Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2018 |
| Outros Autores: | , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/27865 |
Resumo: | Universidade Regional de Blumenau, SC, Brasil. |
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Boeder, Ariela MaínaTenfen, AdrielliSiebert, Diogo AlexandreAlmeida, Camila Leandra de BuenoFirmo, Cláudia Rafaela MarquesScharf, Dilamara RivaMicke, Gustavo AmadeuSiminionatto, Edésio LuísCordova, Caio Maurício Mendes deGuedes, Alessandro2018-08-06T12:54:47Z2018-08-06T12:54:47Z2018BOEDER, Ariela Maína et al. Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin. Revista Fitos, Rio de Janeiro, v. 12, n. 2, p. 110-116, jul. 2018.https://www.arca.fiocruz.br/handle/icict/2786510.5935/2446-4775.201800102496-4775engFundação Oswaldo Cruz. Farmanguinhos. Núcleo de Gestão em Biodiversidade e Saúde.Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumininfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Regional de Blumenau, SC, Brasil.Instituto Educacional de Santa Catarina. Faculdade Jangada. Departamento de Ciências Farmacêuticas. Jaraguá do Sul, SC, Brasil.Universidade Federal de Santa Catarina. Departamento de Química. Campus Trindade. Florianópolis, SC, Brasil.Fundação Universidade Regional de Blumenau. Departamento de Ciências Farmacêuticas. Blumenau, SC, Brasil.Fundação Universidade Regional de Blumenau. Campus 3. Blumenau, SC, Brasil.Fundação Universidade Regional de Blumenau. Laboratório de Cromatografia. Blumenau, SC, Brasil.Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Departamento de Química. Florianópolis, SC, Brasil.Fundação Universidade Regional de Blumenau. Campus 3. Blumenau, SC, Brasil.Fundação Universidade Regional de Blumenau. Departamento de Ciências Farmacêuticas. Blumenau, SC, Brasil.Fundação Universidade Regional de Blumenau. Departamento de Ciências Farmacêuticas. Blumenau, SC, Brasil.Curcuma longa (saffron) is widely used in Western cuisine and its consumption is associated to the prevention and control of various diseases. Nevertheless, there no report on its antibacterial activity against mycoplasma strains. Thus, the present study aims to evaluate the antibacterial activity of C. longa and the curcumin against strains of mycoplasma. The rhizomes of C. longa were submitted to different processes of conservation followed by maceration to obtain ethanolic and acetonic extracts, and decoction to obtain aqueous extracts. The extracts were analyzed by high-performance liquid chromatography coupled to an ultraviolet detector (HPLC-UV) to quantify curcumin. Anti-mycoplasma activity of the extracts and curcumin were evaluated using a broth microdilution technique to determine the minimum inhibitory concentration (MIC). The best activity was observed in the ethanolic and acetonic extracts, which had the higher curcumin content, indicating a relationship between the presence of this compound and the anti-mycoplasmatic activity.CurcumaCurcuminAnti-bacterial ActivityMycoplasmainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/27865/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALariela_maina_boeder_et_all.pdfapplication/pdf117405https://www.arca.fiocruz.br/bitstream/icict/27865/2/ariela_maina_boeder_et_all.pdf3d686c307b135133f6fd0d92adf82c14MD52TEXTariela_maina_boeder_et_all.pdf.txtariela_maina_boeder_et_all.pdf.txtExtracted texttext/plain21543https://www.arca.fiocruz.br/bitstream/icict/27865/3/ariela_maina_boeder_et_all.pdf.txt3048e1cbecbae2c86e43105973678a0bMD53icict/278652020-03-25 23:20:27.747oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352020-03-26T02:20:27Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false |
| dc.title.pt_BR.fl_str_mv |
Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin |
| title |
Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin |
| spellingShingle |
Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin Boeder, Ariela Maína Curcuma Curcumin Anti-bacterial Activity Mycoplasma |
| title_short |
Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin |
| title_full |
Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin |
| title_fullStr |
Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin |
| title_full_unstemmed |
Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin |
| title_sort |
Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin |
| author |
Boeder, Ariela Maína |
| author_facet |
Boeder, Ariela Maína Tenfen, Adrielli Siebert, Diogo Alexandre Almeida, Camila Leandra de Bueno Firmo, Cláudia Rafaela Marques Scharf, Dilamara Riva Micke, Gustavo Amadeu Siminionatto, Edésio Luís Cordova, Caio Maurício Mendes de Guedes, Alessandro |
| author_role |
author |
| author2 |
Tenfen, Adrielli Siebert, Diogo Alexandre Almeida, Camila Leandra de Bueno Firmo, Cláudia Rafaela Marques Scharf, Dilamara Riva Micke, Gustavo Amadeu Siminionatto, Edésio Luís Cordova, Caio Maurício Mendes de Guedes, Alessandro |
| author2_role |
author author author author author author author author author |
| dc.contributor.author.fl_str_mv |
Boeder, Ariela Maína Tenfen, Adrielli Siebert, Diogo Alexandre Almeida, Camila Leandra de Bueno Firmo, Cláudia Rafaela Marques Scharf, Dilamara Riva Micke, Gustavo Amadeu Siminionatto, Edésio Luís Cordova, Caio Maurício Mendes de Guedes, Alessandro |
| dc.subject.en.pt_BR.fl_str_mv |
Curcuma Curcumin Anti-bacterial Activity Mycoplasma |
| topic |
Curcuma Curcumin Anti-bacterial Activity Mycoplasma |
| description |
Universidade Regional de Blumenau, SC, Brasil. |
| publishDate |
2018 |
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2018-08-06T12:54:47Z |
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2018-08-06T12:54:47Z |
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2018 |
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BOEDER, Ariela Maína et al. Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin. Revista Fitos, Rio de Janeiro, v. 12, n. 2, p. 110-116, jul. 2018. |
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https://www.arca.fiocruz.br/handle/icict/27865 |
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10.5935/2446-4775.20180010 |
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2496-4775 |
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BOEDER, Ariela Maína et al. Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin. Revista Fitos, Rio de Janeiro, v. 12, n. 2, p. 110-116, jul. 2018. 10.5935/2446-4775.20180010 2496-4775 |
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Fundação Oswaldo Cruz. Farmanguinhos. Núcleo de Gestão em Biodiversidade e Saúde. |
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Fundação Oswaldo Cruz. Farmanguinhos. Núcleo de Gestão em Biodiversidade e Saúde. |
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