Factors associated with hospital readmission in sickle cell disease

Detalhes bibliográficos
Autor(a) principal: Loureiro, Monique Morgado
Data de Publicação: 2009
Outros Autores: Rozenfeld, Suely, Carvalho, Marilia Sá, Portugal, Rodrigo Doyle
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
DOI: 10.1186/1471-2326-9-2
Texto Completo: https://www.arca.fiocruz.br/handle/icict/56040
Resumo: Rio de Janeiro Federal University. Rio de Janeiro, RJ, Brazil.
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spelling Loureiro, Monique MorgadoRozenfeld, SuelyCarvalho, Marilia SáPortugal, Rodrigo Doyle2022-12-18T19:54:53Z2022-12-18T19:54:53Z2009LOUREIRO, Monique Morgado et al. Factors associated with hospital readmission in sickle cell disease. BMC Blood Disorders, v 9, n. 2, p. 1-6, 27 Feb. 2009.1471-2326https://www.arca.fiocruz.br/handle/icict/5604010.1186/1471-2326-9-2engBioMed CentralFactors associated with hospital readmission in sickle cell diseaseinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleRio de Janeiro Federal University. Rio de Janeiro, RJ, Brazil.Oswaldo Cruz Foundation. National School of Public Health. Rio de Janeiro, RJ, Brazil.Oswaldo Cruz Foundation. National School of Public Health. Rio de Janeiro, RJ, Brazil.Rio de Janeiro Federal University. Rio de Janeiro, RJ, Brazil.Background: Sickle cell disease is the most frequent hereditary disease in Brazil, and people with the disease may be hospitalised several times in the course of their lives. The purpose of this study was to estimate the hazard ratios of factors associated with the time between hospital admissions. Methods: The study sample comprised all patients admitted, from 2000 to 2004, to a university hospital in Rio de Janeiro State, south-east Brazil, as a result of acute complications from sickle cell disease (SCD). Considering the statistical problem of studying individuals with multiple events over time, the following extensions of Cox's proportional hazard ratio model were compared: the independent increment marginal model (Andersen-Gill) and the random effects model. Results: The study considered 71 patients, who were admitted 223 times for acute events related to SCD. The hazard ratios for hospital readmission were statistically significant for the prior occurrence of vaso-occlusive crisis and development of renal failure. However, analysis of residuals of the marginal model revealed evidence of non-proportionality for some covariates. Conclusion: the results from applying the two models were generally similar, indicating that the findings are not highly sensitive to different approaches. The better fit by the frailty model suggests that there are unmeasured individual factors with impact on hospital readmission.Sickle Cell Diseaseinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/56040/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALFactorsAssociated.pdfapplication/pdf229653https://www.arca.fiocruz.br/bitstream/icict/56040/2/FactorsAssociated.pdfe4a3f1ba118430e33a473170dcad776eMD52icict/560402022-12-18 16:54:53.78oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-12-18T19:54:53Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv Factors associated with hospital readmission in sickle cell disease
title Factors associated with hospital readmission in sickle cell disease
spellingShingle Factors associated with hospital readmission in sickle cell disease
Loureiro, Monique Morgado
Sickle Cell Disease
title_short Factors associated with hospital readmission in sickle cell disease
title_full Factors associated with hospital readmission in sickle cell disease
title_fullStr Factors associated with hospital readmission in sickle cell disease
title_full_unstemmed Factors associated with hospital readmission in sickle cell disease
title_sort Factors associated with hospital readmission in sickle cell disease
author Loureiro, Monique Morgado
author_facet Loureiro, Monique Morgado
Rozenfeld, Suely
Carvalho, Marilia Sá
Portugal, Rodrigo Doyle
author_role author
author2 Rozenfeld, Suely
Carvalho, Marilia Sá
Portugal, Rodrigo Doyle
author2_role author
author
author
dc.contributor.author.fl_str_mv Loureiro, Monique Morgado
Rozenfeld, Suely
Carvalho, Marilia Sá
Portugal, Rodrigo Doyle
dc.subject.en.en_US.fl_str_mv Sickle Cell Disease
topic Sickle Cell Disease
description Rio de Janeiro Federal University. Rio de Janeiro, RJ, Brazil.
publishDate 2009
dc.date.issued.fl_str_mv 2009
dc.date.accessioned.fl_str_mv 2022-12-18T19:54:53Z
dc.date.available.fl_str_mv 2022-12-18T19:54:53Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv LOUREIRO, Monique Morgado et al. Factors associated with hospital readmission in sickle cell disease. BMC Blood Disorders, v 9, n. 2, p. 1-6, 27 Feb. 2009.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/56040
dc.identifier.issn.en_US.fl_str_mv 1471-2326
dc.identifier.doi.none.fl_str_mv 10.1186/1471-2326-9-2
identifier_str_mv LOUREIRO, Monique Morgado et al. Factors associated with hospital readmission in sickle cell disease. BMC Blood Disorders, v 9, n. 2, p. 1-6, 27 Feb. 2009.
1471-2326
10.1186/1471-2326-9-2
url https://www.arca.fiocruz.br/handle/icict/56040
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/56040/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/56040/2/FactorsAssociated.pdf
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