17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2019 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/39802 |
Resumo: | Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil. |
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Azevedo, Ana Carolina CampiPascoal, Vanessa Peruhype MagalhāesReis, Jordana Grazziela Coelho dosAntonelli, Lis RibeiroPereira, Christiane CostaSpeziali, ElaineReis, Laise RodriguesLemos, Jandira AparecidaRibeiro, José Geraldo LeiteCamacho, Luiz Antônio BastosMaia, Maria de Lourdes de SousaLima, Sheila Maria Barbosa deSimões, MarisolMartins, Reinaldo de MenezesHomma, AkiraMalaquias, Luiz Cosme CottaTauil, Pedro LuizVasconcelos, Pedro Fernando CostaRomano, Alessandro Pecego MartinsDomingues, Carla MagdaCarvalho, Andréa Teixeira deMartins Filho, Olindo AssisCollaborative Group for Studies of Yellow Fever Vaccine2020-02-07T17:03:34Z2020-02-07T17:03:34Z2019AZEVEDO, Ana Carolina Campi et al. 17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil. Emerging Infectious Disease, v. 25, n. 8, p. 1511-1521, Aug. 2019.1080-6059https://www.arca.fiocruz.br/handle/icict/3980210.3201/eid2508.181432engCenters for Disease Control and Prevention17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil / Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.Prefeitura de Belo Horizonte. Secretaria de Saúde. Belo Horizonte, MG, Brasil.Estado de Minas Gerais. Secretaria de Saúde. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos Bio-Manguinhos. Rio de Janeiro, RJ, Brasil.Universidade Federal de Alfenas. Alfenas, MG, Brasil.Universidade de Brasília. Brasília, DF, Brasil.Instituto Evandro Chagas, Ananindeua, PA, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Brasília, DF, Brasil.Ministério da Saúde. Secretaria de Vigilância em Saúde. Brasília, DF, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.We evaluated the duration of neutralizing antibodies and the status of 17DD vaccine–specific T- and B-cell memory following primary and revaccination regimens for yellow fever (YF) in Brazil. We observed progressive decline of plaque-reduction neutralization test (PRNT) seropositivity and of the levels of effector memory CD4+ and CD8+ T cells, as well as interferon-γ+CD8+ T cells, 10 years after primary vaccination. Revaccination restored PRNT seropositivity as well as the levels of effector memory CD4+, CD8+, and interferon-γ+CD8+ T cells. Moreover, secondary or multiple vaccinations guarantee long-term persistence of PRNT positivity and cell-mediated memory 10 years after booster vaccination. These findings support the relevance of booster doses to heighten the 17DD-YF–specific immune response to guarantee the long-term persistence of memory components. Secondary or multiple vaccinations improved the correlates of protection triggered by 17DD-YF primary vaccination, indicating that booster regimens are needed to achieve efficient immunity in areas with high risk for virus transmissionYellow feverRevaccinationDisease-Endemic Areasinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83082https://www.arca.fiocruz.br/bitstream/icict/39802/1/license.txt9193a7c197bc67acd023525e72a03240MD51ORIGINAL17DD Yellow Fever Revaccination and Heightened.pdf17DD Yellow Fever Revaccination and Heightened.pdfapplication/pdf8474097https://www.arca.fiocruz.br/bitstream/icict/39802/2/17DD%20Yellow%20Fever%20Revaccination%20and%20Heightened.pdf1f686febebdf9a0ee4fb6524d3bf4198MD52TEXT17DD Yellow Fever Revaccination and Heightened.pdf.txt17DD Yellow Fever Revaccination and Heightened.pdf.txtExtracted 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| dc.title.pt_BR.fl_str_mv |
17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil |
| title |
17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil |
| spellingShingle |
17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil Azevedo, Ana Carolina Campi Yellow fever Revaccination Disease-Endemic Areas |
| title_short |
17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil |
| title_full |
17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil |
| title_fullStr |
17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil |
| title_full_unstemmed |
17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil |
| title_sort |
17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil |
| author |
Azevedo, Ana Carolina Campi |
| author_facet |
Azevedo, Ana Carolina Campi Pascoal, Vanessa Peruhype Magalhāes Reis, Jordana Grazziela Coelho dos Antonelli, Lis Ribeiro Pereira, Christiane Costa Speziali, Elaine Reis, Laise Rodrigues Lemos, Jandira Aparecida Ribeiro, José Geraldo Leite Camacho, Luiz Antônio Bastos Maia, Maria de Lourdes de Sousa Lima, Sheila Maria Barbosa de Simões, Marisol Martins, Reinaldo de Menezes Homma, Akira Malaquias, Luiz Cosme Cotta Tauil, Pedro Luiz Vasconcelos, Pedro Fernando Costa Romano, Alessandro Pecego Martins Domingues, Carla Magda Carvalho, Andréa Teixeira de Martins Filho, Olindo Assis Collaborative Group for Studies of Yellow Fever Vaccine |
| author_role |
author |
| author2 |
Pascoal, Vanessa Peruhype Magalhāes Reis, Jordana Grazziela Coelho dos Antonelli, Lis Ribeiro Pereira, Christiane Costa Speziali, Elaine Reis, Laise Rodrigues Lemos, Jandira Aparecida Ribeiro, José Geraldo Leite Camacho, Luiz Antônio Bastos Maia, Maria de Lourdes de Sousa Lima, Sheila Maria Barbosa de Simões, Marisol Martins, Reinaldo de Menezes Homma, Akira Malaquias, Luiz Cosme Cotta Tauil, Pedro Luiz Vasconcelos, Pedro Fernando Costa Romano, Alessandro Pecego Martins Domingues, Carla Magda Carvalho, Andréa Teixeira de Martins Filho, Olindo Assis Collaborative Group for Studies of Yellow Fever Vaccine |
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author author author author author author author author author author author author author author author author author author author author author author |
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Azevedo, Ana Carolina Campi Pascoal, Vanessa Peruhype Magalhāes Reis, Jordana Grazziela Coelho dos Antonelli, Lis Ribeiro Pereira, Christiane Costa Speziali, Elaine Reis, Laise Rodrigues Lemos, Jandira Aparecida Ribeiro, José Geraldo Leite Camacho, Luiz Antônio Bastos Maia, Maria de Lourdes de Sousa Lima, Sheila Maria Barbosa de Simões, Marisol Martins, Reinaldo de Menezes Homma, Akira Malaquias, Luiz Cosme Cotta Tauil, Pedro Luiz Vasconcelos, Pedro Fernando Costa Romano, Alessandro Pecego Martins Domingues, Carla Magda Carvalho, Andréa Teixeira de Martins Filho, Olindo Assis Collaborative Group for Studies of Yellow Fever Vaccine |
| dc.subject.en.pt_BR.fl_str_mv |
Yellow fever Revaccination Disease-Endemic Areas |
| topic |
Yellow fever Revaccination Disease-Endemic Areas |
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Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil. |
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2019 |
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2019 |
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2020-02-07T17:03:34Z |
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2020-02-07T17:03:34Z |
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info:eu-repo/semantics/article |
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AZEVEDO, Ana Carolina Campi et al. 17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil. Emerging Infectious Disease, v. 25, n. 8, p. 1511-1521, Aug. 2019. |
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https://www.arca.fiocruz.br/handle/icict/39802 |
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1080-6059 |
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10.3201/eid2508.181432 |
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AZEVEDO, Ana Carolina Campi et al. 17DD Yellow Fever Revaccination and Heightened Long-Term Immunity in Populations of Disease-Endemic Areas, Brazil. Emerging Infectious Disease, v. 25, n. 8, p. 1511-1521, Aug. 2019. 1080-6059 10.3201/eid2508.181432 |
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Centers for Disease Control and Prevention |
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Centers for Disease Control and Prevention |
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