Thymus atrophy and double-positive escape are common features in infectious diseases

Detalhes bibliográficos
Autor(a) principal: Meis, Juliana de
Data de Publicação: 2012
Outros Autores: Oliveira, Désio Aurélio Farias de, Panzenhagen, Pedro H. Nunes, Maran, Naiara, Villa-Verde, Déa Maria Serra, Morrot, Alexandre, Savino, Wilson
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/18501
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil.
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spelling Meis, Juliana deOliveira, Désio Aurélio Farias dePanzenhagen, Pedro H. NunesMaran, NaiaraVilla-Verde, Déa Maria SerraMorrot, AlexandreSavino, Wilson2017-04-18T16:48:52Z2017-04-18T16:48:52Z2012MEIS, Juliana de: et al. Thymus Atrophy and Double-Positive Escape Are Common Features in Infectious Diseases. Journal of Parasitology Research, Volume 2012, Article ID 574020, 9p, 2012.2090-0023https://www.arca.fiocruz.br/handle/icict/1850110.1155/2012/5740202090-0031engHindawi Publishing CorporationTimoTrypanosoma cruziInfecçãoAtrofia do TimoLinfócitos do timoThymusThymus AtrophyTrypanosoma cruzi infectionthymus lymphocytesThymus atrophy and double-positive escape are common features in infectious diseasesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil.Universidade Federal do Rio de Janeiro. Instituto de Microbiologia. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil / Universidade Federal do Rio de Janeiro. Instituto de Microbiologia. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil.The thymus is a primary lymphoid organ in which bone marrow-derived T-cell precursors undergo differentiation, leading to migration of positively selected thymocytes to the T-cell-dependent areas of secondary lymphoid organs. This organ can undergo atrophy, caused by several endogenous and exogenous factors such as ageing, hormone fluctuations, and infectious agents. This paper will focus on emerging data on the thymic atrophy caused by infectious agents. We present data on the dynamics of thymus lymphocytes during acute Trypanosoma cruzi infection, showing that the resulting thymus atrophy comprises the abnormal release of thymic-derived T cells and may have an impact on host immune response.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/18501/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALdeamaria_vilaverde_etal_IOC_2012.pdfdeamaria_vilaverde_etal_IOC_2012.pdfapplication/pdf6758240https://www.arca.fiocruz.br/bitstream/icict/18501/2/deamaria_vilaverde_etal_IOC_2012.pdfe5dd935d53b2dde4f600d37aec8455a7MD52TEXTdeamaria_vilaverde_etal_IOC_2012.pdf.txtdeamaria_vilaverde_etal_IOC_2012.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Thymus atrophy and double-positive escape are common features in infectious diseases
title Thymus atrophy and double-positive escape are common features in infectious diseases
spellingShingle Thymus atrophy and double-positive escape are common features in infectious diseases
Meis, Juliana de
Timo
Trypanosoma cruzi
Infecção
Atrofia do Timo
Linfócitos do timo
Thymus
Thymus Atrophy
Trypanosoma cruzi infection
thymus lymphocytes
title_short Thymus atrophy and double-positive escape are common features in infectious diseases
title_full Thymus atrophy and double-positive escape are common features in infectious diseases
title_fullStr Thymus atrophy and double-positive escape are common features in infectious diseases
title_full_unstemmed Thymus atrophy and double-positive escape are common features in infectious diseases
title_sort Thymus atrophy and double-positive escape are common features in infectious diseases
author Meis, Juliana de
author_facet Meis, Juliana de
Oliveira, Désio Aurélio Farias de
Panzenhagen, Pedro H. Nunes
Maran, Naiara
Villa-Verde, Déa Maria Serra
Morrot, Alexandre
Savino, Wilson
author_role author
author2 Oliveira, Désio Aurélio Farias de
Panzenhagen, Pedro H. Nunes
Maran, Naiara
Villa-Verde, Déa Maria Serra
Morrot, Alexandre
Savino, Wilson
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Meis, Juliana de
Oliveira, Désio Aurélio Farias de
Panzenhagen, Pedro H. Nunes
Maran, Naiara
Villa-Verde, Déa Maria Serra
Morrot, Alexandre
Savino, Wilson
dc.subject.other.pt_BR.fl_str_mv Timo
Trypanosoma cruzi
Infecção
Atrofia do Timo
Linfócitos do timo
topic Timo
Trypanosoma cruzi
Infecção
Atrofia do Timo
Linfócitos do timo
Thymus
Thymus Atrophy
Trypanosoma cruzi infection
thymus lymphocytes
dc.subject.en.pt_BR.fl_str_mv Thymus
Thymus Atrophy
Trypanosoma cruzi infection
thymus lymphocytes
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa sobre o Timo. Rio de Janeiro, RJ. Brasil.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2017-04-18T16:48:52Z
dc.date.available.fl_str_mv 2017-04-18T16:48:52Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MEIS, Juliana de: et al. Thymus Atrophy and Double-Positive Escape Are Common Features in Infectious Diseases. Journal of Parasitology Research, Volume 2012, Article ID 574020, 9p, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/18501
dc.identifier.issn.pt_BR.fl_str_mv 2090-0023
dc.identifier.doi.none.fl_str_mv 10.1155/2012/574020
dc.identifier.eissn.none.fl_str_mv 2090-0031
identifier_str_mv MEIS, Juliana de: et al. Thymus Atrophy and Double-Positive Escape Are Common Features in Infectious Diseases. Journal of Parasitology Research, Volume 2012, Article ID 574020, 9p, 2012.
2090-0023
10.1155/2012/574020
2090-0031
url https://www.arca.fiocruz.br/handle/icict/18501
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Hindawi Publishing Corporation
publisher.none.fl_str_mv Hindawi Publishing Corporation
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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https://www.arca.fiocruz.br/bitstream/icict/18501/3/deamaria_vilaverde_etal_IOC_2012.pdf.txt
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