HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics

Detalhes bibliográficos
Autor(a) principal: Fernandez, José Carlos Couto
Data de Publicação: 1999
Outros Autores: Morgado, Mariza Gonçalves, Bongertz, Vera, Tanuri, Amilcar, Andrade, Tarcisio Mattos de, Alves, Carlos Roberto Brites, Castro Filho, Bernardo Galvão
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/5646
Resumo: Fundação Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil
id CRUZ_aebcf1213e29f7c7bf9cbaaf785e412e
oai_identifier_str oai:www.arca.fiocruz.br:icict/5646
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Fernandez, José Carlos CoutoMorgado, Mariza GonçalvesBongertz, VeraTanuri, AmilcarAndrade, Tarcisio Mattos deAlves, Carlos Roberto BritesCastro Filho, Bernardo Galvão2012-10-04T20:34:19Z2012-10-04T20:34:19Z1999COUTO-FERNANDEZ, J.C. et al. HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics. Journal of Acquired Immune Deficience Syndromes v. 22, n. 3, p. 288-93, nov. 1999.1525-4135https://www.arca.fiocruz.br/handle/icict/5646engHIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristicsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, BrasilFundação Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, BrasilUniversidade Federal do Rio de Janeiro. Departamento de Genética. Rio de Janeiro, RJ, BrasilUniversidade Federal da Bahia. Centro de Tratamento do Abuso de Drogas. Salvador, BA, BrasilUniversidade Federal da Bahia. Laboratorio de Retrovirologia Prof. Edgard Santos Hospital. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilTo investigate the prevalence of the HIV-1 subtypes in different populations from Salvador, Bahia, Brazil, blood samples from 72 HIV-1-seropositive injecting drug users (IDUs) and 62 individuals infected sexually were analyzed using the heteroduplex mobility assay (HMA). In the IDU group, 89.5% were classified as subtype B, 3% as subtype F, and 7.5% showed a B/F HMA profile. In the sexual transmission (ST) group, 95% were identified as B subtype, 3.4% showed a B/F profile, and 1.6% a B/C/E HMA profile. All Brazilian samples that showed multiple reactivities in the HMA analysis clustered on sequencing with B North American/ European HIV-1 isolates in the phylogenetic analysis, whereas the F subtypes clustered with F Brazilian HIV-I isolates. Serologic reactivities of IDU's sera were examined using a panel of synthetic V3 loop peptides representative of the different HIV-1 subtypes. No difference in serologic reactivity between F and B subtype plasma could be observed. Predominance of HIV-I subtype B was identified in both study groups, whereas subtype F was detected only among IDUs in a frequency lower than described for other Brazilian regions.HIV-1SubtypesDiversityBrazilVariação AntigênicaInfecções por HIV/virologiaHIV-1/classificaçãoAdolescenteAdultoÁfrica/etnologiaGrupo com Ancestrais do Continente AfricanoBrasailEnsaio de Imunoadsorção EnzimáticaFemininoInfecções por HIV/imunologiaInfecções por HIV/transmissãoHIV-1/imunologiaAnálise HeteroduplexHumanosMasculinoMeia-IdadeFilogeniaReação em Cadeia da PolimeraseComportamento SexualFatores SocioeconômicosAbuso de Substâncias por Via Intravenosa/complicaçõesinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZORIGINALCouto-Fernandes HIV_1_Subtyping_in_Salvador,_Bahia,_Brazil__A_City.11[1].pdfCouto-Fernandes HIV_1_Subtyping_in_Salvador,_Bahia,_Brazil__A_City.11[1].pdfapplication/pdf4269771https://www.arca.fiocruz.br/bitstream/icict/5646/1/Couto-Fernandes%20HIV_1_Subtyping_in_Salvador%2c_Bahia%2c_Brazil__A_City.11%5b1%5d.pdfc4d52085f0cd1c6b1513fbae32f04c21MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82008https://www.arca.fiocruz.br/bitstream/icict/5646/2/license.txt06db3f0df647fd9ddff657403bbe0ee2MD52TEXTCouto-Fernandes HIV_1_Subtyping_in_Salvador,_Bahia,_Brazil__A_City.11[1].pdf.txtCouto-Fernandes HIV_1_Subtyping_in_Salvador,_Bahia,_Brazil__A_City.11[1].pdf.txtExtracted texttext/plain6https://www.arca.fiocruz.br/bitstream/icict/5646/5/Couto-Fernandes%20HIV_1_Subtyping_in_Salvador%2c_Bahia%2c_Brazil__A_City.11%5b1%5d.pdf.txt6d93d3216dc4a7f5df47d4876fbec4d3MD55THUMBNAILCouto-Fernandes HIV_1_Subtyping_in_Salvador,_Bahia,_Brazil__A_City.11[1].pdf.jpgCouto-Fernandes HIV_1_Subtyping_in_Salvador,_Bahia,_Brazil__A_City.11[1].pdf.jpgGenerated Thumbnailimage/jpeg1810https://www.arca.fiocruz.br/bitstream/icict/5646/4/Couto-Fernandes%20HIV_1_Subtyping_in_Salvador%2c_Bahia%2c_Brazil__A_City.11%5b1%5d.pdf.jpg6f1ebd4c8aeeff13725a72d7ca57c9e3MD54icict/56462023-03-15 14:32:59.927oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:32:59Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics
title HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics
spellingShingle HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics
Fernandez, José Carlos Couto
HIV-1
Subtypes
Diversity
Brazil
Variação Antigênica
Infecções por HIV/virologia
HIV-1/classificação
Adolescente
Adulto
África/etnologia
Grupo com Ancestrais do Continente Africano
Brasail
Ensaio de Imunoadsorção Enzimática
Feminino
Infecções por HIV/imunologia
Infecções por HIV/transmissão
HIV-1/imunologia
Análise Heteroduplex
Humanos
Masculino
Meia-Idade
Filogenia
Reação em Cadeia da Polimerase
Comportamento Sexual
Fatores Socioeconômicos
Abuso de Substâncias por Via Intravenosa/complicações
title_short HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics
title_full HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics
title_fullStr HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics
title_full_unstemmed HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics
title_sort HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics
author Fernandez, José Carlos Couto
author_facet Fernandez, José Carlos Couto
Morgado, Mariza Gonçalves
Bongertz, Vera
Tanuri, Amilcar
Andrade, Tarcisio Mattos de
Alves, Carlos Roberto Brites
Castro Filho, Bernardo Galvão
author_role author
author2 Morgado, Mariza Gonçalves
Bongertz, Vera
Tanuri, Amilcar
Andrade, Tarcisio Mattos de
Alves, Carlos Roberto Brites
Castro Filho, Bernardo Galvão
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Fernandez, José Carlos Couto
Morgado, Mariza Gonçalves
Bongertz, Vera
Tanuri, Amilcar
Andrade, Tarcisio Mattos de
Alves, Carlos Roberto Brites
Castro Filho, Bernardo Galvão
dc.subject.en.pt_BR.fl_str_mv HIV-1
Subtypes
Diversity
Brazil
topic HIV-1
Subtypes
Diversity
Brazil
Variação Antigênica
Infecções por HIV/virologia
HIV-1/classificação
Adolescente
Adulto
África/etnologia
Grupo com Ancestrais do Continente Africano
Brasail
Ensaio de Imunoadsorção Enzimática
Feminino
Infecções por HIV/imunologia
Infecções por HIV/transmissão
HIV-1/imunologia
Análise Heteroduplex
Humanos
Masculino
Meia-Idade
Filogenia
Reação em Cadeia da Polimerase
Comportamento Sexual
Fatores Socioeconômicos
Abuso de Substâncias por Via Intravenosa/complicações
dc.subject.decs.pt_BR.fl_str_mv Variação Antigênica
Infecções por HIV/virologia
HIV-1/classificação
Adolescente
Adulto
África/etnologia
Grupo com Ancestrais do Continente Africano
Brasail
Ensaio de Imunoadsorção Enzimática
Feminino
Infecções por HIV/imunologia
Infecções por HIV/transmissão
HIV-1/imunologia
Análise Heteroduplex
Humanos
Masculino
Meia-Idade
Filogenia
Reação em Cadeia da Polimerase
Comportamento Sexual
Fatores Socioeconômicos
Abuso de Substâncias por Via Intravenosa/complicações
description Fundação Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil
publishDate 1999
dc.date.issued.fl_str_mv 1999
dc.date.accessioned.fl_str_mv 2012-10-04T20:34:19Z
dc.date.available.fl_str_mv 2012-10-04T20:34:19Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv COUTO-FERNANDEZ, J.C. et al. HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics. Journal of Acquired Immune Deficience Syndromes v. 22, n. 3, p. 288-93, nov. 1999.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/5646
dc.identifier.issn.none.fl_str_mv 1525-4135
identifier_str_mv COUTO-FERNANDEZ, J.C. et al. HIV-1 subtyping in Salvador, Bahia, Brazil: a city with African sociodemographic characteristics. Journal of Acquired Immune Deficience Syndromes v. 22, n. 3, p. 288-93, nov. 1999.
1525-4135
url https://www.arca.fiocruz.br/handle/icict/5646
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/5646/1/Couto-Fernandes%20HIV_1_Subtyping_in_Salvador%2c_Bahia%2c_Brazil__A_City.11%5b1%5d.pdf
https://www.arca.fiocruz.br/bitstream/icict/5646/2/license.txt
https://www.arca.fiocruz.br/bitstream/icict/5646/5/Couto-Fernandes%20HIV_1_Subtyping_in_Salvador%2c_Bahia%2c_Brazil__A_City.11%5b1%5d.pdf.txt
https://www.arca.fiocruz.br/bitstream/icict/5646/4/Couto-Fernandes%20HIV_1_Subtyping_in_Salvador%2c_Bahia%2c_Brazil__A_City.11%5b1%5d.pdf.jpg
bitstream.checksum.fl_str_mv c4d52085f0cd1c6b1513fbae32f04c21
06db3f0df647fd9ddff657403bbe0ee2
6d93d3216dc4a7f5df47d4876fbec4d3
6f1ebd4c8aeeff13725a72d7ca57c9e3
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1798325016392105984

Registros relacionados