Replication of dengue viruses in mosquito cell cultures: a model from ultrastructural observations
Autor(a) principal: | |
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Data de Publicação: | 1992 |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/43492 |
Resumo: | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. |
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Barth, Ortrud Monika2020-09-20T21:09:35Z2020-09-20T21:09:35Z1992BARTH, Ortrud Monika. Replication of dengue viruses in mosquito cell cultures: a model from ultrastructural observations. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 87, n. 4, p. 565-574, Oct./Dec. 1992.0074-0276https://www.arca.fiocruz.br/handle/icict/4349210.1590/S0074-027619920004000171678-8060engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.FlaviviridaeDengue tipo 1Dengue tipo 2Replicação do vírusUltraestruturaFlaviviridaeDengue 1Dengue 2Virus replicationUltrastructureReplication of dengue viruses in mosquito cell cultures: a model from ultrastructural observationsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil.Mosquito cell cultures infected with human sera from dengue-1 and dengue-2 outbreaks, started in Rio de Janeiro by 1986 and 1990 respectively, were examined by electron microscopy at different times post the infection of cell cultures. More information was obtained about cell penetration of virus particles in the presence or not of antibodies, their pathway inside the cells, replication mode and exit. Infectiveness of the virus at those different stages can only be attributed to the particles appearing inside the trans-Golgi vesicles; most of all newly formed virus particles remain inside the RER-derived cell vesicles or inside lysosomes, even during cell lysis. Groups of larges particles, 65-75 nm in diameter at dengue-2 infections, persist during cell passage. The large amounts of smooth membrane structures, as vesicles or tabules inside the RER are attributed to a cell response to viral infection.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/43492/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALOrtrudM-Barth_IOC_1992.pdfOrtrudM-Barth_IOC_1992.pdfapplication/pdf1050004https://www.arca.fiocruz.br/bitstream/icict/43492/2/OrtrudM-Barth_IOC_1992.pdf667c910ebd4e8a37dea327f76a28bcf5MD52TEXTOrtrudM-Barth_IOC_1992.pdf.txtOrtrudM-Barth_IOC_1992.pdf.txtExtracted texttext/plain10https://www.arca.fiocruz.br/bitstream/icict/43492/3/OrtrudM-Barth_IOC_1992.pdf.txt2c6eb67c8897d916ae47524b1a844d3fMD53icict/434922020-09-21 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dc.title.pt_BR.fl_str_mv |
Replication of dengue viruses in mosquito cell cultures: a model from ultrastructural observations |
title |
Replication of dengue viruses in mosquito cell cultures: a model from ultrastructural observations |
spellingShingle |
Replication of dengue viruses in mosquito cell cultures: a model from ultrastructural observations Barth, Ortrud Monika Flaviviridae Dengue tipo 1 Dengue tipo 2 Replicação do vírus Ultraestrutura Flaviviridae Dengue 1 Dengue 2 Virus replication Ultrastructure |
title_short |
Replication of dengue viruses in mosquito cell cultures: a model from ultrastructural observations |
title_full |
Replication of dengue viruses in mosquito cell cultures: a model from ultrastructural observations |
title_fullStr |
Replication of dengue viruses in mosquito cell cultures: a model from ultrastructural observations |
title_full_unstemmed |
Replication of dengue viruses in mosquito cell cultures: a model from ultrastructural observations |
title_sort |
Replication of dengue viruses in mosquito cell cultures: a model from ultrastructural observations |
author |
Barth, Ortrud Monika |
author_facet |
Barth, Ortrud Monika |
author_role |
author |
dc.contributor.author.fl_str_mv |
Barth, Ortrud Monika |
dc.subject.other.pt_BR.fl_str_mv |
Flaviviridae Dengue tipo 1 Dengue tipo 2 Replicação do vírus Ultraestrutura |
topic |
Flaviviridae Dengue tipo 1 Dengue tipo 2 Replicação do vírus Ultraestrutura Flaviviridae Dengue 1 Dengue 2 Virus replication Ultrastructure |
dc.subject.en.pt_BR.fl_str_mv |
Flaviviridae Dengue 1 Dengue 2 Virus replication Ultrastructure |
description |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. |
publishDate |
1992 |
dc.date.issued.fl_str_mv |
1992 |
dc.date.accessioned.fl_str_mv |
2020-09-20T21:09:35Z |
dc.date.available.fl_str_mv |
2020-09-20T21:09:35Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
BARTH, Ortrud Monika. Replication of dengue viruses in mosquito cell cultures: a model from ultrastructural observations. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 87, n. 4, p. 565-574, Oct./Dec. 1992. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/43492 |
dc.identifier.issn.pt_BR.fl_str_mv |
0074-0276 |
dc.identifier.doi.none.fl_str_mv |
10.1590/S0074-02761992000400017 |
dc.identifier.eissn.none.fl_str_mv |
1678-8060 |
identifier_str_mv |
BARTH, Ortrud Monika. Replication of dengue viruses in mosquito cell cultures: a model from ultrastructural observations. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 87, n. 4, p. 565-574, Oct./Dec. 1992. 0074-0276 10.1590/S0074-02761992000400017 1678-8060 |
url |
https://www.arca.fiocruz.br/handle/icict/43492 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. |
publisher.none.fl_str_mv |
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
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Fundação Oswaldo Cruz (FIOCRUZ) |
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FIOCRUZ |
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FIOCRUZ |
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Repositório Institucional da FIOCRUZ (ARCA) |
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