Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata

Detalhes bibliográficos
Autor(a) principal: Fernandes, Andréia da Silva
Data de Publicação: 2015
Outros Autores: Alencar, Alexandre Santos, Evangelista, Heitor, Mazzei, José Luiz, Felzenszwalb, Israel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/40352
Resumo: Universidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcântara Gomes. Departamento de Biofísica e Biometria. Rio de Janeiro, RJ, Brasil.
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spelling Fernandes, Andréia da SilvaAlencar, Alexandre SantosEvangelista, HeitorMazzei, José LuizFelzenszwalb, Israel2020-03-17T13:52:14Z2020-03-17T13:52:14Z2015FERNANDES, Andréia da Silva et al. Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata. Pharmacognosy Magazine, v. 11, n. 41, 2015.0973-1296https://www.arca.fiocruz.br/handle/icict/4035210.4103/0973-1296.149701engPhotoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinatainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcântara Gomes. Departamento de Biofísica e Biometria. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcântara Gomes. Departamento de Biofísica e Biometria. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcântara Gomes. Departamento de Biofísica e Biometria. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Plataforma de Análise Química. Rio de Janeiro, RJ, Brasil.Universidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcântara Gomes. Departamento de Biofísica e Biometria. Rio de Janeiro, RJ, Brasil.The Antarctic moss Sanionia uncinata (Hedw.) Loeske has shown high ultraviolet (UV)‑absorbers content after exposition to high levels of UV‑B radiation and can be an important source of antioxidants. Objective: The aim was to investigate photoprotection and mutagenicity by the aqueous extract (AE) and hydroethanolic extract (HE) from the Antarctic moss S. uncinata. Materials and Methods: Photoprotective activities were determined through survival curves of Escherichia coli strains, after UV irradiation in an aqueous solution of thymine and in vitro sun protection factor (SPF). The Salmonella/microsome assays were applied to assess the mutagenicity. Results: Both extracts induced photoprotection against UV‑C radiation. The AE showed a higher protection than the hydroethanolic one against UV‑induced thymine dimerization. The SPFs were low in both extracts. In association to benzophenone‑3 a significant increase in the SPF was detected for the AE, and a significant decrease was induced by the HE. No mutagenicity was found in the both extracts. Furthermore, it was observed absence of cytotoxicity. Conclusion: Water‑extractable compounds seem to contribute on photoprotection of this Antarctic moss.MossMutagenicityPhotoprotectionSun Protection FactorThymine‑Dimer Inhibitioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83094https://www.arca.fiocruz.br/bitstream/icict/40352/1/license.txt4567a98700b61d3191d4763a7ff1bb4dMD51ORIGINALPhcogMag_2015_11_41_38_149701.pdfPhcogMag_2015_11_41_38_149701.pdfapplication/pdf1345461https://www.arca.fiocruz.br/bitstream/icict/40352/2/PhcogMag_2015_11_41_38_149701.pdf3976bc8150eb4992a5390a0ef8013aaaMD52TEXTPhcogMag_2015_11_41_38_149701.pdf.txtPhcogMag_2015_11_41_38_149701.pdf.txtExtracted texttext/plain26210https://www.arca.fiocruz.br/bitstream/icict/40352/3/PhcogMag_2015_11_41_38_149701.pdf.txtd6b5619d577108c6d9bbec6575159095MD53icict/403522020-03-18 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dc.title.pt_BR.fl_str_mv Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata
title Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata
spellingShingle Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata
Fernandes, Andréia da Silva
Moss
Mutagenicity
Photoprotection
Sun Protection Factor
Thymine‑Dimer Inhibition
title_short Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata
title_full Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata
title_fullStr Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata
title_full_unstemmed Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata
title_sort Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata
author Fernandes, Andréia da Silva
author_facet Fernandes, Andréia da Silva
Alencar, Alexandre Santos
Evangelista, Heitor
Mazzei, José Luiz
Felzenszwalb, Israel
author_role author
author2 Alencar, Alexandre Santos
Evangelista, Heitor
Mazzei, José Luiz
Felzenszwalb, Israel
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Fernandes, Andréia da Silva
Alencar, Alexandre Santos
Evangelista, Heitor
Mazzei, José Luiz
Felzenszwalb, Israel
dc.subject.en.pt_BR.fl_str_mv Moss
Mutagenicity
Photoprotection
Sun Protection Factor
Thymine‑Dimer Inhibition
topic Moss
Mutagenicity
Photoprotection
Sun Protection Factor
Thymine‑Dimer Inhibition
description Universidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcântara Gomes. Departamento de Biofísica e Biometria. Rio de Janeiro, RJ, Brasil.
publishDate 2015
dc.date.issued.fl_str_mv 2015
dc.date.accessioned.fl_str_mv 2020-03-17T13:52:14Z
dc.date.available.fl_str_mv 2020-03-17T13:52:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv FERNANDES, Andréia da Silva et al. Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata. Pharmacognosy Magazine, v. 11, n. 41, 2015.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/40352
dc.identifier.issn.pt_BR.fl_str_mv 0973-1296
dc.identifier.eissn.none.fl_str_mv 10.4103/0973-1296.149701
identifier_str_mv FERNANDES, Andréia da Silva et al. Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata. Pharmacognosy Magazine, v. 11, n. 41, 2015.
0973-1296
10.4103/0973-1296.149701
url https://www.arca.fiocruz.br/handle/icict/40352
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
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bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/40352/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/40352/2/PhcogMag_2015_11_41_38_149701.pdf
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