Effect of selection for eventing on the MSTN gene in Brazilian sport horses

Bibliographic Details
Main Author: Padilha, Felipe Gomes Ferreira
Publication Date: 2018
Other Authors: El-Jaick, Kênia Balbi, Castro, Liane de, Moreira, Aline dos Santos, Ferreira, Ana Maria Reis
Format: Article
Language: eng
Source: Repositório Institucional da FIOCRUZ (ARCA)
Download full: https://www.arca.fiocruz.br/handle/icict/33743
Summary: Universidade Federal Fluminense. Niterói, RJ, Brasil.
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spelling Padilha, Felipe Gomes FerreiraEl-Jaick, Kênia BalbiCastro, Liane deMoreira, Aline dos SantosFerreira, Ana Maria Reis2019-07-01T12:50:04Z2019-07-01T12:50:04Z2018PADILHA, Felipe Gomes Ferreira et al. Effect of selection for eventing on the MSTN gene in Brazilian sport horses. Journal of Equine Science, v. 29, n. 1, p. 21-24, 2018.1340-3516https://www.arca.fiocruz.br/handle/icict/3374310.1294/jes.29.211347-7501engJapanese Society of Equine ScienceEffect of selection for eventing on the MSTN gene in Brazilian sport horsesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal Fluminense. Niterói, RJ, Brasil.Universidade Federal do Estado do Rio de Janeiro. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil.Universidade Federal Fluminense. Niterói, RJ, Brasil.Polymorphisms in MSTN have previously been associated with equine performance. Therefore, the aim of this study was to identify variants in MSTN intron 1 in 16 Brazilian sport horses selected for competition in eventing and their possible effects of selection on performance. Among the nine variants identified, eight had already been reported in previous studies or genomic databases, although they showed differences in frequencies when compared with other horse breeds. Moreover, a new mutation was identified in two horses, both in heterozygous form. Considering the absence of molecular studies in this valuable Brazilian breed, these findings represent an important contribution to the characterization of its genetic profile and may possibly aid in further genotype-phenotype association studies.Brazilian horseMyostatinPerformanceSkeletal muscleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/33743/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Padilha_Felipe_etal_INI_2018.pdfve_Padilha_Felipe_etal_INI_2018.pdfapplication/pdf532776https://www.arca.fiocruz.br/bitstream/icict/33743/2/ve_Padilha_Felipe_etal_INI_2018.pdf7fd33917c5cbb39d153f865838ac9bc3MD52TEXTve_Padilha_Felipe_etal_INI_2018.pdf.txtve_Padilha_Felipe_etal_INI_2018.pdf.txtExtracted texttext/plain16786https://www.arca.fiocruz.br/bitstream/icict/33743/3/ve_Padilha_Felipe_etal_INI_2018.pdf.txt990211f8994a7b2ab3d04b8dfa947417MD53icict/337432019-07-02 02:03:05.151oai:www.arca.fiocruz.br:icict/33743Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-07-02T05:03:05Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Effect of selection for eventing on the MSTN gene in Brazilian sport horses
title Effect of selection for eventing on the MSTN gene in Brazilian sport horses
spellingShingle Effect of selection for eventing on the MSTN gene in Brazilian sport horses
Padilha, Felipe Gomes Ferreira
Brazilian horse
Myostatin
Performance
Skeletal muscle
title_short Effect of selection for eventing on the MSTN gene in Brazilian sport horses
title_full Effect of selection for eventing on the MSTN gene in Brazilian sport horses
title_fullStr Effect of selection for eventing on the MSTN gene in Brazilian sport horses
title_full_unstemmed Effect of selection for eventing on the MSTN gene in Brazilian sport horses
title_sort Effect of selection for eventing on the MSTN gene in Brazilian sport horses
author Padilha, Felipe Gomes Ferreira
author_facet Padilha, Felipe Gomes Ferreira
El-Jaick, Kênia Balbi
Castro, Liane de
Moreira, Aline dos Santos
Ferreira, Ana Maria Reis
author_role author
author2 El-Jaick, Kênia Balbi
Castro, Liane de
Moreira, Aline dos Santos
Ferreira, Ana Maria Reis
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Padilha, Felipe Gomes Ferreira
El-Jaick, Kênia Balbi
Castro, Liane de
Moreira, Aline dos Santos
Ferreira, Ana Maria Reis
dc.subject.en.pt_BR.fl_str_mv Brazilian horse
Myostatin
Performance
Skeletal muscle
topic Brazilian horse
Myostatin
Performance
Skeletal muscle
description Universidade Federal Fluminense. Niterói, RJ, Brasil.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-07-01T12:50:04Z
dc.date.available.fl_str_mv 2019-07-01T12:50:04Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv PADILHA, Felipe Gomes Ferreira et al. Effect of selection for eventing on the MSTN gene in Brazilian sport horses. Journal of Equine Science, v. 29, n. 1, p. 21-24, 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/33743
dc.identifier.issn.pt_BR.fl_str_mv 1340-3516
dc.identifier.doi.pt_BR.fl_str_mv 10.1294/jes.29.21
dc.identifier.eissn.none.fl_str_mv 1347-7501
identifier_str_mv PADILHA, Felipe Gomes Ferreira et al. Effect of selection for eventing on the MSTN gene in Brazilian sport horses. Journal of Equine Science, v. 29, n. 1, p. 21-24, 2018.
1340-3516
10.1294/jes.29.21
1347-7501
url https://www.arca.fiocruz.br/handle/icict/33743
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Japanese Society of Equine Science
publisher.none.fl_str_mv Japanese Society of Equine Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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