Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil

Detalhes bibliográficos
Autor(a) principal: Milhim, Bruno H G A
Data de Publicação: 2022
Outros Autores: Rocha, Leonardo C da, Terzian, Ana C B, Mazaro, Carolina C P, Augusto, Marcos T, Luchs, Adriana, Zini, Nathalia, Sacchetto, Livia, Santos, Barbara F Dos, Garcia, Pedro H C, Rocha, Rodrigo S, Liso, Elisabete, Brienze, Vânia M S, Silva, Gislaine C D da, Vasilakis, Nikos, Estofolete, Cássia F, Nogueira, Maurício L
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/56770
Resumo: Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.
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spelling Milhim, Bruno H G ARocha, Leonardo C daTerzian, Ana C BMazaro, Carolina C PAugusto, Marcos TLuchs, AdrianaZini, NathaliaSacchetto, LiviaSantos, Barbara F DosGarcia, Pedro H CRocha, Rodrigo SLiso, ElisabeteBrienze, Vânia M SSilva, Gislaine C D daVasilakis, NikosEstofolete, Cássia FNogueira, Maurício L2023-01-30T18:00:13Z2023-01-30T18:00:13Z2022MILHIM, Bruno H G A et al. Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil. Viruses, v. 14, n. 7, 1488, 2022. doi: 10.3390/v140714881999-4915https://www.arca.fiocruz.br/handle/icict/56770engMDPIArboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFaculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil/Fundação Oswaldo Cruz. Instituto René Rachou. Laboratório de Imunologia Celular e Molecular. Belo Horizonte, MG, Brazil/Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Hospital de Base. São José do Rio Preto, SP, Brazil.Hospital de Base. São José do Rio Preto, SP, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Department of Pathology. University of Texas Medical Branch. University Blvd. Galveston, TX, USA./Department of Preventive Medicine and Population Health. University of Texas Medical Branch. University Blvd. Galveston, TX, USA/ Center for Vector-Borne and Zoonotic Diseases. University of Texas Medical Branch. University Blvd. Galveston, TX, USA/Center for Biodefense and Emerging Infectious Diseases. University of Texas Medical Branch. University Blvd. Galveston, TX, USA/Center for Tropical Diseases. University of Texas Medical Branch. University Blvd. Galveston, TX, USA./ Institute for Human Infection and Immunity. University of Texas Medical Branch. University Blvd. Galveston, TX, USA.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil/Department of Pathology. University of Texas Medical Branch. University Blvd. Galveston, TX, USA.Arbovirus infections are increasingly important causes of disease, whose spectrum of neurological manifestations are not fully known. This study sought to retrospectively assess the incidence of arboviruses in cerebrospinal fluid samples of patients with neurological symptoms to inform diagnosis of central and peripheral nervous system disorders. A total of 255 cerebrospinal fluid (CSF) samples collected from January 2016 to December 2017 were tested for dengue virus (DENV 1-4), Zika virus (ZIKV), and Chikungunya virus (CHIKV) in addition to other neurotropic arboviruses of interest, using genetic and serologic assays. Of the 255 CSF samples analyzed, 3.53% (09/255) were positive for arboviruses presenting mainly as meningitis, encephalitis, and cerebrovascular events, of which ZIKV was detected in 2.74% (7/255), DENV in 0.78% (2/255), in addition to an identified ILHV infection that was described previously. All the cases were detected in adults aged 18 to 74 years old. Our findings highlight the scientific and clinical importance of neurological syndromes associated with arboviruses and demonstrate the relevance of specific laboratory methods to achieve accurate diagnoses as well as highlight the true dimension of these diseases to ultimately improve public health planning and medical case management.arbovirusneurological disorderssurveillanceinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/56770/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALArboviral Infections in Neurological Disorders in Hospitalized.pdfArboviral Infections in Neurological Disorders in Hospitalized.pdfapplication/pdf318650https://www.arca.fiocruz.br/bitstream/icict/56770/2/Arboviral%20Infections%20in%20Neurological%20Disorders%20in%20Hospitalized.pdf18ae1d9d3cb9b93d90d7be5a68895fe2MD52icict/567702023-01-30 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dc.title.en_US.fl_str_mv Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil
title Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil
spellingShingle Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil
Milhim, Bruno H G A
arbovirus
neurological disorders
surveillance
title_short Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil
title_full Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil
title_fullStr Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil
title_full_unstemmed Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil
title_sort Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil
author Milhim, Bruno H G A
author_facet Milhim, Bruno H G A
Rocha, Leonardo C da
Terzian, Ana C B
Mazaro, Carolina C P
Augusto, Marcos T
Luchs, Adriana
Zini, Nathalia
Sacchetto, Livia
Santos, Barbara F Dos
Garcia, Pedro H C
Rocha, Rodrigo S
Liso, Elisabete
Brienze, Vânia M S
Silva, Gislaine C D da
Vasilakis, Nikos
Estofolete, Cássia F
Nogueira, Maurício L
author_role author
author2 Rocha, Leonardo C da
Terzian, Ana C B
Mazaro, Carolina C P
Augusto, Marcos T
Luchs, Adriana
Zini, Nathalia
Sacchetto, Livia
Santos, Barbara F Dos
Garcia, Pedro H C
Rocha, Rodrigo S
Liso, Elisabete
Brienze, Vânia M S
Silva, Gislaine C D da
Vasilakis, Nikos
Estofolete, Cássia F
Nogueira, Maurício L
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Milhim, Bruno H G A
Rocha, Leonardo C da
Terzian, Ana C B
Mazaro, Carolina C P
Augusto, Marcos T
Luchs, Adriana
Zini, Nathalia
Sacchetto, Livia
Santos, Barbara F Dos
Garcia, Pedro H C
Rocha, Rodrigo S
Liso, Elisabete
Brienze, Vânia M S
Silva, Gislaine C D da
Vasilakis, Nikos
Estofolete, Cássia F
Nogueira, Maurício L
dc.subject.en.en_US.fl_str_mv arbovirus
neurological disorders
surveillance
topic arbovirus
neurological disorders
surveillance
description Faculdade de Medicina de São José do Rio Preto. Laboratório de Pesquisas em Virologia. São José do Rio Preto, SP, Brazil.
publishDate 2022
dc.date.issued.fl_str_mv 2022
dc.date.accessioned.fl_str_mv 2023-01-30T18:00:13Z
dc.date.available.fl_str_mv 2023-01-30T18:00:13Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv MILHIM, Bruno H G A et al. Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil. Viruses, v. 14, n. 7, 1488, 2022. doi: 10.3390/v14071488
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/56770
dc.identifier.issn.en_US.fl_str_mv 1999-4915
identifier_str_mv MILHIM, Bruno H G A et al. Arboviral Infections in Neurological Disorders in Hospitalized Patients in São José do Rio Preto, São Paulo, Brazil. Viruses, v. 14, n. 7, 1488, 2022. doi: 10.3390/v14071488
1999-4915
url https://www.arca.fiocruz.br/handle/icict/56770
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/56770/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/56770/2/Arboviral%20Infections%20in%20Neurological%20Disorders%20in%20Hospitalized.pdf
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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