Time to Harmonize Dengue Nomenclature and Classification

Detalhes bibliográficos
Autor(a) principal: Cuypers, Lize
Data de Publicação: 2018
Outros Autores: Libin, Pieter J. K., Simmonds, Peter, Nowé, Ann, Muñoz-Jordán, Jorge, Alcantara, Luiz Carlos Junior, Vandamme, Anne-Mieke, Santiago, Gilberto A., Theys, Kristof
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/31612
Resumo: Rega Institute for Medical Research, Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Leuven, Belgium / University of Oxford. Nuffield Department of Mediciine. Oxford, UK.
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spelling Cuypers, LizeLibin, Pieter J. K.Simmonds, PeterNowé, AnnMuñoz-Jordán, JorgeAlcantara, Luiz Carlos JuniorVandamme, Anne-MiekeSantiago, Gilberto A.Theys, Kristof2019-02-13T17:15:27Z2019-02-13T17:15:27Z2018CUYPERS, Lize; et al. Time to Harmonize Dengue Nomenclature and Classification. Viruses, v.10, n.569, 7p, 2018.1999-4915https://www.arca.fiocruz.br/handle/icict/3161210.3390/v10100569engMDPIVírus da DengueClassificaçãoNomenclaturaDiversidadeDengue virusClassificationNomenclatureDiversityTime to Harmonize Dengue Nomenclature and Classificationinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleRega Institute for Medical Research, Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Leuven, Belgium / University of Oxford. Nuffield Department of Mediciine. Oxford, UK.Rega Institute for Medical Research, Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Leuven, Belgium / Vrije Universiteit Brussel. Department of Computer Science. Artifical Intelligence Lab. Brussels, Belgium.University of Oxford. Nuffield Department of Mediciine. Oxford, UK.Vrije Universiteit Brussel. Department of Computer Science. Artifical Intelligence Lab. Brussels, Belgium.Centers for Disease Control and Prevention. Dengue Branch. Division of Vector-Borne Diseases. San Juan, Porto Rico.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Flavivírus. Rio de Janeiro, RJ, Brasil.Rega Institute for Medical Research, Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Leuven, Belgium / Universidade Nova de Lisboa. Instituto de Higiene e Medicina Tropical. Unidade de Microbiologia. Global Health and Tropical Medicine. Lisboa, Portugal.Centers for Disease Control and Prevention. Dengue Branch. Division of Vector-Borne Diseases. San Juan, Porto Rico.Rega Institute for Medical Research, Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Leuven, Belgium.Dengue virus (DENV) is estimated to cause 390 million infections per year worldwide. A quarter of these infections manifest clinically and are associated with a morbidity and mortality that put a significant burden on the affected regions. Reports of increased frequency, intensity, and extended geographical range of outbreaks highlight the virus's ongoing global spread. Persistent transmission in endemic areas and the emergence in territories formerly devoid of transmission have shaped DENV's current genetic diversity and divergence. This genetic layout is hierarchically organized in serotypes, genotypes, and sub-genotypic clades. While serotypes are well defined, the genotype nomenclature and classification system lack consistency, which complicates a broader analysis of their clinical and epidemiological characteristics. We identify five key challenges: (1) Currently, there is no formal definition of a DENV genotype; (2) Two different nomenclature systems are used in parallel, which causes significant confusion; (3) A standardized classification procedure is lacking so far; (4) No formal definition of sub-genotypic clades is in place; (5) There is no consensus on how to report antigenic diversity. Therefore, we believe that the time is right to re-evaluate DENV genetic diversity in an essential effort to provide harmonization across DENV studies.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/31612/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALluizcarlos_alcantara_etal_IOC_2018.pdfluizcarlos_alcantara_etal_IOC_2018.pdfapplication/pdf388320https://www.arca.fiocruz.br/bitstream/icict/31612/2/luizcarlos_alcantara_etal_IOC_2018.pdfb6c1fd92c855e358ef28a18fb0e01277MD52TEXTluizcarlos_alcantara_etal_IOC_2018.pdf.txtluizcarlos_alcantara_etal_IOC_2018.pdf.txtExtracted texttext/plain23656https://www.arca.fiocruz.br/bitstream/icict/31612/3/luizcarlos_alcantara_etal_IOC_2018.pdf.txt6dec88634166bdb6c33d88cc1eec4e95MD53icict/316122022-06-24 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dc.title.pt_BR.fl_str_mv Time to Harmonize Dengue Nomenclature and Classification
title Time to Harmonize Dengue Nomenclature and Classification
spellingShingle Time to Harmonize Dengue Nomenclature and Classification
Cuypers, Lize
Vírus da Dengue
Classificação
Nomenclatura
Diversidade
Dengue virus
Classification
Nomenclature
Diversity
title_short Time to Harmonize Dengue Nomenclature and Classification
title_full Time to Harmonize Dengue Nomenclature and Classification
title_fullStr Time to Harmonize Dengue Nomenclature and Classification
title_full_unstemmed Time to Harmonize Dengue Nomenclature and Classification
title_sort Time to Harmonize Dengue Nomenclature and Classification
author Cuypers, Lize
author_facet Cuypers, Lize
Libin, Pieter J. K.
Simmonds, Peter
Nowé, Ann
Muñoz-Jordán, Jorge
Alcantara, Luiz Carlos Junior
Vandamme, Anne-Mieke
Santiago, Gilberto A.
Theys, Kristof
author_role author
author2 Libin, Pieter J. K.
Simmonds, Peter
Nowé, Ann
Muñoz-Jordán, Jorge
Alcantara, Luiz Carlos Junior
Vandamme, Anne-Mieke
Santiago, Gilberto A.
Theys, Kristof
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Cuypers, Lize
Libin, Pieter J. K.
Simmonds, Peter
Nowé, Ann
Muñoz-Jordán, Jorge
Alcantara, Luiz Carlos Junior
Vandamme, Anne-Mieke
Santiago, Gilberto A.
Theys, Kristof
dc.subject.other.pt_BR.fl_str_mv Vírus da Dengue
Classificação
Nomenclatura
Diversidade
topic Vírus da Dengue
Classificação
Nomenclatura
Diversidade
Dengue virus
Classification
Nomenclature
Diversity
dc.subject.en.pt_BR.fl_str_mv Dengue virus
Classification
Nomenclature
Diversity
description Rega Institute for Medical Research, Clinical and Epidemiological Virology. Department of Microbiology and Immunology. Leuven, Belgium / University of Oxford. Nuffield Department of Mediciine. Oxford, UK.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-02-13T17:15:27Z
dc.date.available.fl_str_mv 2019-02-13T17:15:27Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv CUYPERS, Lize; et al. Time to Harmonize Dengue Nomenclature and Classification. Viruses, v.10, n.569, 7p, 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/31612
dc.identifier.issn.pt_BR.fl_str_mv 1999-4915
dc.identifier.doi.none.fl_str_mv 10.3390/v10100569
identifier_str_mv CUYPERS, Lize; et al. Time to Harmonize Dengue Nomenclature and Classification. Viruses, v.10, n.569, 7p, 2018.
1999-4915
10.3390/v10100569
url https://www.arca.fiocruz.br/handle/icict/31612
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/31612/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/31612/2/luizcarlos_alcantara_etal_IOC_2018.pdf
https://www.arca.fiocruz.br/bitstream/icict/31612/3/luizcarlos_alcantara_etal_IOC_2018.pdf.txt
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