Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device

Detalhes bibliográficos
Autor(a) principal: Fumoto, Hideyuki
Data de Publicação: 2012
Outros Autores: Gillinov, A. Marc, Saraiva, Roberto M., Horai, Tetsuya, Anzai, Tomohiro, Takaseya, Tohru, Shiose, Akira, Arakawa, Yoko, Vince, D. Geoffrey, Dessoffy, Raymond, Fukamachi, Kiyotaka
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/36526
Resumo: Roberto M. Saraiva. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
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spelling Fumoto, HideyukiGillinov, A. MarcSaraiva, Roberto M.Horai, TetsuyaAnzai, TomohiroTakaseya, TohruShiose, AkiraArakawa, YokoVince, D. GeoffreyDessoffy, RaymondFukamachi, Kiyotaka2019-10-17T14:13:21Z2019-10-17T14:13:21Z2012FUMOTO, Hideyuki et al. Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, v. 7, n. 3, p.195-200, 2012.1556-9845https://www.arca.fiocruz.br/handle/icict/3652610.1097/imi.0b013e3182618feb1559-0879Roberto M. Saraiva. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.2020-10-17Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Cleveland Clinic. Miller Heart and Vascular Institute. Department of Thoracic and Cardiovascular Surgery. Cleveland, OH, USA.Cleveland Clinic. Miller Heart and Vascular Institute. Department of Cardiovascular Medicine. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Objective: Exclusion of the left atrial appendage is proposed to reduce the risk of stroke in patients with atrial fibrillation. The aim of this study was to evaluate the feasibility and efficacy of a fourthgeneration atrial exclusion device developed for minimally invasive applications. Methods: The novel atrial exclusion device consists of two polymer beams and two elastomeric bands that connect the two beams at either end. Fifteen mongrel dogs were implanted with the device at the base of the left atrial appendage through a median sternotomy and were evaluated at 30 (n = 7), 90 (n = 6), and 180 (n = 2) days after implantation by epicardial echocardiography, left atrial and coronary angiography, gross pathology, and histology. Results: Left atrial appendage exclusion was completed without hemodynamic instability. Coronary angiography revealed that the left circumflex artery was patent in all cases. A new endothelial tissue layer developed, as expected, on the occluded orifice of the left atrium. Conclusions: This novel atrial exclusion device achieved easy, reliable, and safe exclusion of the left atrial appendage, with favorable histological results in a canine model for up to 6 months. Clinical application could provide a new therapeutic option for reducing the risk of stroke in patients with atrial fibrillation.engLippincott, Williams & WilkinsLeft atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive deviceinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAtrial fibrillationFlutterAtriumMinimally invasive surgery,Strokeinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/36526/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Fumoto_Hideyuki_etal_INI_2012.pdfve_Fumoto_Hideyuki_etal_INI_2012.pdfapplication/pdf827183https://www.arca.fiocruz.br/bitstream/icict/36526/2/ve_Fumoto_Hideyuki_etal_INI_2012.pdf467c74c8f2a4d292f19bf5a171e506e3MD52TEXTve_Fumoto_Hideyuki_etal_INI_2012.pdf.txtve_Fumoto_Hideyuki_etal_INI_2012.pdf.txtExtracted texttext/plain28665https://www.arca.fiocruz.br/bitstream/icict/36526/3/ve_Fumoto_Hideyuki_etal_INI_2012.pdf.txt20b2710648dac1c1b8685112593a8b83MD53icict/365262021-03-24 16:32:37.666oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:37Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device
title Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device
spellingShingle Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device
Fumoto, Hideyuki
Atrial fibrillation
Flutter
Atrium
Minimally invasive surgery,
Stroke
title_short Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device
title_full Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device
title_fullStr Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device
title_full_unstemmed Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device
title_sort Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device
author Fumoto, Hideyuki
author_facet Fumoto, Hideyuki
Gillinov, A. Marc
Saraiva, Roberto M.
Horai, Tetsuya
Anzai, Tomohiro
Takaseya, Tohru
Shiose, Akira
Arakawa, Yoko
Vince, D. Geoffrey
Dessoffy, Raymond
Fukamachi, Kiyotaka
author_role author
author2 Gillinov, A. Marc
Saraiva, Roberto M.
Horai, Tetsuya
Anzai, Tomohiro
Takaseya, Tohru
Shiose, Akira
Arakawa, Yoko
Vince, D. Geoffrey
Dessoffy, Raymond
Fukamachi, Kiyotaka
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Fumoto, Hideyuki
Gillinov, A. Marc
Saraiva, Roberto M.
Horai, Tetsuya
Anzai, Tomohiro
Takaseya, Tohru
Shiose, Akira
Arakawa, Yoko
Vince, D. Geoffrey
Dessoffy, Raymond
Fukamachi, Kiyotaka
dc.subject.en.pt_BR.fl_str_mv Atrial fibrillation
Flutter
Atrium
Minimally invasive surgery,
Stroke
topic Atrial fibrillation
Flutter
Atrium
Minimally invasive surgery,
Stroke
description Roberto M. Saraiva. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
publishDate 2012
dc.date.issued.fl_str_mv 2012
dc.date.accessioned.fl_str_mv 2019-10-17T14:13:21Z
dc.date.available.fl_str_mv 2019-10-17T14:13:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv FUMOTO, Hideyuki et al. Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, v. 7, n. 3, p.195-200, 2012.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/36526
dc.identifier.issn.pt_BR.fl_str_mv 1556-9845
dc.identifier.doi.none.fl_str_mv 10.1097/imi.0b013e3182618feb
dc.identifier.eissn.none.fl_str_mv 1559-0879
identifier_str_mv FUMOTO, Hideyuki et al. Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, v. 7, n. 3, p.195-200, 2012.
1556-9845
10.1097/imi.0b013e3182618feb
1559-0879
url https://www.arca.fiocruz.br/handle/icict/36526
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Lippincott, Williams & Wilkins
publisher.none.fl_str_mv Lippincott, Williams & Wilkins
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/36526/1/license.txt
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