Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains

Detalhes bibliográficos
Autor(a) principal: Freitas, Priscilla Ramos
Data de Publicação: 2020
Outros Autores: Araújo, Ana Carolina Justino de, Barbosa, Cristina Rodrigues dos Santos, Muniz, Debora Feitosa, Rocha, Janaina Esmeraldo, Araújo Neto, José Bezerra de, Silva, Maria Milene Costa da, Pereira, Raimundo Luiz Silva, Silva, Luiz Everson da, Amaral, Wanderlei do, Deschamps, Cicero, Tintino, Saulo Relison, Ribeiro Filho, Jaime, Coutinho, Henrique Douglas Melo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/41297
Resumo: Regional University of Cariri. Laboratory of Microbiology and Molecular Biology. Cariri, CE, Brazil.
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spelling Freitas, Priscilla RamosAraújo, Ana Carolina Justino deBarbosa, Cristina Rodrigues dos SantosMuniz, Debora FeitosaRocha, Janaina EsmeraldoAraújo Neto, José Bezerra deSilva, Maria Milene Costa daPereira, Raimundo Luiz SilvaSilva, Luiz Everson daAmaral, Wanderlei doDeschamps, CiceroTintino, Saulo RelisonRibeiro Filho, JaimeCoutinho, Henrique Douglas Melo2020-05-19T11:35:10Z2020-05-19T11:35:10Z2020FREITAS, Priscilla Ramos et al. Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains. Microbial Pathogenesis, v. 145, 2020.0882-4010https://www.arca.fiocruz.br/handle/icict/4129710.1016/j.micpath.2020.104223engElsevierBaccharis coridifoliaEscherichia coliPseudomonas aeruginosaStaphylococcus aureusAgentes antibacterianosÓleos essenciaisBaccharis coridifoliaEscherichia coliPseudomonas aeruginosaStaphylococcus aureusAntibacterial agentsEssential oilsCharacterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strainsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleRegional University of Cariri. Laboratory of Microbiology and Molecular Biology. Cariri, CE, Brazil.Regional University of Cariri. Laboratory of Microbiology and Molecular Biology. Cariri, CE, Brazil.Regional University of Cariri. Laboratory of Bioprospecting of Semiarid and Alternative Methods. Cariri, CE, Brazil.Regional University of Cariri. Laboratory of Microbiology and Molecular Biology. Cariri, CE, Brazil.Regional University of Cariri. Laboratory of Microbiology and Molecular Biology. Cariri, CE, Brazil.Regional University of Cariri. Laboratory of Microbiology and Molecular Biology. Cariri, CE, Brazil.Regional University of Cariri. Laboratory of Microbiology and Molecular Biology. Cariri, CE, Brazil.Regional University of Cariri. Laboratory of Simulations and Molecular Spectroscopy. Cariri, CE, Brazil.Federal University of Parana. Paraná, SC, Brazil.Federal University of Parana. Paraná, SC, Brazil.Federal University of Parana. Paraná, SC, Brazil..Regional University of Cariri. Laboratory of Microbiology and Molecular Biology. Cariri, CE, Brazil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Regional University of Cariri. Laboratory of Microbiology and Molecular Biology. Cariri, CE, Brazil.Essential oils are secondary metabolites with immense pharmacological potential.These substances are abundantly produced by plants of the family Asteraceae, such as Baccharis coridifolia. Previous studies have demonstrated that this species has pharmacological properties that make it a promising source of new antibacterial agents. Therefore, the present study aimed to evaluate the antibacterial and antibiotic-modulating activity of Baccharis coridifolia essential oil against multidrug-resistant (MDR) strains. The phytochemical analysis was carried out by gas chromatography coupled to Mass Spectroscopy (GC/MS), and realized the Minimum Inhibitory Concentation (MIC) and antibiotic-modulation from the microdilution method in 96-well plates. It was revealed the presence of germacrene D (23.7%), bicyclogermacrene (17.1%), and (E)-caryophyllene (8.4%) as major components. The minimum inhibitory concentration of essential oil against strains of Pseudomonas aeruginosa (512 μg/mL) and Staphylococcus aureus (128 μg/mL) demonstrated clinically relevant antibacterial activity. In addition, the combination of subinhibitory doses of the oil with conventional antibiotics showed synergism, indicating potentiation of the antibacterial effect. In conclusion, the essential oil of Baccharis coridifolia (EOBc) presented antibacterial and antibiotic-modulating activities that place this species as a source of molecules useful in the fight against bacterial resistance.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/41297/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALFreitas P Ramos Characterization....pdfFreitas P Ramos Characterization....pdfapplication/pdf449782https://www.arca.fiocruz.br/bitstream/icict/41297/2/Freitas%20P%20Ramos%20Characterization....pdfd6648ed7c06c93bdf63b0860e07c0815MD52TEXTFreitas P Ramos Characterization....pdf.txtFreitas P Ramos Characterization....pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains
title Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains
spellingShingle Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains
Freitas, Priscilla Ramos
Baccharis coridifolia
Escherichia coli
Pseudomonas aeruginosa
Staphylococcus aureus
Agentes antibacterianos
Óleos essenciais
Baccharis coridifolia
Escherichia coli
Pseudomonas aeruginosa
Staphylococcus aureus
Antibacterial agents
Essential oils
title_short Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains
title_full Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains
title_fullStr Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains
title_full_unstemmed Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains
title_sort Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains
author Freitas, Priscilla Ramos
author_facet Freitas, Priscilla Ramos
Araújo, Ana Carolina Justino de
Barbosa, Cristina Rodrigues dos Santos
Muniz, Debora Feitosa
Rocha, Janaina Esmeraldo
Araújo Neto, José Bezerra de
Silva, Maria Milene Costa da
Pereira, Raimundo Luiz Silva
Silva, Luiz Everson da
Amaral, Wanderlei do
Deschamps, Cicero
Tintino, Saulo Relison
Ribeiro Filho, Jaime
Coutinho, Henrique Douglas Melo
author_role author
author2 Araújo, Ana Carolina Justino de
Barbosa, Cristina Rodrigues dos Santos
Muniz, Debora Feitosa
Rocha, Janaina Esmeraldo
Araújo Neto, José Bezerra de
Silva, Maria Milene Costa da
Pereira, Raimundo Luiz Silva
Silva, Luiz Everson da
Amaral, Wanderlei do
Deschamps, Cicero
Tintino, Saulo Relison
Ribeiro Filho, Jaime
Coutinho, Henrique Douglas Melo
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Freitas, Priscilla Ramos
Araújo, Ana Carolina Justino de
Barbosa, Cristina Rodrigues dos Santos
Muniz, Debora Feitosa
Rocha, Janaina Esmeraldo
Araújo Neto, José Bezerra de
Silva, Maria Milene Costa da
Pereira, Raimundo Luiz Silva
Silva, Luiz Everson da
Amaral, Wanderlei do
Deschamps, Cicero
Tintino, Saulo Relison
Ribeiro Filho, Jaime
Coutinho, Henrique Douglas Melo
dc.subject.other.pt_BR.fl_str_mv Baccharis coridifolia
Escherichia coli
Pseudomonas aeruginosa
Staphylococcus aureus
Agentes antibacterianos
Óleos essenciais
topic Baccharis coridifolia
Escherichia coli
Pseudomonas aeruginosa
Staphylococcus aureus
Agentes antibacterianos
Óleos essenciais
Baccharis coridifolia
Escherichia coli
Pseudomonas aeruginosa
Staphylococcus aureus
Antibacterial agents
Essential oils
dc.subject.en.pt_BR.fl_str_mv Baccharis coridifolia
Escherichia coli
Pseudomonas aeruginosa
Staphylococcus aureus
Antibacterial agents
Essential oils
description Regional University of Cariri. Laboratory of Microbiology and Molecular Biology. Cariri, CE, Brazil.
publishDate 2020
dc.date.accessioned.fl_str_mv 2020-05-19T11:35:10Z
dc.date.available.fl_str_mv 2020-05-19T11:35:10Z
dc.date.issued.fl_str_mv 2020
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv FREITAS, Priscilla Ramos et al. Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains. Microbial Pathogenesis, v. 145, 2020.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/41297
dc.identifier.issn.pt_BR.fl_str_mv 0882-4010
dc.identifier.doi.none.fl_str_mv 10.1016/j.micpath.2020.104223
identifier_str_mv FREITAS, Priscilla Ramos et al. Characterization and antibacterial activity of the essential oil obtained from the leaves of Baccharis coridifolia DC against multiresistant strains. Microbial Pathogenesis, v. 145, 2020.
0882-4010
10.1016/j.micpath.2020.104223
url https://www.arca.fiocruz.br/handle/icict/41297
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
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