L. Araújo, Luís Fernando Silva Castro de |
| author2_role |
author author author author author author author |
| dc.contributor.author.fl_str_mv |
Araújo, Jacyra Azevedo Paiva de Xavier, Érika Fialho Morais Rodrigues, Elisângela da Silva Machado, Daiane Borges Barreto, Marcos E. Kanaan, Richard A. Barreto, Mauricio L. Araújo, Luís Fernando Silva Castro de |
| dc.subject.other.en_US.fl_str_mv |
Multimorbidade Epidemiologia Envelhecimento Modelagem de equações estruturais |
| topic |
Multimorbidade Epidemiologia Envelhecimento Modelagem de equações estruturais Multimorbidity Epidemiology Aging Structural equation modeling Multimorbidade Epidemiologia Envelhecimento Análise de Classes Latentes |
| dc.subject.en.en_US.fl_str_mv |
Multimorbidity Epidemiology Aging Structural equation modeling |
| dc.subject.decs.en_US.fl_str_mv |
Multimorbidade Epidemiologia Envelhecimento Análise de Classes Latentes |
| description |
UK Biotechnology and Biological Sciences Research Council. UK Medical Research Council and the University of Cambridg. U.S. National Institute of Mental Health. UK Medical Research Council. |
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2022 |
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2022-12-16T12:20:11Z |
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2022-12-16T12:20:11Z |
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2022 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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ARAÚJO, Jacyra Azevedo Paiva de et al. The moderation of multimorbidity and depressive symptoms on cognition. Brazilian Journal of Psychiatry, v. 44, n. 6, p. 1-13, 2022. |
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https://www.arca.fiocruz.br/handle/icict/55994 |
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1809-452X |
| dc.identifier.doi.none.fl_str_mv |
10.47626/1516-4446-2022-2601 |
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ARAÚJO, Jacyra Azevedo Paiva de et al. The moderation of multimorbidity and depressive symptoms on cognition. Brazilian Journal of Psychiatry, v. 44, n. 6, p. 1-13, 2022. 1809-452X 10.47626/1516-4446-2022-2601 |
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Associação Brasileira de Psiquiatria |
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