Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
Texto Completo: | https://www.arca.fiocruz.br/handle/icict/36526 |
Resumo: | Roberto M. Saraiva. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento. |
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Fumoto, HideyukiGillinov, A. MarcSaraiva, Roberto M.Horai, TetsuyaAnzai, TomohiroTakaseya, TohruShiose, AkiraArakawa, YokoVince, D. GeoffreyDessoffy, RaymondFukamachi, Kiyotaka2019-10-17T14:13:21Z2019-10-17T14:13:21Z2012FUMOTO, Hideyuki et al. Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, v. 7, n. 3, p.195-200, 2012.1556-9845https://www.arca.fiocruz.br/handle/icict/3652610.1097/imi.0b013e3182618feb1559-0879Roberto M. Saraiva. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.2020-10-17Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Cleveland Clinic. Miller Heart and Vascular Institute. Department of Thoracic and Cardiovascular Surgery. Cleveland, OH, USA.Cleveland Clinic. Miller Heart and Vascular Institute. Department of Cardiovascular Medicine. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Lerner Research Institute. Department of Biomedical Engineering. Cleveland, OH, USA.Objective: Exclusion of the left atrial appendage is proposed to reduce the risk of stroke in patients with atrial fibrillation. The aim of this study was to evaluate the feasibility and efficacy of a fourthgeneration atrial exclusion device developed for minimally invasive applications. Methods: The novel atrial exclusion device consists of two polymer beams and two elastomeric bands that connect the two beams at either end. Fifteen mongrel dogs were implanted with the device at the base of the left atrial appendage through a median sternotomy and were evaluated at 30 (n = 7), 90 (n = 6), and 180 (n = 2) days after implantation by epicardial echocardiography, left atrial and coronary angiography, gross pathology, and histology. Results: Left atrial appendage exclusion was completed without hemodynamic instability. Coronary angiography revealed that the left circumflex artery was patent in all cases. A new endothelial tissue layer developed, as expected, on the occluded orifice of the left atrium. Conclusions: This novel atrial exclusion device achieved easy, reliable, and safe exclusion of the left atrial appendage, with favorable histological results in a canine model for up to 6 months. Clinical application could provide a new therapeutic option for reducing the risk of stroke in patients with atrial fibrillation.engLippincott, Williams & WilkinsLeft atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive deviceinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleAtrial fibrillationFlutterAtriumMinimally invasive surgery,Strokeinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/36526/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALve_Fumoto_Hideyuki_etal_INI_2012.pdfve_Fumoto_Hideyuki_etal_INI_2012.pdfapplication/pdf827183https://www.arca.fiocruz.br/bitstream/icict/36526/2/ve_Fumoto_Hideyuki_etal_INI_2012.pdf467c74c8f2a4d292f19bf5a171e506e3MD52TEXTve_Fumoto_Hideyuki_etal_INI_2012.pdf.txtve_Fumoto_Hideyuki_etal_INI_2012.pdf.txtExtracted texttext/plain28665https://www.arca.fiocruz.br/bitstream/icict/36526/3/ve_Fumoto_Hideyuki_etal_INI_2012.pdf.txt20b2710648dac1c1b8685112593a8b83MD53icict/365262021-03-24 16:32:37.666oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352021-03-24T19:32:37Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
dc.title.pt_BR.fl_str_mv |
Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device |
title |
Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device |
spellingShingle |
Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device Fumoto, Hideyuki Atrial fibrillation Flutter Atrium Minimally invasive surgery, Stroke |
title_short |
Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device |
title_full |
Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device |
title_fullStr |
Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device |
title_full_unstemmed |
Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device |
title_sort |
Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device |
author |
Fumoto, Hideyuki |
author_facet |
Fumoto, Hideyuki Gillinov, A. Marc Saraiva, Roberto M. Horai, Tetsuya Anzai, Tomohiro Takaseya, Tohru Shiose, Akira Arakawa, Yoko Vince, D. Geoffrey Dessoffy, Raymond Fukamachi, Kiyotaka |
author_role |
author |
author2 |
Gillinov, A. Marc Saraiva, Roberto M. Horai, Tetsuya Anzai, Tomohiro Takaseya, Tohru Shiose, Akira Arakawa, Yoko Vince, D. Geoffrey Dessoffy, Raymond Fukamachi, Kiyotaka |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Fumoto, Hideyuki Gillinov, A. Marc Saraiva, Roberto M. Horai, Tetsuya Anzai, Tomohiro Takaseya, Tohru Shiose, Akira Arakawa, Yoko Vince, D. Geoffrey Dessoffy, Raymond Fukamachi, Kiyotaka |
dc.subject.en.pt_BR.fl_str_mv |
Atrial fibrillation Flutter Atrium Minimally invasive surgery, Stroke |
topic |
Atrial fibrillation Flutter Atrium Minimally invasive surgery, Stroke |
description |
Roberto M. Saraiva. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012 |
dc.date.accessioned.fl_str_mv |
2019-10-17T14:13:21Z |
dc.date.available.fl_str_mv |
2019-10-17T14:13:21Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
FUMOTO, Hideyuki et al. Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, v. 7, n. 3, p.195-200, 2012. |
dc.identifier.uri.fl_str_mv |
https://www.arca.fiocruz.br/handle/icict/36526 |
dc.identifier.issn.pt_BR.fl_str_mv |
1556-9845 |
dc.identifier.doi.none.fl_str_mv |
10.1097/imi.0b013e3182618feb |
dc.identifier.eissn.none.fl_str_mv |
1559-0879 |
identifier_str_mv |
FUMOTO, Hideyuki et al. Left atrial appendage occlusion: pilot study of a fourth-generation, minimally invasive device. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, v. 7, n. 3, p.195-200, 2012. 1556-9845 10.1097/imi.0b013e3182618feb 1559-0879 |
url |
https://www.arca.fiocruz.br/handle/icict/36526 |
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eng |
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eng |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.publisher.none.fl_str_mv |
Lippincott, Williams & Wilkins |
publisher.none.fl_str_mv |
Lippincott, Williams & Wilkins |
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reponame:Repositório Institucional da FIOCRUZ (ARCA) instname:Fundação Oswaldo Cruz (FIOCRUZ) instacron:FIOCRUZ |
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