Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin

Detalhes bibliográficos
Autor(a) principal: Boeder, Ariela Maína
Data de Publicação: 2018
Outros Autores: Tenfen, Adrielli, Siebert, Diogo Alexandre, Almeida, Camila Leandra de Bueno, Firmo, Cláudia Rafaela Marques, Scharf, Dilamara Riva, Micke, Gustavo Amadeu, Siminionatto, Edésio Luís, Cordova, Caio Maurício Mendes de, Guedes, Alessandro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/27865
Resumo: Universidade Regional de Blumenau, SC, Brasil.
id CRUZ_ecbfc86d2c01ca6f00ee449f36529d7b
oai_identifier_str oai:www.arca.fiocruz.br:icict/27865
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Boeder, Ariela MaínaTenfen, AdrielliSiebert, Diogo AlexandreAlmeida, Camila Leandra de BuenoFirmo, Cláudia Rafaela MarquesScharf, Dilamara RivaMicke, Gustavo AmadeuSiminionatto, Edésio LuísCordova, Caio Maurício Mendes deGuedes, Alessandro2018-08-06T12:54:47Z2018-08-06T12:54:47Z2018BOEDER, Ariela Maína et al. Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin. Revista Fitos, Rio de Janeiro, v. 12, n. 2, p. 110-116, jul. 2018.https://www.arca.fiocruz.br/handle/icict/2786510.5935/2446-4775.201800102496-4775engFundação Oswaldo Cruz. Farmanguinhos. Núcleo de Gestão em Biodiversidade e Saúde.Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumininfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade Regional de Blumenau, SC, Brasil.Instituto Educacional de Santa Catarina. Faculdade Jangada. Departamento de Ciências Farmacêuticas. Jaraguá do Sul, SC, Brasil.Universidade Federal de Santa Catarina. Departamento de Química. Campus Trindade. Florianópolis, SC, Brasil.Fundação Universidade Regional de Blumenau. Departamento de Ciências Farmacêuticas. Blumenau, SC, Brasil.Fundação Universidade Regional de Blumenau. Campus 3. Blumenau, SC, Brasil.Fundação Universidade Regional de Blumenau. Laboratório de Cromatografia. Blumenau, SC, Brasil.Universidade Federal de Santa Catarina. Centro de Ciências Físicas e Matemáticas. Departamento de Química. Florianópolis, SC, Brasil.Fundação Universidade Regional de Blumenau. Campus 3. Blumenau, SC, Brasil.Fundação Universidade Regional de Blumenau. Departamento de Ciências Farmacêuticas. Blumenau, SC, Brasil.Fundação Universidade Regional de Blumenau. Departamento de Ciências Farmacêuticas. Blumenau, SC, Brasil.Curcuma longa (saffron) is widely used in Western cuisine and its consumption is associated to the prevention and control of various diseases. Nevertheless, there no report on its antibacterial activity against mycoplasma strains. Thus, the present study aims to evaluate the antibacterial activity of C. longa and the curcumin against strains of mycoplasma. The rhizomes of C. longa were submitted to different processes of conservation followed by maceration to obtain ethanolic and acetonic extracts, and decoction to obtain aqueous extracts. The extracts were analyzed by high-performance liquid chromatography coupled to an ultraviolet detector (HPLC-UV) to quantify curcumin. Anti-mycoplasma activity of the extracts and curcumin were evaluated using a broth microdilution technique to determine the minimum inhibitory concentration (MIC). The best activity was observed in the ethanolic and acetonic extracts, which had the higher curcumin content, indicating a relationship between the presence of this compound and the anti-mycoplasmatic activity.CurcumaCurcuminAnti-bacterial ActivityMycoplasmainfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/27865/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALariela_maina_boeder_et_all.pdfapplication/pdf117405https://www.arca.fiocruz.br/bitstream/icict/27865/2/ariela_maina_boeder_et_all.pdf3d686c307b135133f6fd0d92adf82c14MD52TEXTariela_maina_boeder_et_all.pdf.txtariela_maina_boeder_et_all.pdf.txtExtracted texttext/plain21543https://www.arca.fiocruz.br/bitstream/icict/27865/3/ariela_maina_boeder_et_all.pdf.txt3048e1cbecbae2c86e43105973678a0bMD53icict/278652020-03-25 23:20:27.747oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352020-03-26T02:20:27Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin
title Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin
spellingShingle Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin
Boeder, Ariela Maína
Curcuma
Curcumin
Anti-bacterial Activity
Mycoplasma
title_short Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin
title_full Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin
title_fullStr Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin
title_full_unstemmed Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin
title_sort Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin
author Boeder, Ariela Maína
author_facet Boeder, Ariela Maína
Tenfen, Adrielli
Siebert, Diogo Alexandre
Almeida, Camila Leandra de Bueno
Firmo, Cláudia Rafaela Marques
Scharf, Dilamara Riva
Micke, Gustavo Amadeu
Siminionatto, Edésio Luís
Cordova, Caio Maurício Mendes de
Guedes, Alessandro
author_role author
author2 Tenfen, Adrielli
Siebert, Diogo Alexandre
Almeida, Camila Leandra de Bueno
Firmo, Cláudia Rafaela Marques
Scharf, Dilamara Riva
Micke, Gustavo Amadeu
Siminionatto, Edésio Luís
Cordova, Caio Maurício Mendes de
Guedes, Alessandro
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Boeder, Ariela Maína
Tenfen, Adrielli
Siebert, Diogo Alexandre
Almeida, Camila Leandra de Bueno
Firmo, Cláudia Rafaela Marques
Scharf, Dilamara Riva
Micke, Gustavo Amadeu
Siminionatto, Edésio Luís
Cordova, Caio Maurício Mendes de
Guedes, Alessandro
dc.subject.en.pt_BR.fl_str_mv Curcuma
Curcumin
Anti-bacterial Activity
Mycoplasma
topic Curcuma
Curcumin
Anti-bacterial Activity
Mycoplasma
description Universidade Regional de Blumenau, SC, Brasil.
publishDate 2018
dc.date.accessioned.fl_str_mv 2018-08-06T12:54:47Z
dc.date.available.fl_str_mv 2018-08-06T12:54:47Z
dc.date.issued.fl_str_mv 2018
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv BOEDER, Ariela Maína et al. Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin. Revista Fitos, Rio de Janeiro, v. 12, n. 2, p. 110-116, jul. 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/27865
dc.identifier.doi.pt_BR.fl_str_mv 10.5935/2446-4775.20180010
dc.identifier.eissn.pt_BR.fl_str_mv 2496-4775
identifier_str_mv BOEDER, Ariela Maína et al. Anti-mycoplasma activity of Curcuma longa extracts and an isolated compound, the curcumin. Revista Fitos, Rio de Janeiro, v. 12, n. 2, p. 110-116, jul. 2018.
10.5935/2446-4775.20180010
2496-4775
url https://www.arca.fiocruz.br/handle/icict/27865
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Farmanguinhos. Núcleo de Gestão em Biodiversidade e Saúde.
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Farmanguinhos. Núcleo de Gestão em Biodiversidade e Saúde.
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/27865/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/27865/2/ariela_maina_boeder_et_all.pdf
https://www.arca.fiocruz.br/bitstream/icict/27865/3/ariela_maina_boeder_et_all.pdf.txt
bitstream.checksum.fl_str_mv 8a4605be74aa9ea9d79846c1fba20a33
3d686c307b135133f6fd0d92adf82c14
3048e1cbecbae2c86e43105973678a0b
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1813008912152002560