Brazilian dengue virus type 1 replication in mosquito cell cultures

Detalhes bibliográficos
Autor(a) principal: Barth,Ortrud Monika
Data de Publicação: 1992
Outros Autores: Schatzmayr,Hermann G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000100001
Resumo: The development of dengue viruses type 1 obtained from accute human sera and inoculated into mosquito cell cultures, was observed by standard transmission electron microscopy and cytochemical staining. It follows the trans-type mechanism already estabilished of other dengue types. Directed passage of single virus particles across the cell membrane seems to be a pathway of entry and exit in dengue-1 infected cells. The nature of numerous electron translucent vesicles and tubules, produced simmultaneously during virus replication inside the rough endoplasmic reticulum, was analyzed by cytochemical tests. The largest amount of virus particles was produced inside cell syncytia.
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spelling Brazilian dengue virus type 1 replication in mosquito cell culturesFlaviviridaedengue-1virus-replicationultrastructureThe development of dengue viruses type 1 obtained from accute human sera and inoculated into mosquito cell cultures, was observed by standard transmission electron microscopy and cytochemical staining. It follows the trans-type mechanism already estabilished of other dengue types. Directed passage of single virus particles across the cell membrane seems to be a pathway of entry and exit in dengue-1 infected cells. The nature of numerous electron translucent vesicles and tubules, produced simmultaneously during virus replication inside the rough endoplasmic reticulum, was analyzed by cytochemical tests. The largest amount of virus particles was produced inside cell syncytia.Instituto Oswaldo Cruz, Ministério da Saúde1992-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000100001Memórias do Instituto Oswaldo Cruz v.87 n.1 1992reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02761992000100001info:eu-repo/semantics/openAccessBarth,Ortrud MonikaSchatzmayr,Hermann G.eng2020-04-25T17:46:42Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:04:28.187Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Brazilian dengue virus type 1 replication in mosquito cell cultures
title Brazilian dengue virus type 1 replication in mosquito cell cultures
spellingShingle Brazilian dengue virus type 1 replication in mosquito cell cultures
Barth,Ortrud Monika
Flaviviridae
dengue-1
virus-replication
ultrastructure
title_short Brazilian dengue virus type 1 replication in mosquito cell cultures
title_full Brazilian dengue virus type 1 replication in mosquito cell cultures
title_fullStr Brazilian dengue virus type 1 replication in mosquito cell cultures
title_full_unstemmed Brazilian dengue virus type 1 replication in mosquito cell cultures
title_sort Brazilian dengue virus type 1 replication in mosquito cell cultures
author Barth,Ortrud Monika
author_facet Barth,Ortrud Monika
Schatzmayr,Hermann G.
author_role author
author2 Schatzmayr,Hermann G.
author2_role author
dc.contributor.author.fl_str_mv Barth,Ortrud Monika
Schatzmayr,Hermann G.
dc.subject.por.fl_str_mv Flaviviridae
dengue-1
virus-replication
ultrastructure
topic Flaviviridae
dengue-1
virus-replication
ultrastructure
dc.description.none.fl_txt_mv The development of dengue viruses type 1 obtained from accute human sera and inoculated into mosquito cell cultures, was observed by standard transmission electron microscopy and cytochemical staining. It follows the trans-type mechanism already estabilished of other dengue types. Directed passage of single virus particles across the cell membrane seems to be a pathway of entry and exit in dengue-1 infected cells. The nature of numerous electron translucent vesicles and tubules, produced simmultaneously during virus replication inside the rough endoplasmic reticulum, was analyzed by cytochemical tests. The largest amount of virus particles was produced inside cell syncytia.
description The development of dengue viruses type 1 obtained from accute human sera and inoculated into mosquito cell cultures, was observed by standard transmission electron microscopy and cytochemical staining. It follows the trans-type mechanism already estabilished of other dengue types. Directed passage of single virus particles across the cell membrane seems to be a pathway of entry and exit in dengue-1 infected cells. The nature of numerous electron translucent vesicles and tubules, produced simmultaneously during virus replication inside the rough endoplasmic reticulum, was analyzed by cytochemical tests. The largest amount of virus particles was produced inside cell syncytia.
publishDate 1992
dc.date.none.fl_str_mv 1992-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000100001
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761992000100001
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02761992000100001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.87 n.1 1992
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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