An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS)

Detalhes bibliográficos
Autor(a) principal: Dalmazio, Ilza
Data de Publicação: 2008
Outros Autores: Alves, Tânia Maria Almeida, Augusti, Rodinei
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/53643
Resumo: CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO
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spelling Dalmazio, IlzaAlves, Tânia Maria AlmeidaAugusti, Rodinei2022-07-05T18:55:14Z2022-07-05T18:55:14Z2008DALMÁZIO, Ilza; ALVES, Tânia Maria Almeida; AUGUSTI, Rodinei. An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS). J. Braz. Chem. Soc., v. 19, n.1, p. 81-88, 2008. doi.org/10.1590/S0103-50532008000100013103-5053https://www.arca.fiocruz.br/handle/icict/5364310.1590/S0103-50532008000100013CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICOUniversidade Federal de Minas Gerais. Departamento de Química. Belo Horizonte, MG, BrazilFundação Oswaldo Cruz. Centro de Pesquisas Rene Rachou. Belo Horizonte, MG, BrazilUniversidade Federal de Minas Gerais. Departamento de Química. Belo Horizonte, MG, BrazilThe advanced oxidation of paracetamol (1) promoted by TiO2/UV system in aqueous medium was investigated. Continuous monitoring by several techniques, such as UV-Vis spectroscopy, HPLC (high performance liquid chromatography), TOC (total organic carbon), and ESI-MS (electrospray ionization mass spectrometry), revealed that whereas the removal of paracetamol was highly efficient under these conditions, its mineralization was not likewise accomplished. GC-MS (gas chromatography-mass spectrometry) analysis showed that hydroquinone, aliphatic carboxylic acids, monohydroxy and dihydroxy paracetamol were the main products formed as a result of such degradation process. Based on these results, a reaction route for the degradation of paracetamol induced by the TiO2/UV system was suggested. Fragmentation pathways, as obtained from the mass spectra data, were also proposed for the trimethylsilyl (TMS) derivatives of monohydroxy and dihydroxy paracetamolengSociedade Brasileira de QuímicaAn appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleparacetamoladvanced oxidation processGC-MSinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/53643/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALAn appraisal on the degradation of paracetamol.pdfAn appraisal on the degradation of paracetamol.pdfapplication/pdf409429https://www.arca.fiocruz.br/bitstream/icict/53643/2/An%20appraisal%20on%20the%20degradation%20of%20paracetamol.pdf768252f247d50290afac41e4b72e5f3eMD52icict/536432022-07-05 15:55:15.013oai:www.arca.fiocruz.br:icict/53643Tk9URTogUExBQ0UgWU9VUiBPV04gTElDRU5TRSBIRVJFClRoaXMgc2FtcGxlIGxpY2Vuc2UgaXMgcHJvdmlkZWQgZm9yIGluZm9ybWF0aW9uYWwgcHVycG9zZXMgb25seS4KCk5PTi1FWENMVVNJVkUgRElTVFJJQlVUSU9OIExJQ0VOU0UKCkJ5IHNpZ25pbmcgYW5kIHN1Ym1pdHRpbmcgdGhpcyBsaWNlbnNlLCB5b3UgKHRoZSBhdXRob3Iocykgb3IgY29weXJpZ2h0Cm93bmVyKSBncmFudHMgdG8gRFNwYWNlIFVuaXZlcnNpdHkgKERTVSkgdGhlIG5vbi1leGNsdXNpdmUgcmlnaHQgdG8gcmVwcm9kdWNlLAp0cmFuc2xhdGUgKGFzIGRlZmluZWQgYmVsb3cpLCBhbmQvb3IgZGlzdHJpYnV0ZSB5b3VyIHN1Ym1pc3Npb24gKGluY2x1ZGluZwp0aGUgYWJzdHJhY3QpIHdvcmxkd2lkZSBpbiBwcmludCBhbmQgZWxlY3Ryb25pYyBmb3JtYXQgYW5kIGluIGFueSBtZWRpdW0sCmluY2x1ZGluZyBidXQgbm90IGxpbWl0ZWQgdG8gYXVkaW8gb3IgdmlkZW8uCgpZb3UgYWdyZWUgdGhhdCBEU1UgbWF5LCB3aXRob3V0IGNoYW5naW5nIHRoZSBjb250ZW50LCB0cmFuc2xhdGUgdGhlCnN1Ym1pc3Npb24gdG8gYW55IG1lZGl1bSBvciBmb3JtYXQgZm9yIHRoZSBwdXJwb3NlIG9mIHByZXNlcnZhdGlvbi4KCllvdSBhbHNvIGFncmVlIHRoYXQgRFNVIG1heSBrZWVwIG1vcmUgdGhhbiBvbmUgY29weSBvZiB0aGlzIHN1Ym1pc3Npb24gZm9yCnB1cnBvc2VzIG9mIHNlY3VyaXR5LCBiYWNrLXVwIGFuZCBwcmVzZXJ2YXRpb24uCgpZb3UgcmVwcmVzZW50IHRoYXQgdGhlIHN1Ym1pc3Npb24gaXMgeW91ciBvcmlnaW5hbCB3b3JrLCBhbmQgdGhhdCB5b3UgaGF2ZQp0aGUgcmlnaHQgdG8gZ3JhbnQgdGhlIHJpZ2h0cyBjb250YWluZWQgaW4gdGhpcyBsaWNlbnNlLiBZb3UgYWxzbyByZXByZXNlbnQKdGhhdCB5b3VyIHN1Ym1pc3Npb24gZG9lcyBub3QsIHRvIHRoZSBiZXN0IG9mIHlvdXIga25vd2xlZGdlLCBpbmZyaW5nZSB1cG9uCmFueW9uZSdzIGNvcHlyaWdodC4KCklmIHRoZSBzdWJtaXNzaW9uIGNvbnRhaW5zIG1hdGVyaWFsIGZvciB3aGljaCB5b3UgZG8gbm90IGhvbGQgY29weXJpZ2h0LAp5b3UgcmVwcmVzZW50IHRoYXQgeW91IGhhdmUgb2J0YWluZWQgdGhlIHVucmVzdHJpY3RlZCBwZXJtaXNzaW9uIG9mIHRoZQpjb3B5cmlnaHQgb3duZXIgdG8gZ3JhbnQgRFNVIHRoZSByaWdodHMgcmVxdWlyZWQgYnkgdGhpcyBsaWNlbnNlLCBhbmQgdGhhdApzdWNoIHRoaXJkLXBhcnR5IG93bmVkIG1hdGVyaWFsIGlzIGNsZWFybHkgaWRlbnRpZmllZCBhbmQgYWNrbm93bGVkZ2VkCndpdGhpbiB0aGUgdGV4dCBvciBjb250ZW50IG9mIHRoZSBzdWJtaXNzaW9uLgoKSUYgVEhFIFNVQk1JU1NJT04gSVMgQkFTRUQgVVBPTiBXT1JLIFRIQVQgSEFTIEJFRU4gU1BPTlNPUkVEIE9SIFNVUFBPUlRFRApCWSBBTiBBR0VOQ1kgT1IgT1JHQU5JWkFUSU9OIE9USEVSIFRIQU4gRFNVLCBZT1UgUkVQUkVTRU5UIFRIQVQgWU9VIEhBVkUKRlVMRklMTEVEIEFOWSBSSUdIVCBPRiBSRVZJRVcgT1IgT1RIRVIgT0JMSUdBVElPTlMgUkVRVUlSRUQgQlkgU1VDSApDT05UUkFDVCBPUiBBR1JFRU1FTlQuCgpEU1Ugd2lsbCBjbGVhcmx5IGlkZW50aWZ5IHlvdXIgbmFtZShzKSBhcyB0aGUgYXV0aG9yKHMpIG9yIG93bmVyKHMpIG9mIHRoZQpzdWJtaXNzaW9uLCBhbmQgd2lsbCBub3QgbWFrZSBhbnkgYWx0ZXJhdGlvbiwgb3RoZXIgdGhhbiBhcyBhbGxvd2VkIGJ5IHRoaXMKbGljZW5zZSwgdG8geW91ciBzdWJtaXNzaW9uLgo=Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-07-05T18:55:15Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS)
title An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS)
spellingShingle An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS)
Dalmazio, Ilza
paracetamol
advanced oxidation process
GC-MS
title_short An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS)
title_full An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS)
title_fullStr An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS)
title_full_unstemmed An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS)
title_sort An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS)
author Dalmazio, Ilza
author_facet Dalmazio, Ilza
Alves, Tânia Maria Almeida
Augusti, Rodinei
author_role author
author2 Alves, Tânia Maria Almeida
Augusti, Rodinei
author2_role author
author
dc.contributor.author.fl_str_mv Dalmazio, Ilza
Alves, Tânia Maria Almeida
Augusti, Rodinei
dc.subject.en.pt_BR.fl_str_mv paracetamol
advanced oxidation process
GC-MS
topic paracetamol
advanced oxidation process
GC-MS
description CONSELHO NACIONAL DE DESENVOLVIMENTO CIENTÍFICO E TECNOLÓGICO
publishDate 2008
dc.date.issued.fl_str_mv 2008
dc.date.accessioned.fl_str_mv 2022-07-05T18:55:14Z
dc.date.available.fl_str_mv 2022-07-05T18:55:14Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv DALMÁZIO, Ilza; ALVES, Tânia Maria Almeida; AUGUSTI, Rodinei. An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS). J. Braz. Chem. Soc., v. 19, n.1, p. 81-88, 2008. doi.org/10.1590/S0103-50532008000100013
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/53643
dc.identifier.issn.pt_BR.fl_str_mv 103-5053
dc.identifier.doi.none.fl_str_mv 10.1590/S0103-50532008000100013
identifier_str_mv DALMÁZIO, Ilza; ALVES, Tânia Maria Almeida; AUGUSTI, Rodinei. An appraisal on the degradation of paracetamol by TiO2/UV system in aqueous medium. Product identification by gas chromatography-mass spectrometry (GC-MS). J. Braz. Chem. Soc., v. 19, n.1, p. 81-88, 2008. doi.org/10.1590/S0103-50532008000100013
103-5053
10.1590/S0103-50532008000100013
url https://www.arca.fiocruz.br/handle/icict/53643
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
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reponame_str Repositório Institucional da FIOCRUZ (ARCA)
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