Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/11115 |
Resumo: | Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil / Bahia State Center for Diabetes and Endocrinology. Salvador, BA, Brasil |
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Fernandes, Ligia GabrielliAlmeida, Maria da Conceição Chagas deAquino, Estela Maria Motta Lima Leão de2015-07-07T18:55:01Z2015-07-07T18:55:01Z2015FERNANDES, Ligia Gabrielli; ALMEIDA, Maria da Conceição Chagas de; AQUINO, Estela Maria Motta Lima Leão de. Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Maturitas, v. 81, n. 3, p. 398-405, 2015.1873-4111https://www.arca.fiocruz.br/handle/icict/1111510.1016/j.maturitas.2015.04.013engElsevierProposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil / Bahia State Center for Diabetes and Endocrinology. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil / Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, BrasilObjectives: To propose plausible criteria with which to identify menopausal women with PCOS. Study design: A cross-sectional study involving the baseline data of 713 menopausal women at admission to the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) in Salvador, Bahia, Brazil. Main outcome measures: PCOS was identified by the presence oftwo ofthree criteria.(1)Ahistory of amenorrhea or oligomenorrhea (OL) (regular intermenstrual intervals ≥35 days during reproductive life); (2) clinical or biochemical hyperandrogenism (HA), identified by a score ≥5 points in a hirsutism questionnaire constructed and validated for women in this age group, or total or free testosterone ≥the 95th percentile for women considered normal; (3) insulin resistance (IR) (a homeostatic model assessment [HOMA] index ≥ 2.2). Validation was performed using probable epidemiological endpoints. Results: According to these criteria, 7.6% of the women in the sample had PCOS. Of these, 7.4% had HA and OL, 72.2%hadHAand IR, 14.8%had OL and IRand 5.6%,hadHA, OL and IR.Women withPCOS were younger, had had fewer pregnancies and entered menopause earlier. Positive associations were found between PCOS and overweight (PR: 1.31; 95%CI: 1.18–1.46), obesity (1.44; 1.01–2.06), carbohydrate metabolism disorders (impaired glucose tolerance and diabetes mellitus) (1.30; 1.03–1.65), and with diabetes alone (1.41; 0.83–2.39), although this latter association failed to reach statistical significance. Conclusion: The women selected in accordance with these criteria had the characteristics of PCOS that are not only expected, but also widely associated with this disorder.Polycistic ovary syndromeMenopauseInsulin resistanceinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82354https://www.arca.fiocruz.br/bitstream/icict/11115/1/license.txt8b4c200b4e10021c5683c6ccaba07169MD51ORIGINALGabrielli L Proposed....pdfGabrielli L Proposed....pdfapplication/pdf776715https://www.arca.fiocruz.br/bitstream/icict/11115/2/Gabrielli%20L%20Proposed....pdf58513d557d0a7113262eaaa4b978d18cMD52TEXTGabrielli L Proposed....pdf.txtGabrielli L Proposed....pdf.txtExtracted texttext/plain43054https://www.arca.fiocruz.br/bitstream/icict/11115/3/Gabrielli%20L%20Proposed....pdf.txtf8e011904cab1025ba70a5fdac1958eaMD53icict/111152023-03-15 14:33:07.33oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-03-15T17:33:07Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.en.fl_str_mv |
Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). |
title |
Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). |
spellingShingle |
Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Fernandes, Ligia Gabrielli Polycistic ovary syndrome Menopause Insulin resistance |
title_short |
Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). |
title_full |
Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). |
title_fullStr |
Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). |
title_full_unstemmed |
Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). |
title_sort |
Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). |
author |
Fernandes, Ligia Gabrielli |
author_facet |
Fernandes, Ligia Gabrielli Almeida, Maria da Conceição Chagas de Aquino, Estela Maria Motta Lima Leão de |
author_role |
author |
author2 |
Almeida, Maria da Conceição Chagas de Aquino, Estela Maria Motta Lima Leão de |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Fernandes, Ligia Gabrielli Almeida, Maria da Conceição Chagas de Aquino, Estela Maria Motta Lima Leão de |
dc.subject.en.en.fl_str_mv |
Polycistic ovary syndrome Menopause Insulin resistance |
topic |
Polycistic ovary syndrome Menopause Insulin resistance |
description |
Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil / Bahia State Center for Diabetes and Endocrinology. Salvador, BA, Brasil |
publishDate |
2015 |
dc.date.accessioned.fl_str_mv |
2015-07-07T18:55:01Z |
dc.date.available.fl_str_mv |
2015-07-07T18:55:01Z |
dc.date.issued.fl_str_mv |
2015 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
FERNANDES, Ligia Gabrielli; ALMEIDA, Maria da Conceição Chagas de; AQUINO, Estela Maria Motta Lima Leão de. Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Maturitas, v. 81, n. 3, p. 398-405, 2015. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/11115 |
dc.identifier.issn.none.fl_str_mv |
1873-4111 |
dc.identifier.doi.none.fl_str_mv |
10.1016/j.maturitas.2015.04.013 |
identifier_str_mv |
FERNANDES, Ligia Gabrielli; ALMEIDA, Maria da Conceição Chagas de; AQUINO, Estela Maria Motta Lima Leão de. Proposed criteria for the identification of polycystic ovary syndrome following menopause: an ancillary study of the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Maturitas, v. 81, n. 3, p. 398-405, 2015. 1873-4111 10.1016/j.maturitas.2015.04.013 |
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https://www.arca.fiocruz.br/handle/icict/11115 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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Elsevier |
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Elsevier |
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