Maternal and neonatal outcomes of sars-cov-2 infection in a cohort of pregnant women with comorbid disorders

Detalhes bibliográficos
Autor(a) principal: Teixeira, Maria de Lourdes Benamor
Data de Publicação: 2021
Outros Autores: Ferreira Júnior, Orlando da Costa, João, Esaú, Fuller, Trevon, Esteves, Juliana Silva, Mendes-Silva, Wallace, Mocarzel, Carolina Carvalho, Maia, Richard Araújo, Boullosa, Lídia Theodoro, Gonçalves, Cássia Cristina Alves, Frankel, Patrícia Pontes, Gouvêa, Maria Isabel Fragoso da Silveira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/48907
Resumo: Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Hospital Federal dos Servidores do Estado. Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.
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spelling Teixeira, Maria de Lourdes BenamorFerreira Júnior, Orlando da CostaJoão, EsaúFuller, TrevonEsteves, Juliana SilvaMendes-Silva, WallaceMocarzel, Carolina CarvalhoMaia, Richard AraújoBoullosa, Lídia TheodoroGonçalves, Cássia Cristina AlvesFrankel, Patrícia PontesGouvêa, Maria Isabel Fragoso da Silveira2021-09-01T22:48:08Z2021-09-01T22:48:08Z2021TEIXEIRA, Maria de Lourdes Benamor et al. Maternal and Neonatal Outcomes of SARS-CoV-2 Infection in a Cohort of Pregnant Women with Comorbid Disorders. Viruses, v. 13, n. 7, p. 1-10, 2021.1999-4915https://www.arca.fiocruz.br/handle/icict/4890710.3390/v13071277engMDPIMaternal and neonatal outcomes of sars-cov-2 infection in a cohort of pregnant women with comorbid disordersinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Hospital Federal dos Servidores do Estado. Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Biologia. Departamento de Genética. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil.Hospital Federal dos Servidores do Estado. Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Hospital Federal dos Servidores do Estado. Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.Hospital Federal dos Servidores do Estado. Departamento Materno-Fetal e Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.Hospital Federal dos Servidores do Estado. Departamento Materno-Fetal e Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro. Maternidade Escola. Programa de Saúde Perinatal. Rio de Janeiro, RJ, Brasil.Hospital Federal dos Servidores do Estado. Departamento Materno-Fetal e Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Biologia. Departamento de Genética. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Biologia. Departamento de Genética. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Instituto de Biologia. Departamento de Genética. Laboratório de Biologia Molecular. Rio de Janeiro, RJ, Brasil.Hospital Federal dos Servidores do Estado. Departamento Materno-Fetal e Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Hospital Federal dos Servidores do Estado. Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.There are some reports and case series addressing Coronavirus Disease 2019 (COVID-19) infections during pregnancy in upper income countries, but there are few data on pregnant women with comorbid conditions in low and middle income Countries. This study evaluated the proportion and the maternal and neonatal outcomes associated with SARS-CoV-2 infection among pregnant women with comorbidities. Participants were recruited consecutively in order of admission to a maternity for pregnant women with comorbidities. Sociodemographic, clinical, and laboratory data were prospectively collected during hospitalization. Pregnant women were screened at entry: nasopharyngeal swabs were tested by RT-PCR; serum samples were tested for IgG antibodies against spike protein by ELISA. From April to June 2020, 115 eligible women were included in the study. The proportion of SARS-CoV-2 infection was 28.7%. The rate of obesity was 60.9%, vascular hypertension 40.0%, and HIV 21.7%. The most common clinical presentations were ageusia (21.2%), anosmia (18.2%), and fever (18.2%). Prematurity was higher among mothers who had a SARS-CoV-2 infection based on RT-PCR. There were two cases of fetal demise. We found a high proportion of COVID-19 among pregnant women with comorbidities. This underscores the importance of antenatal care during the pandemic to implement universal SARS-CoV-2 screening, precautionary measures, and the rollout of vaccination programs for pregnant women.HIVSARS-CoV-2ObesityObstetricsPregnancyinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/48907/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALMaternal_Maria_Teixeira_etal_INI_2021_COVID-19.pdfMaternal_Maria_Teixeira_etal_INI_2021_COVID-19.pdfapplication/pdf438648https://www.arca.fiocruz.br/bitstream/icict/48907/2/Maternal_Maria_Teixeira_etal_INI_2021_COVID-19.pdfd7445df859eb4edfd6c771f1fde818b6MD52TEXTMaternal_Maria_Teixeira_etal_INI_2021_COVID-19.pdf.txtMaternal_Maria_Teixeira_etal_INI_2021_COVID-19.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Maternal and neonatal outcomes of sars-cov-2 infection in a cohort of pregnant women with comorbid disorders
title Maternal and neonatal outcomes of sars-cov-2 infection in a cohort of pregnant women with comorbid disorders
spellingShingle Maternal and neonatal outcomes of sars-cov-2 infection in a cohort of pregnant women with comorbid disorders
Teixeira, Maria de Lourdes Benamor
HIV
SARS-CoV-2
Obesity
Obstetrics
Pregnancy
title_short Maternal and neonatal outcomes of sars-cov-2 infection in a cohort of pregnant women with comorbid disorders
title_full Maternal and neonatal outcomes of sars-cov-2 infection in a cohort of pregnant women with comorbid disorders
title_fullStr Maternal and neonatal outcomes of sars-cov-2 infection in a cohort of pregnant women with comorbid disorders
title_full_unstemmed Maternal and neonatal outcomes of sars-cov-2 infection in a cohort of pregnant women with comorbid disorders
title_sort Maternal and neonatal outcomes of sars-cov-2 infection in a cohort of pregnant women with comorbid disorders
author Teixeira, Maria de Lourdes Benamor
author_facet Teixeira, Maria de Lourdes Benamor
Ferreira Júnior, Orlando da Costa
João, Esaú
Fuller, Trevon
Esteves, Juliana Silva
Mendes-Silva, Wallace
Mocarzel, Carolina Carvalho
Maia, Richard Araújo
Boullosa, Lídia Theodoro
Gonçalves, Cássia Cristina Alves
Frankel, Patrícia Pontes
Gouvêa, Maria Isabel Fragoso da Silveira
author_role author
author2 Ferreira Júnior, Orlando da Costa
João, Esaú
Fuller, Trevon
Esteves, Juliana Silva
Mendes-Silva, Wallace
Mocarzel, Carolina Carvalho
Maia, Richard Araújo
Boullosa, Lídia Theodoro
Gonçalves, Cássia Cristina Alves
Frankel, Patrícia Pontes
Gouvêa, Maria Isabel Fragoso da Silveira
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Teixeira, Maria de Lourdes Benamor
Ferreira Júnior, Orlando da Costa
João, Esaú
Fuller, Trevon
Esteves, Juliana Silva
Mendes-Silva, Wallace
Mocarzel, Carolina Carvalho
Maia, Richard Araújo
Boullosa, Lídia Theodoro
Gonçalves, Cássia Cristina Alves
Frankel, Patrícia Pontes
Gouvêa, Maria Isabel Fragoso da Silveira
dc.subject.en.pt_BR.fl_str_mv HIV
SARS-CoV-2
Obesity
Obstetrics
Pregnancy
topic HIV
SARS-CoV-2
Obesity
Obstetrics
Pregnancy
description Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Hospital Federal dos Servidores do Estado. Departamento de Doenças Infecciosas. Rio de Janeiro, RJ, Brasil.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-09-01T22:48:08Z
dc.date.available.fl_str_mv 2021-09-01T22:48:08Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv TEIXEIRA, Maria de Lourdes Benamor et al. Maternal and Neonatal Outcomes of SARS-CoV-2 Infection in a Cohort of Pregnant Women with Comorbid Disorders. Viruses, v. 13, n. 7, p. 1-10, 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/48907
dc.identifier.issn.pt_BR.fl_str_mv 1999-4915
dc.identifier.doi.none.fl_str_mv 10.3390/v13071277
identifier_str_mv TEIXEIRA, Maria de Lourdes Benamor et al. Maternal and Neonatal Outcomes of SARS-CoV-2 Infection in a Cohort of Pregnant Women with Comorbid Disorders. Viruses, v. 13, n. 7, p. 1-10, 2021.
1999-4915
10.3390/v13071277
url https://www.arca.fiocruz.br/handle/icict/48907
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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