Glomeruloid hemangioma as a late manifestation of POEMS syndrome

Detalhes bibliográficos
Autor(a) principal: Amorim, G. Moreira
Data de Publicação: 2018
Outros Autores: Sodré, C., Falcão, E. Mastrangelo Marinho, Cuzzi, T., Fernandes, R. Timbó, Ramos-e-Silva, M.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/34227
Resumo: Tullia Cuzzi. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
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spelling Amorim, G. MoreiraSodré, C.Falcão, E. Mastrangelo MarinhoCuzzi, T.Fernandes, R. TimbóRamos-e-Silva, M.2019-07-18T13:30:48Z2019-07-18T13:30:48Z2018AMORIM, Gustavo Moreira et al. Glomeruloid hemangioma as a late manifestation of POEMS syndrome. Acta Dermatovenerologica Croatica, v. 26, n. 4, p. 321-324, 2018.1330-027Xhttps://www.arca.fiocruz.br/handle/icict/3422710.1111/j.1365-2230.2008.02997.x1847-6538Tullia Cuzzi. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil.Federal University of Rio de Janeiro. School of Medicine. Rio de Janeiro, RJ, Brazil / Federal University of Rio de Janeiro. University Hospital. Rio de Janeiro, RJ, Brazil.Glomeruloid hemangiomas were first described by Chan in 1990 as a cutaneous marker of POEMS syndrome (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal proteinemia, and Skin changes). POEMS syndrome is a multisystem disease with a significant cutaneous involvement. Among its manifestations, hemangiomas are common, observed in up to one third of the patients, and, although specific, the glomeruloid subtype is very rare. The vascular endothelium growth factor (VEGF) is an angiogenic stimulation factor, which also induces increased systemic vascular permeability. Thus, a scenario of overexpression of VEGF can credibly lead to the assumption of an association between cutaneous hemangiomas and systemic manifestations, implying prognostic and therapeutic considerations and reinforcing the importance of dermatological periodical consultations for these patients. We report the case of a patient in whom glomeruloid hemangiomas marked the recurrence of POEMS syndrome, occurring before the systemic symptoms.engCroatian Medical AssociationGlomeruloid hemangioma as a late manifestation of POEMS syndromeinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlePOEMS syndromeGlomeruloid hemangiomaVascular endothelium growth factorVEGFinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/34227/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Amorim_Gustavo_etal_INI_2018.pdfve_Amorim_Gustavo_etal_INI_2018.pdfapplication/pdf172997https://www.arca.fiocruz.br/bitstream/icict/34227/2/ve_Amorim_Gustavo_etal_INI_2018.pdfef9011883a75ae5522a29bb5c7a6360eMD52TEXTve_Amorim_Gustavo_etal_INI_2018.pdf.txtve_Amorim_Gustavo_etal_INI_2018.pdf.txtExtracted texttext/plain12087https://www.arca.fiocruz.br/bitstream/icict/34227/3/ve_Amorim_Gustavo_etal_INI_2018.pdf.txtbe0b11b8837a4a02a3bdc5b171ca07f7MD53icict/342272019-07-19 02:07:23.296oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-07-19T05:07:23Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Glomeruloid hemangioma as a late manifestation of POEMS syndrome
title Glomeruloid hemangioma as a late manifestation of POEMS syndrome
spellingShingle Glomeruloid hemangioma as a late manifestation of POEMS syndrome
Amorim, G. Moreira
POEMS syndrome
Glomeruloid hemangioma
Vascular endothelium growth factor
VEGF
title_short Glomeruloid hemangioma as a late manifestation of POEMS syndrome
title_full Glomeruloid hemangioma as a late manifestation of POEMS syndrome
title_fullStr Glomeruloid hemangioma as a late manifestation of POEMS syndrome
title_full_unstemmed Glomeruloid hemangioma as a late manifestation of POEMS syndrome
title_sort Glomeruloid hemangioma as a late manifestation of POEMS syndrome
author Amorim, G. Moreira
author_facet Amorim, G. Moreira
Sodré, C.
Falcão, E. Mastrangelo Marinho
Cuzzi, T.
Fernandes, R. Timbó
Ramos-e-Silva, M.
author_role author
author2 Sodré, C.
Falcão, E. Mastrangelo Marinho
Cuzzi, T.
Fernandes, R. Timbó
Ramos-e-Silva, M.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Amorim, G. Moreira
Sodré, C.
Falcão, E. Mastrangelo Marinho
Cuzzi, T.
Fernandes, R. Timbó
Ramos-e-Silva, M.
dc.subject.en.pt_BR.fl_str_mv POEMS syndrome
Glomeruloid hemangioma
Vascular endothelium growth factor
VEGF
topic POEMS syndrome
Glomeruloid hemangioma
Vascular endothelium growth factor
VEGF
description Tullia Cuzzi. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-07-18T13:30:48Z
dc.date.available.fl_str_mv 2019-07-18T13:30:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv AMORIM, Gustavo Moreira et al. Glomeruloid hemangioma as a late manifestation of POEMS syndrome. Acta Dermatovenerologica Croatica, v. 26, n. 4, p. 321-324, 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/34227
dc.identifier.issn.pt_BR.fl_str_mv 1330-027X
dc.identifier.doi.none.fl_str_mv 10.1111/j.1365-2230.2008.02997.x
dc.identifier.eissn.none.fl_str_mv 1847-6538
identifier_str_mv AMORIM, Gustavo Moreira et al. Glomeruloid hemangioma as a late manifestation of POEMS syndrome. Acta Dermatovenerologica Croatica, v. 26, n. 4, p. 321-324, 2018.
1330-027X
10.1111/j.1365-2230.2008.02997.x
1847-6538
url https://www.arca.fiocruz.br/handle/icict/34227
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Croatian Medical Association
publisher.none.fl_str_mv Croatian Medical Association
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
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