Reactive oxygen species production and mitochondrial dysfunction contribute to quercetin induced death in Leishmania amazonensis

Detalhes bibliográficos
Autor(a) principal: Silva, Fernanda Fonseca
Data de Publicação: 2011
Outros Autores: Inacio, Job D. F., Canto-Cavalheiro, Marilene M., Amaral, Elmo Eduardo Almeida
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/30043
Resumo: Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica de Tripanosomatideos. Rio de Janeiro, RJ, Brasil.
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spelling Silva, Fernanda FonsecaInacio, Job D. F.Canto-Cavalheiro, Marilene M.Amaral, Elmo Eduardo Almeida2018-11-15T15:07:28Z2018-11-15T15:07:28Z2011SILVA, Fernanda Silva; et al. Reactive Oxygen Species Production and Mitochondrial Dysfunction Contribute to Quercetin Induced Death in Leishmania amazonensis. Plos One, v.6, n.2, e14666, 7p, Feb. 2011.1932-6203https://www.arca.fiocruz.br/handle/icict/3004310.1371/journal.pone.0014666engPublic Library of ScienceLeishmania amazonensisdisfunção mitocondrialquercetinaespécies de oxigênioProdução reativaMorteLeishmania amazonensisOxygen SpeciesReactive ProductionQuercetinMitochondrial DysfunctionDeathReactive oxygen species production and mitochondrial dysfunction contribute to quercetin induced death in Leishmania amazonensisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica de Tripanosomatideos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica de Tripanosomatideos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica de Tripanosomatideos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica de Tripanosomatideos. Rio de Janeiro, RJ, Brasil.Leishmaniasis, a parasitic disease caused by protozoa of the genus Leishmania, affects more than 12 million people worldwide. Quercetin has generated considerable interest as a pharmaceutical compound with a wide range of therapeutic activities. One such activity is exhibited against the bloodstream parasite Trypanosoma brucei and amastigotes of Leishmania donovani. However, the mechanism of protozoan action of quercetin has not been studied.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/30043/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALelmoeduardo_amaral_etal_IOC_2011.pdfelmoeduardo_amaral_etal_IOC_2011.pdfapplication/pdf382731https://www.arca.fiocruz.br/bitstream/icict/30043/2/elmoeduardo_amaral_etal_IOC_2011.pdfaab7cf7998ec393528598ddac2567138MD52TEXTelmoeduardo_amaral_etal_IOC_2011.pdf.txtelmoeduardo_amaral_etal_IOC_2011.pdf.txtExtracted texttext/plain33020https://www.arca.fiocruz.br/bitstream/icict/30043/3/elmoeduardo_amaral_etal_IOC_2011.pdf.txt5bbab83ae8d703e6250cf722f6a78fd7MD53icict/300432018-11-16 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dc.title.pt_BR.fl_str_mv Reactive oxygen species production and mitochondrial dysfunction contribute to quercetin induced death in Leishmania amazonensis
title Reactive oxygen species production and mitochondrial dysfunction contribute to quercetin induced death in Leishmania amazonensis
spellingShingle Reactive oxygen species production and mitochondrial dysfunction contribute to quercetin induced death in Leishmania amazonensis
Silva, Fernanda Fonseca
Leishmania amazonensis
disfunção mitocondrial
quercetina
espécies de oxigênio
Produção reativa
Morte
Leishmania amazonensis
Oxygen Species
Reactive Production
Quercetin
Mitochondrial Dysfunction
Death
title_short Reactive oxygen species production and mitochondrial dysfunction contribute to quercetin induced death in Leishmania amazonensis
title_full Reactive oxygen species production and mitochondrial dysfunction contribute to quercetin induced death in Leishmania amazonensis
title_fullStr Reactive oxygen species production and mitochondrial dysfunction contribute to quercetin induced death in Leishmania amazonensis
title_full_unstemmed Reactive oxygen species production and mitochondrial dysfunction contribute to quercetin induced death in Leishmania amazonensis
title_sort Reactive oxygen species production and mitochondrial dysfunction contribute to quercetin induced death in Leishmania amazonensis
author Silva, Fernanda Fonseca
author_facet Silva, Fernanda Fonseca
Inacio, Job D. F.
Canto-Cavalheiro, Marilene M.
Amaral, Elmo Eduardo Almeida
author_role author
author2 Inacio, Job D. F.
Canto-Cavalheiro, Marilene M.
Amaral, Elmo Eduardo Almeida
author2_role author
author
author
dc.contributor.author.fl_str_mv Silva, Fernanda Fonseca
Inacio, Job D. F.
Canto-Cavalheiro, Marilene M.
Amaral, Elmo Eduardo Almeida
dc.subject.other.pt_BR.fl_str_mv Leishmania amazonensis
disfunção mitocondrial
quercetina
espécies de oxigênio
Produção reativa
Morte
topic Leishmania amazonensis
disfunção mitocondrial
quercetina
espécies de oxigênio
Produção reativa
Morte
Leishmania amazonensis
Oxygen Species
Reactive Production
Quercetin
Mitochondrial Dysfunction
Death
dc.subject.en.pt_BR.fl_str_mv Leishmania amazonensis
Oxygen Species
Reactive Production
Quercetin
Mitochondrial Dysfunction
Death
description Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Bioquímica de Tripanosomatideos. Rio de Janeiro, RJ, Brasil.
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2018-11-15T15:07:28Z
dc.date.available.fl_str_mv 2018-11-15T15:07:28Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, Fernanda Silva; et al. Reactive Oxygen Species Production and Mitochondrial Dysfunction Contribute to Quercetin Induced Death in Leishmania amazonensis. Plos One, v.6, n.2, e14666, 7p, Feb. 2011.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/30043
dc.identifier.issn.pt_BR.fl_str_mv 1932-6203
dc.identifier.doi.none.fl_str_mv 10.1371/journal.pone.0014666
identifier_str_mv SILVA, Fernanda Silva; et al. Reactive Oxygen Species Production and Mitochondrial Dysfunction Contribute to Quercetin Induced Death in Leishmania amazonensis. Plos One, v.6, n.2, e14666, 7p, Feb. 2011.
1932-6203
10.1371/journal.pone.0014666
url https://www.arca.fiocruz.br/handle/icict/30043
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Public Library of Science
publisher.none.fl_str_mv Public Library of Science
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/30043/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/30043/2/elmoeduardo_amaral_etal_IOC_2011.pdf
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