Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil.

Detalhes bibliográficos
Autor(a) principal: Locateli, Dayse
Data de Publicação: 2007
Outros Autores: Stoco, Patrícia Hermes, Queiroz, Artur Trancoso Lopo de, Alcantara, Luiz Carlos Júnior, Ferreira, Luiz G. E, Zanetti, Carlos Roberto, Rodrigues, Rosângela, Grisard, Edmundo Carlos, Pinto, Aguinaldo R
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/9491
Resumo: UFSC. Laboratório de Imunologia Aplicada. Departamento de Microbiologia e Parasitologia. Florianópolis, SC, Brasil
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spelling Locateli, DayseStoco, Patrícia HermesQueiroz, Artur Trancoso Lopo deAlcantara, Luiz Carlos JúniorFerreira, Luiz G. EZanetti, Carlos RobertoRodrigues, RosângelaGrisard, Edmundo CarlosPinto, Aguinaldo R2015-02-11T16:35:14Z2015-02-11T16:35:14Z2007LOCATELI, D. et al. Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil. Journal of Medical Virology, v. 79, n. 10, p. 1455-1463, 20070146-6615https://www.arca.fiocruz.br/handle/icict/949110.1002/jmv.20955engWiley-Liss, INCMolecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil.info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUFSC. Laboratório de Imunologia Aplicada. Departamento de Microbiologia e Parasitologia. Florianópolis, SC, BrasilUFSC. Laboratórios de Protozoologia e de Bioinformática. Departamento de Microbiologia e Parasitologia. Florianópolis, SC, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. FBDC. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Laboratório Avançado de Saúde Pública. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde Pública. FBDC. Salvador, BA, BrasilHospital Regional Homero de Miranda Gomes. São José, SC, BrasilUFSC. Laboratório de Imunologia Aplicada. Departamento de Microbiologia e Parasitologia. Florianópolis, SC, BrasilInstituto Adolfo Lutz. Laboratório de Retrovírus. São Paulo, SP, BrasilUFSC. Laboratórios de Protozoologia e de Bioinformática. Departamento de Microbiologia e Parasitologia. Florianópolis, SC, BrasilUFSC. Laboratório de Imunologia Aplicada. Departamento de Microbiologia e Parasitologia. Florianópolis, SC, BrasilRecent studies have demonstrated an increased prevalence of human immunodeficiency virus type 1 (HIV-1) subtype C in southern Brazil. Although Santa Catarina State (SC) is located in this area and presents one of the country's highest incidences of HIV/AIDS, knowledge on the molecular epidemiology of HIV-1 in such State is lacking. The aim of this study was to investigate the HIV-1 molecular diversity and epidemiological profile of HIV-1-infected patients from SC. DNA samples were PCR amplified and HIV-1 subtypes were determined using both env and gag genes by direct sequencing. Phylogenetic analyses revealed that 48% were subtype C and 23% were subtype B. Possible recombinant forms were observed for both B/C (23%) and B/F (6%) subtypes. Our results, for the first time, identifies HIV-1 subtype C as a major clade circulating in SC and contributes to the understanding of HIV epidemics in the country by confirming the epidemic spread of the HIV-1 subtype C in southern Brazil.AIDSHIVSubtypesBrazilInfecções por HIV/epidemiologiaHIV-1/genéticaEpidemiologia MolecularAdultoBrasil/epidemiologiaFemininoGenes env/genéticaVariação GenéticaHIV-1/classificaçãoMasculinoHumanosFilogeniaRecombinação Genéticainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-81914https://www.arca.fiocruz.br/bitstream/icict/9491/1/license.txt7d48279ffeed55da8dfe2f8e81f3b81fMD51ORIGINALLocateli D. Molecular....pdfLocateli D. Molecular....pdfapplication/pdf182648https://www.arca.fiocruz.br/bitstream/icict/9491/2/Locateli%20D.%20Molecular....pdf93e90c3cf5e279ef1db4c007c1ef8cbbMD52TEXTLocateli D. 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dc.title.pt_BR.fl_str_mv Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil.
title Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil.
spellingShingle Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil.
Locateli, Dayse
AIDS
HIV
Subtypes
Brazil
Infecções por HIV/epidemiologia
HIV-1/genética
Epidemiologia Molecular
Adulto
Brasil/epidemiologia
Feminino
Genes env/genética
Variação Genética
HIV-1/classificação
Masculino
Humanos
Filogenia
Recombinação Genética
title_short Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil.
title_full Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil.
title_fullStr Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil.
title_full_unstemmed Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil.
title_sort Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil.
author Locateli, Dayse
author_facet Locateli, Dayse
Stoco, Patrícia Hermes
Queiroz, Artur Trancoso Lopo de
Alcantara, Luiz Carlos Júnior
Ferreira, Luiz G. E
Zanetti, Carlos Roberto
Rodrigues, Rosângela
Grisard, Edmundo Carlos
Pinto, Aguinaldo R
author_role author
author2 Stoco, Patrícia Hermes
Queiroz, Artur Trancoso Lopo de
Alcantara, Luiz Carlos Júnior
Ferreira, Luiz G. E
Zanetti, Carlos Roberto
Rodrigues, Rosângela
Grisard, Edmundo Carlos
Pinto, Aguinaldo R
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Locateli, Dayse
Stoco, Patrícia Hermes
Queiroz, Artur Trancoso Lopo de
Alcantara, Luiz Carlos Júnior
Ferreira, Luiz G. E
Zanetti, Carlos Roberto
Rodrigues, Rosângela
Grisard, Edmundo Carlos
Pinto, Aguinaldo R
dc.subject.en.pt_BR.fl_str_mv AIDS
HIV
Subtypes
Brazil
topic AIDS
HIV
Subtypes
Brazil
Infecções por HIV/epidemiologia
HIV-1/genética
Epidemiologia Molecular
Adulto
Brasil/epidemiologia
Feminino
Genes env/genética
Variação Genética
HIV-1/classificação
Masculino
Humanos
Filogenia
Recombinação Genética
dc.subject.decs.pt_BR.fl_str_mv Infecções por HIV/epidemiologia
HIV-1/genética
Epidemiologia Molecular
Adulto
Brasil/epidemiologia
Feminino
Genes env/genética
Variação Genética
HIV-1/classificação
Masculino
Humanos
Filogenia
Recombinação Genética
description UFSC. Laboratório de Imunologia Aplicada. Departamento de Microbiologia e Parasitologia. Florianópolis, SC, Brasil
publishDate 2007
dc.date.issued.fl_str_mv 2007
dc.date.accessioned.fl_str_mv 2015-02-11T16:35:14Z
dc.date.available.fl_str_mv 2015-02-11T16:35:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv LOCATELI, D. et al. Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil. Journal of Medical Virology, v. 79, n. 10, p. 1455-1463, 2007
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/9491
dc.identifier.issn.none.fl_str_mv 0146-6615
dc.identifier.doi.none.fl_str_mv 10.1002/jmv.20955
identifier_str_mv LOCATELI, D. et al. Molecular epidemiology of HIV-1 in Santa Catarina State confirms increases of subtype C in Southern Brazil. Journal of Medical Virology, v. 79, n. 10, p. 1455-1463, 2007
0146-6615
10.1002/jmv.20955
url https://www.arca.fiocruz.br/handle/icict/9491
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Wiley-Liss, INC
publisher.none.fl_str_mv Wiley-Liss, INC
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