Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes

Detalhes bibliográficos
Autor(a) principal: Vasconcelos, Luydson Richardson Silva
Data de Publicação: 2011
Outros Autores: Fonseca, Juliana Pereira Lopes, Carmo, Rodrigo Feliciano do, Mendonça, Taciana Furtado de, Pereira, Valeria Rêgo Alves, Lucena-Silva, Norma, Pereira, Leila Maria Moreira Beltrão, Moura, Patrícia, Cavalcanti, Maria do Socorro de Mendonça
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/30797
Resumo: FACEPE (Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco) and Programa de Pós-Graduação em Bolsas da Universidade de Pernambuco.
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spelling Vasconcelos, Luydson Richardson SilvaFonseca, Juliana Pereira LopesCarmo, Rodrigo Feliciano doMendonça, Taciana Furtado dePereira, Valeria Rêgo AlvesLucena-Silva, NormaPereira, Leila Maria Moreira BeltrãoMoura, PatríciaCavalcanti, Maria do Socorro de Mendonça2018-12-28T13:12:26Z2018-12-28T13:12:26Z2011VASCONCELOS, Luydson Richardson Silva et al. Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes. International Journal of Infectious Diseases, v. 15, n. 8, p. e551–e557, 1 ago. 2011.1878-3511https://www.arca.fiocruz.br/handle/icict/3079710.1016/j.ijid.2011.04.008FACEPE (Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco) and Programa de Pós-Graduação em Bolsas da Universidade de Pernambuco.Universidade de Pernambuco. Instituto de Ciências Biológicas. Faculdade de Ciências Medicas. Recife PE, Brasil. / Instituto do Fígado de Pernambuco. Recife PE, Brasil.Universidade de Pernambuco. Instituto de Ciências Biológicas. Faculdade de Ciências Medicas. Recife PE, Brasil.Universidade de Pernambuco. Instituto de Ciências Biológicas. Faculdade de Ciências Medicas. Recife PE, Brasil.Universidade de Pernambuco. Instituto de Ciências Biológicas. Faculdade de Ciências Medicas. Recife PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil. / Instituto de Medicina Integral Professor Fernando Figueira. Recife PE, Brasil.Universidade de Pernambuco. Instituto de Ciências Biológicas. Faculdade de Ciências Medicas. Recife PE, Brasil. / Instituto do Fígado de Pernambuco. Recife PE, Brasil.Universidade de Pernambuco. Instituto de Ciências Biológicas. Faculdade de Ciências Medicas. Recife PE, Brasil.Universidade de Pernambuco. Instituto de Ciências Biológicas. Faculdade de Ciências Medicas. Recife PE, Brasil.Mannose-binding lectin (MBL) activates the complement system promoting opsonophagocytosis, which could represent an advantage for Mycobacterium leprae, an intracellular pathogen. Therefore, a single nucleotide polymorphism (SNP) in the MBL2 gene associated with low levels of MBL could confer protection against the development of leprosy disease.engMannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypesinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleMannose-binding lectinMBL2LeprosyInnate immunityAgePolymorphismAdolescenteAdultoIdade FatoresEnvelhecidoIdoso, 80 anos ou maisBrasilEstudos de caso-controleCriançaCriança, pré-escolarFêmeaGenótipoHaplótiposHumanosImunidade InataLepra / sangueLepra / microbiologiaMasculinoLectina de Ligação com Manose / sangueLectina de Ligação a Manose / genéticaMeia idadeMycobacterium leprae / genéticaOdds RatioPolimorfismo de nucleotídeo único / genéticaAdulto joveminfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; 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dc.title.pt_BR.fl_str_mv Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes
title Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes
spellingShingle Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes
Vasconcelos, Luydson Richardson Silva
Mannose-binding lectin
MBL2
Leprosy
Innate immunity
Age
Polymorphism
Adolescente
Adulto
Idade Fatores
Envelhecido
Idoso, 80 anos ou mais
Brasil
Estudos de caso-controle
Criança
Criança, pré-escolar
Fêmea
Genótipo
Haplótipos
Humanos
Imunidade Inata
Lepra / sangue
Lepra / microbiologia
Masculino
Lectina de Ligação com Manose / sangue
Lectina de Ligação a Manose / genética
Meia idade
Mycobacterium leprae / genética
Odds Ratio
Polimorfismo de nucleotídeo único / genética
Adulto jovem
title_short Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes
title_full Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes
title_fullStr Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes
title_full_unstemmed Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes
title_sort Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes
author Vasconcelos, Luydson Richardson Silva
author_facet Vasconcelos, Luydson Richardson Silva
Fonseca, Juliana Pereira Lopes
Carmo, Rodrigo Feliciano do
Mendonça, Taciana Furtado de
Pereira, Valeria Rêgo Alves
Lucena-Silva, Norma
Pereira, Leila Maria Moreira Beltrão
Moura, Patrícia
Cavalcanti, Maria do Socorro de Mendonça
author_role author
author2 Fonseca, Juliana Pereira Lopes
Carmo, Rodrigo Feliciano do
Mendonça, Taciana Furtado de
Pereira, Valeria Rêgo Alves
Lucena-Silva, Norma
Pereira, Leila Maria Moreira Beltrão
Moura, Patrícia
Cavalcanti, Maria do Socorro de Mendonça
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Vasconcelos, Luydson Richardson Silva
Fonseca, Juliana Pereira Lopes
Carmo, Rodrigo Feliciano do
Mendonça, Taciana Furtado de
Pereira, Valeria Rêgo Alves
Lucena-Silva, Norma
Pereira, Leila Maria Moreira Beltrão
Moura, Patrícia
Cavalcanti, Maria do Socorro de Mendonça
dc.subject.en.pt_BR.fl_str_mv Mannose-binding lectin
MBL2
Leprosy
Innate immunity
Age
Polymorphism
topic Mannose-binding lectin
MBL2
Leprosy
Innate immunity
Age
Polymorphism
Adolescente
Adulto
Idade Fatores
Envelhecido
Idoso, 80 anos ou mais
Brasil
Estudos de caso-controle
Criança
Criança, pré-escolar
Fêmea
Genótipo
Haplótipos
Humanos
Imunidade Inata
Lepra / sangue
Lepra / microbiologia
Masculino
Lectina de Ligação com Manose / sangue
Lectina de Ligação a Manose / genética
Meia idade
Mycobacterium leprae / genética
Odds Ratio
Polimorfismo de nucleotídeo único / genética
Adulto jovem
dc.subject.decs.pt_BR.fl_str_mv Adolescente
Adulto
Idade Fatores
Envelhecido
Idoso, 80 anos ou mais
Brasil
Estudos de caso-controle
Criança
Criança, pré-escolar
Fêmea
Genótipo
Haplótipos
Humanos
Imunidade Inata
Lepra / sangue
Lepra / microbiologia
Masculino
Lectina de Ligação com Manose / sangue
Lectina de Ligação a Manose / genética
Meia idade
Mycobacterium leprae / genética
Odds Ratio
Polimorfismo de nucleotídeo único / genética
Adulto jovem
description FACEPE (Fundação de Amparo à Ciência e Tecnologia do Estado de Pernambuco) and Programa de Pós-Graduação em Bolsas da Universidade de Pernambuco.
publishDate 2011
dc.date.issued.fl_str_mv 2011
dc.date.accessioned.fl_str_mv 2018-12-28T13:12:26Z
dc.date.available.fl_str_mv 2018-12-28T13:12:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv VASCONCELOS, Luydson Richardson Silva et al. Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes. International Journal of Infectious Diseases, v. 15, n. 8, p. e551–e557, 1 ago. 2011.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/30797
dc.identifier.issn.pt_BR.fl_str_mv 1878-3511
dc.identifier.doi.none.fl_str_mv 10.1016/j.ijid.2011.04.008
identifier_str_mv VASCONCELOS, Luydson Richardson Silva et al. Mannose-binding lectin serum levels in patients with leprosy are influenced by age and MBL2 genotypes. International Journal of Infectious Diseases, v. 15, n. 8, p. e551–e557, 1 ago. 2011.
1878-3511
10.1016/j.ijid.2011.04.008
url https://www.arca.fiocruz.br/handle/icict/30797
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
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instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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