Prevalence of arbovirus antibodies in young healthy adult population in Brazil

Detalhes bibliográficos
Autor(a) principal: Salgado, Bárbara Batista
Data de Publicação: 2021
Outros Autores: Maués, Fábio Carmona de Jesus, Pereira, Renato Lemos, Chiang, Jannifer Oliveira, Freitas, Maria Nazaré de Oliveira, Ferreira, Milene Silveira, Martins, Lívia Caricio, Vasconcelos, Pedro Fernando da Costa, Ganoza, Christian, Lalwani, Pritesh
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/59929
Resumo: Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brazil.
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spelling Salgado, Bárbara BatistaMaués, Fábio Carmona de JesusPereira, Renato LemosChiang, Jannifer OliveiraFreitas, Maria Nazaré de OliveiraFerreira, Milene SilveiraMartins, Lívia CaricioVasconcelos, Pedro Fernando da CostaGanoza, ChristianLalwani, Pritesh2023-08-09T18:09:42Z2023-08-09T18:09:42Z2021SALGADO, Bárbara Batista et al. Prevalence of arbovirus antibodies in young healthy adult population in Brazil. Parasites & Vectors, v. 14, n. 1, p. 1-11, Aug. 2021.1756-3305https://www.arca.fiocruz.br/handle/icict/5992910.1186/s13071-021-04901-4engBioMed CentralPrevalence of arbovirus antibodies in young healthy adult population in Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brazil.Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brazil.Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brazil / Centro de Instrução de Guerra na Selva. Manaus, AM, Brazil.Instituto Evandro Chagas. Seção de Arbovirologia e Febres Hemorrágicas. Ananindeua, PA, Brazil.Instituto Evandro Chagas. Seção de Arbovirologia e Febres Hemorrágicas. Ananindeua, PA, Brazil.Instituto Evandro Chagas. Seção de Arbovirologia e Febres Hemorrágicas. Ananindeua, PA, Brazil.Instituto Evandro Chagas. Seção de Arbovirologia e Febres Hemorrágicas. Ananindeua, PA, Brazil.Instituto Evandro Chagas. Seção de Arbovirologia e Febres Hemorrágicas. Ananindeua, PA, Brazil.Universidad Peruana Cayetano Heredia. Instituto de Medicina Tropical Alexander von Humboldt. Lima, Perú.Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brazil.Background: The emergence and re-emergence of infectious diseases are a cause for worldwide concern. The introduction of Zika and Chikungunya diseases in the Americas has exposed unforeseen medical and logistical challenges for public health systems. Moreover, the lack of preventive measures and vaccination against known and emerging mosquito-transmitted pathogens, and the occurrence of unanticipated clinical complications, has had an enormous social and economic impact on the affected populations. In this study, we aimed to measure the seroprevalence of endemic and emerging viral pathogens in military personnel stationed in Manaus, Amazonas state. Methods: We measured the seropositivity of antibodies against 19 endemic and emerging viruses in a healthy military personnel group using a hemagglutination inhibition assay (HIA). Results: Overall, DENV positivity was 60.4%, and 30.9% of the individuals reacted against ZIKV. Also, 46.6%, 54.7%, 51.3% and 48.7% individuals reacted against West Nile virus (WNV), Saint Louis encephalitis virus (SLEV), Ilheus virus (ILHV) and Rocio virus (ROCV), respectively. Individuals with high DENV HIA titer reacted more frequently with ZIKV or WNV compared to those with low HIA titers. Observed cross-reactivity between Flaviviruses varied depending on the virus serogroup. Additionally, 0.6% and 0.3% individuals were seropositive for Oropouche virus (OROV) and Catu virus (CATUV) from the family Peribunyaviridae, respectively. All samples were negative for Eastern Equine Encephalitis virus (EEEV), Western Equine Encephalomyelitis virus (WEEV), Mayaro virus (MAYV), Mucambo virus (MUCV) and CHIKV from the family Togaviridae. Conclusions: A high proportion of individuals in our high-risk population (~ 60%) lacked antibodies against major endemic and emerging viruses, which makes them susceptible for further infections. Military personnel serving in the Amazon region could serve as sentinels to strengthen global infectious disease surveillance, particularly in remote areas.ArbovirusCross-reactivityHemagglutination inhibition assayMilitary personnelPublic healthSeroprevalenceinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/59929/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALve_Bárbara_Salgado_etal_ILMD_2021.pdfve_Bárbara_Salgado_etal_ILMD_2021.pdfapplication/pdf7093994https://www.arca.fiocruz.br/bitstream/icict/59929/2/ve_B%c3%a1rbara_Salgado_etal_ILMD_2021.pdf116c097813c4ae49f12bb16b70c70702MD52icict/599292023-11-13 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dc.title.en_US.fl_str_mv Prevalence of arbovirus antibodies in young healthy adult population in Brazil
title Prevalence of arbovirus antibodies in young healthy adult population in Brazil
spellingShingle Prevalence of arbovirus antibodies in young healthy adult population in Brazil
Salgado, Bárbara Batista
Arbovirus
Cross-reactivity
Hemagglutination inhibition assay
Military personnel
Public health
Seroprevalence
title_short Prevalence of arbovirus antibodies in young healthy adult population in Brazil
title_full Prevalence of arbovirus antibodies in young healthy adult population in Brazil
title_fullStr Prevalence of arbovirus antibodies in young healthy adult population in Brazil
title_full_unstemmed Prevalence of arbovirus antibodies in young healthy adult population in Brazil
title_sort Prevalence of arbovirus antibodies in young healthy adult population in Brazil
author Salgado, Bárbara Batista
author_facet Salgado, Bárbara Batista
Maués, Fábio Carmona de Jesus
Pereira, Renato Lemos
Chiang, Jannifer Oliveira
Freitas, Maria Nazaré de Oliveira
Ferreira, Milene Silveira
Martins, Lívia Caricio
Vasconcelos, Pedro Fernando da Costa
Ganoza, Christian
Lalwani, Pritesh
author_role author
author2 Maués, Fábio Carmona de Jesus
Pereira, Renato Lemos
Chiang, Jannifer Oliveira
Freitas, Maria Nazaré de Oliveira
Ferreira, Milene Silveira
Martins, Lívia Caricio
Vasconcelos, Pedro Fernando da Costa
Ganoza, Christian
Lalwani, Pritesh
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Salgado, Bárbara Batista
Maués, Fábio Carmona de Jesus
Pereira, Renato Lemos
Chiang, Jannifer Oliveira
Freitas, Maria Nazaré de Oliveira
Ferreira, Milene Silveira
Martins, Lívia Caricio
Vasconcelos, Pedro Fernando da Costa
Ganoza, Christian
Lalwani, Pritesh
dc.subject.en.en_US.fl_str_mv Arbovirus
Cross-reactivity
Hemagglutination inhibition assay
Military personnel
topic Arbovirus
Cross-reactivity
Hemagglutination inhibition assay
Military personnel
Public health
Seroprevalence
dc.subject.en.none.fl_str_mv Public health
Seroprevalence
description Fundação Oswaldo Cruz. Instituto Leônidas e Maria Deane. Manaus, AM, Brazil.
publishDate 2021
dc.date.issued.fl_str_mv 2021
dc.date.accessioned.fl_str_mv 2023-08-09T18:09:42Z
dc.date.available.fl_str_mv 2023-08-09T18:09:42Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SALGADO, Bárbara Batista et al. Prevalence of arbovirus antibodies in young healthy adult population in Brazil. Parasites & Vectors, v. 14, n. 1, p. 1-11, Aug. 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/59929
dc.identifier.issn.en_US.fl_str_mv 1756-3305
dc.identifier.doi.none.fl_str_mv 10.1186/s13071-021-04901-4
identifier_str_mv SALGADO, Bárbara Batista et al. Prevalence of arbovirus antibodies in young healthy adult population in Brazil. Parasites & Vectors, v. 14, n. 1, p. 1-11, Aug. 2021.
1756-3305
10.1186/s13071-021-04901-4
url https://www.arca.fiocruz.br/handle/icict/59929
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/59929/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/59929/2/ve_B%c3%a1rbara_Salgado_etal_ILMD_2021.pdf
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