Epidemiology of sickle cell disease hospital admissions in Brazil

Detalhes bibliográficos
Autor(a) principal: Loureiro, Monique Morgado
Data de Publicação: 2005
Outros Autores: Rozenfeld, Suely
Tipo de documento: Artigo
Idioma: por
eng
Título da fonte: Revista de Saúde Pública
Texto Completo: https://www.revistas.usp.br/rsp/article/view/31963
Resumo: OBJECTIVE: Sickle cell disease is a hereditary disease, which affects mainly the black population. The aim of the present study was to analyze hospital admissions due to acute events resulting from sickle cell disease, at the epidemiological and clinical levels. METHODS: The study population included 9,349 patients with sickle cell disease admitted to hospitals in Bahia, Rio de Janeiro, and Sao Paulo, between 2000 and 2002. The national hospital database of the Brazilian Healthcare System was used. Response variables were death and mean duration of hospital admission. Covariables included sex, age, type of admission, and hospital legal status. Proportions were compared using Chi-square or Fischer tests; for continuous variables, the Mann-Whitney or Kruskall-Wallis tests were used. RESULTS: Median age ranged between 11.0 and 12.0 years, and 70% of admissions were of patients below age 20 years. Length of stay varied with age and type of admission. Emergency rooms were the most frequent form of admission (65.6 to 90.8%). Mortality was higher among adults. Median age of death was low (26.5 to 31.5 years). CONCLUSIONS: Our results confirm the high morbidity among youngsters and show a predominance of death among young adults.
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spelling Epidemiology of sickle cell disease hospital admissions in Brazil Epidemiologia de internações por doença falciforme no Brasil Anemia falciforme^i1^sepidemioloAnemia falciforme^i1^sdiagnóstSistemas de informação hospitalarSickle cell anemia^i2^sepidemiolSickle cell anemia^i2^sdiagnoHospital information system OBJECTIVE: Sickle cell disease is a hereditary disease, which affects mainly the black population. The aim of the present study was to analyze hospital admissions due to acute events resulting from sickle cell disease, at the epidemiological and clinical levels. METHODS: The study population included 9,349 patients with sickle cell disease admitted to hospitals in Bahia, Rio de Janeiro, and Sao Paulo, between 2000 and 2002. The national hospital database of the Brazilian Healthcare System was used. Response variables were death and mean duration of hospital admission. Covariables included sex, age, type of admission, and hospital legal status. Proportions were compared using Chi-square or Fischer tests; for continuous variables, the Mann-Whitney or Kruskall-Wallis tests were used. RESULTS: Median age ranged between 11.0 and 12.0 years, and 70% of admissions were of patients below age 20 years. Length of stay varied with age and type of admission. Emergency rooms were the most frequent form of admission (65.6 to 90.8%). Mortality was higher among adults. Median age of death was low (26.5 to 31.5 years). CONCLUSIONS: Our results confirm the high morbidity among youngsters and show a predominance of death among young adults. OBJETIVO: A doença falciforme é uma enfermidade hereditária que afeta principalmente a população negra. O estudo teve por objetivo analisar as internações devido às complicações da doença, com enfoque nos aspectos epidemiológicos e clínicos. MÉTODOS: A população estudada foi constituída de 9.349 pacientes com diagnóstico de doença falciforme internados em hospitais da Bahia, Rio de Janeiro e São Paulo, no período de 2000 a 2002. Utilizaram-se os dados do Sistema de Internações Hospitalares do Sistema Único de Saúde. As variáveis respostas foram o óbito e o tempo médio de permanência hospitalar. As covariáveis foram o sexo, a idade, o tipo de admissão e a natureza jurídica do hospital. As proporções foram comparadas utilizando-se o teste qui-quadrado ou de Fischer; e para as variáveis contínuas, foi utilizado o teste Mann-Whitney ou Kruskall-Wallis. RESULTADOS: A mediana de idade variou de 11,0 a 12,0 anos e cerca de 70% das internações foram abaixo dos 20 anos. A mediana de dias de permanência hospitalar variou com a idade e o tipo de admissão. O tipo de admissão mais freqüente foi pela emergência (65,6 a 90,8%). Foi observada maior letalidade hospitalar entre adultos. A mediana da idade do óbito foi baixa (26,5 a 31,5 anos). CONCLUSÕES: Os resultados confirmaram a alta morbidade na população jovem e evidenciaram predominância de óbitos entre adultos jovens. Universidade de São Paulo. Faculdade de Saúde Pública2005-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfapplication/pdfhttps://www.revistas.usp.br/rsp/article/view/3196310.1590/S0034-89102005000600012Revista de Saúde Pública; Vol. 39 No. 6 (2005); 943-949 Revista de Saúde Pública; Vol. 39 Núm. 6 (2005); 943-949 Revista de Saúde Pública; v. 39 n. 6 (2005); 943-949 1518-87870034-8910reponame:Revista de Saúde Públicainstname:Universidade de São Paulo (USP)instacron:USPporenghttps://www.revistas.usp.br/rsp/article/view/31963/33968https://www.revistas.usp.br/rsp/article/view/31963/33969Copyright (c) 2017 Revista de Saúde Públicainfo:eu-repo/semantics/openAccessLoureiro, Monique MorgadoRozenfeld, Suely2012-07-08T22:49:26Zoai:revistas.usp.br:article/31963Revistahttps://www.revistas.usp.br/rsp/indexONGhttps://www.revistas.usp.br/rsp/oairevsp@org.usp.br||revsp1@usp.br1518-87870034-8910opendoar:2012-07-08T22:49:26Revista de Saúde Pública - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Epidemiology of sickle cell disease hospital admissions in Brazil
Epidemiologia de internações por doença falciforme no Brasil
title Epidemiology of sickle cell disease hospital admissions in Brazil
spellingShingle Epidemiology of sickle cell disease hospital admissions in Brazil
Loureiro, Monique Morgado
Anemia falciforme^i1^sepidemiolo
Anemia falciforme^i1^sdiagnóst
Sistemas de informação hospitalar
Sickle cell anemia^i2^sepidemiol
Sickle cell anemia^i2^sdiagno
Hospital information system
title_short Epidemiology of sickle cell disease hospital admissions in Brazil
title_full Epidemiology of sickle cell disease hospital admissions in Brazil
title_fullStr Epidemiology of sickle cell disease hospital admissions in Brazil
title_full_unstemmed Epidemiology of sickle cell disease hospital admissions in Brazil
title_sort Epidemiology of sickle cell disease hospital admissions in Brazil
author Loureiro, Monique Morgado
author_facet Loureiro, Monique Morgado
Rozenfeld, Suely
author_role author
author2 Rozenfeld, Suely
author2_role author
dc.contributor.author.fl_str_mv Loureiro, Monique Morgado
Rozenfeld, Suely
dc.subject.por.fl_str_mv Anemia falciforme^i1^sepidemiolo
Anemia falciforme^i1^sdiagnóst
Sistemas de informação hospitalar
Sickle cell anemia^i2^sepidemiol
Sickle cell anemia^i2^sdiagno
Hospital information system
topic Anemia falciforme^i1^sepidemiolo
Anemia falciforme^i1^sdiagnóst
Sistemas de informação hospitalar
Sickle cell anemia^i2^sepidemiol
Sickle cell anemia^i2^sdiagno
Hospital information system
description OBJECTIVE: Sickle cell disease is a hereditary disease, which affects mainly the black population. The aim of the present study was to analyze hospital admissions due to acute events resulting from sickle cell disease, at the epidemiological and clinical levels. METHODS: The study population included 9,349 patients with sickle cell disease admitted to hospitals in Bahia, Rio de Janeiro, and Sao Paulo, between 2000 and 2002. The national hospital database of the Brazilian Healthcare System was used. Response variables were death and mean duration of hospital admission. Covariables included sex, age, type of admission, and hospital legal status. Proportions were compared using Chi-square or Fischer tests; for continuous variables, the Mann-Whitney or Kruskall-Wallis tests were used. RESULTS: Median age ranged between 11.0 and 12.0 years, and 70% of admissions were of patients below age 20 years. Length of stay varied with age and type of admission. Emergency rooms were the most frequent form of admission (65.6 to 90.8%). Mortality was higher among adults. Median age of death was low (26.5 to 31.5 years). CONCLUSIONS: Our results confirm the high morbidity among youngsters and show a predominance of death among young adults.
publishDate 2005
dc.date.none.fl_str_mv 2005-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/rsp/article/view/31963
10.1590/S0034-89102005000600012
url https://www.revistas.usp.br/rsp/article/view/31963
identifier_str_mv 10.1590/S0034-89102005000600012
dc.language.iso.fl_str_mv por
eng
language por
eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/rsp/article/view/31963/33968
https://www.revistas.usp.br/rsp/article/view/31963/33969
dc.rights.driver.fl_str_mv Copyright (c) 2017 Revista de Saúde Pública
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2017 Revista de Saúde Pública
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Saúde Pública
dc.source.none.fl_str_mv Revista de Saúde Pública; Vol. 39 No. 6 (2005); 943-949
Revista de Saúde Pública; Vol. 39 Núm. 6 (2005); 943-949
Revista de Saúde Pública; v. 39 n. 6 (2005); 943-949
1518-8787
0034-8910
reponame:Revista de Saúde Pública
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
institution USP
reponame_str Revista de Saúde Pública
collection Revista de Saúde Pública
repository.name.fl_str_mv Revista de Saúde Pública - Universidade de São Paulo (USP)
repository.mail.fl_str_mv revsp@org.usp.br||revsp1@usp.br
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