Impact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trial
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2018 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/25985 |
Resumo: | Fundação de Amparo à Pesquisa do Estado da Bahia (Programa Primeiros Projetos Nº 160/2003). |
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Peleteiro, Thaís SilvaOliveira, Evelin SantosConceição, Elisabete LopesSampaio, Francisco NascimentoNeves, Neuza Maria AlcântaraMendes, Carlos Mauricio CardealBessa, Theolis Costa Barbosa2018-04-20T16:17:43Z2018-04-20T16:17:43Z2018PELETEIRO, T. S. et al. Impact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trial. Revista da Sociedade Brasileira de Medicina Tropical, v. 51, n. 1, p. 94-98, 2018.0037-8682https://www.arca.fiocruz.br/handle/icict/2598510.1590/0037-8682-0081-2017Fundação de Amparo à Pesquisa do Estado da Bahia (Programa Primeiros Projetos Nº 160/2003).Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, BrasilFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, BrasilFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, BrasilUniversidade Federal da Bahia. Hospital Universitário Prof. Edgar Santos. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, BrasilUniversidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, BrasilFundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Ciências da Saúde. Salvador, BA, Brasil / Rede Brasileira de Pesquisa em Tuberculose, Rio de Janeiro, RJ, BrasilBacille Calmette-Guérin (BCG) downmodulates allergen-specific IgE levels and prevents other atopic responses in experimental models but fails to protect against respiratory allergies. Human responsiveness to BCG is variable and may interfere with protection. Methods: Multivariate models were evaluated to test the possible effect of responsiveness (assessed by IFN-γ production) to BCG revaccination on the modulation of total and allergen-specific serum IgE levels in healthy volunteers participating in a randomized controlled trial. Results: Serum total or Derp-specific IgE levels did not change regardless of the increase in IFN-γ levels. Conclusions: BCG responsiveness does not affect protection against atopy.engSociedade Brasileira de Medicina TropicalAlergiaAtopiaVacina contra a tuberculoseAllergyAtopyTuberculosis vaccineImpact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trialinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/25985/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALPeleteiro T Impact of Bacille Calmette-Guérin ....pdfPeleteiro T Impact of Bacille Calmette-Guérin ....pdfapplication/pdf1175574https://www.arca.fiocruz.br/bitstream/icict/25985/2/Peleteiro%20T%20Impact%20of%20Bacille%20Calmette-Gu%c3%a9rin%20....pdf2982b238a73d0d4a2965e2c7870786e9MD52TEXTPeleteiro T Impact of Bacille Calmette-Guérin 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| dc.title.pt_BR.fl_str_mv |
Impact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trial |
| title |
Impact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trial |
| spellingShingle |
Impact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trial Peleteiro, Thaís Silva Alergia Atopia Vacina contra a tuberculose Allergy Atopy Tuberculosis vaccine |
| title_short |
Impact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trial |
| title_full |
Impact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trial |
| title_fullStr |
Impact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trial |
| title_full_unstemmed |
Impact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trial |
| title_sort |
Impact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trial |
| author |
Peleteiro, Thaís Silva |
| author_facet |
Peleteiro, Thaís Silva Oliveira, Evelin Santos Conceição, Elisabete Lopes Sampaio, Francisco Nascimento Neves, Neuza Maria Alcântara Mendes, Carlos Mauricio Cardeal Bessa, Theolis Costa Barbosa |
| author_role |
author |
| author2 |
Oliveira, Evelin Santos Conceição, Elisabete Lopes Sampaio, Francisco Nascimento Neves, Neuza Maria Alcântara Mendes, Carlos Mauricio Cardeal Bessa, Theolis Costa Barbosa |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Peleteiro, Thaís Silva Oliveira, Evelin Santos Conceição, Elisabete Lopes Sampaio, Francisco Nascimento Neves, Neuza Maria Alcântara Mendes, Carlos Mauricio Cardeal Bessa, Theolis Costa Barbosa |
| dc.subject.other.pt_BR.fl_str_mv |
Alergia Atopia Vacina contra a tuberculose |
| topic |
Alergia Atopia Vacina contra a tuberculose Allergy Atopy Tuberculosis vaccine |
| dc.subject.en.pt_BR.fl_str_mv |
Allergy Atopy Tuberculosis vaccine |
| description |
Fundação de Amparo à Pesquisa do Estado da Bahia (Programa Primeiros Projetos Nº 160/2003). |
| publishDate |
2018 |
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2018-04-20T16:17:43Z |
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2018-04-20T16:17:43Z |
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2018 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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PELETEIRO, T. S. et al. Impact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trial. Revista da Sociedade Brasileira de Medicina Tropical, v. 51, n. 1, p. 94-98, 2018. |
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https://www.arca.fiocruz.br/handle/icict/25985 |
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0037-8682 |
| dc.identifier.doi.none.fl_str_mv |
10.1590/0037-8682-0081-2017 |
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PELETEIRO, T. S. et al. Impact of Bacille Calmette-Guérin revaccination on serum IgE levels in a randomized controlled trial. Revista da Sociedade Brasileira de Medicina Tropical, v. 51, n. 1, p. 94-98, 2018. 0037-8682 10.1590/0037-8682-0081-2017 |
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Sociedade Brasileira de Medicina Tropical |
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Sociedade Brasileira de Medicina Tropical |
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