Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2020 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da FIOCRUZ (ARCA) |
| DOI: | 10.1371/journal.pone.0238932 |
| Texto Completo: | https://www.arca.fiocruz.br/handle/icict/44296 |
Resumo: | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001 (https://www.capes.gov.br). |
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Araújo, Lucas OliveiraNunes, Amélia Maria Pithon BorgesFerreira, Viviane MatosCardoso, Cristiane WanderleyFeitosa, Caroline AlvesReis, Mitermayer Galvão dosCampos, Leila Carvalho2020-11-03T12:07:28Z2020-11-03T12:07:28Z2020ARAÚJO, Lucas Oliveira et al. Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016. Plos One, p. 1-12, Sept. 2020.1932-6203https://www.arca.fiocruz.br/handle/icict/4429610.1371/journal.pone.0238932Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001 (https://www.capes.gov.br).Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Escola Bahiana de Medicina e Saúde. Salvador, BA, Brasil.Secretaria Municipal de Saúde. Salvador, BA, Brasil.Escola Bahiana de Medicina e Saúde. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil / Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, CO, United States of America.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.Pertussis, a severe respiratory infection caused by Bordetella pertussis, is distributed globally. Vaccination has been crucial to annual reductions in the number of cases. However, disease reemergence has occurred over the last decade in several countries, including Brazil. Here we describe the clinical and epidemiological aspects of suspected pertussis cases in Salvador, Brazil, and evaluate factors associated with case confirmation. This descriptive and retrospective study was conducted in the five hospitals in Salvador that reported the highest number of pertussis cases between 2011–2016. Demographic and clinical data were recorded for each patient. Bivariate analysis was performed to evaluate differences between groups (confirmed vs. unconfirmed cases) using Pearson’s Chi-square test or Fisher’s exact test. Results: Of 529 suspected pertussis cases, 29.7% (157/529) were confirmed by clinical, clinical-epidemiological or laboratory criteria, with clinical criteria most frequently applied (63.7%; 100/157). Unvaccinated individuals (43.3%; 68/157) were the most affected, followed by age groups 2–3 months (37.6%; 59/157) and <2 months (31.2%; 49/ 157). Overall, ≥50% of the confirmed cases presented a complete vaccination schedule. All investigated cases presented cough in association with one or more symptoms, especially paroxysmal cough (66.9%; 105/529) (p = 0.001) or cyanosis (66.2%; 104/529) (p<0.001). Our results indicate that pertussis occurred mainly in infants and unvaccinated individuals in Salvador, Brazil. The predominance of clinical criteria used to confirm suspected cases highlights the need for improvement in the laboratory tools used to perform rapid diagnosis. Fluctuations in infection prevalence demonstrate the importance of vaccination strategies in improving the control and prevention of pertussis.engPublic Library of ScienceCoquelucheVacina contra CoquelucheDiagnósticoEpidemiologiaPrevençãoBrasilWhooping CoughPertussis VaccineDiagnosticEpidemiologyPreventionBrazilClinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/44296/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALAraujo, Lucas de Oliveira Clinical....pdfAraujo, Lucas de Oliveira 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| dc.title.pt_BR.fl_str_mv |
Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016 |
| title |
Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016 |
| spellingShingle |
Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016 Araújo, Lucas Oliveira Coqueluche Vacina contra Coqueluche Diagnóstico Epidemiologia Prevenção Brasil Whooping Cough Pertussis Vaccine Diagnostic Epidemiology Prevention Brazil |
| title_short |
Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016 |
| title_full |
Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016 |
| title_fullStr |
Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016 |
| title_full_unstemmed |
Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016 |
| title_sort |
Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016 |
| author |
Araújo, Lucas Oliveira |
| author_facet |
Araújo, Lucas Oliveira Nunes, Amélia Maria Pithon Borges Ferreira, Viviane Matos Cardoso, Cristiane Wanderley Feitosa, Caroline Alves Reis, Mitermayer Galvão dos Campos, Leila Carvalho |
| author_role |
author |
| author2 |
Nunes, Amélia Maria Pithon Borges Ferreira, Viviane Matos Cardoso, Cristiane Wanderley Feitosa, Caroline Alves Reis, Mitermayer Galvão dos Campos, Leila Carvalho |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Araújo, Lucas Oliveira Nunes, Amélia Maria Pithon Borges Ferreira, Viviane Matos Cardoso, Cristiane Wanderley Feitosa, Caroline Alves Reis, Mitermayer Galvão dos Campos, Leila Carvalho |
| dc.subject.other.pt_BR.fl_str_mv |
Coqueluche Vacina contra Coqueluche Diagnóstico Epidemiologia Prevenção Brasil |
| topic |
Coqueluche Vacina contra Coqueluche Diagnóstico Epidemiologia Prevenção Brasil Whooping Cough Pertussis Vaccine Diagnostic Epidemiology Prevention Brazil |
| dc.subject.en.pt_BR.fl_str_mv |
Whooping Cough Pertussis Vaccine Diagnostic Epidemiology Prevention Brazil |
| description |
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - Brasil (CAPES) - Finance Code 001 (https://www.capes.gov.br). |
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2020 |
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2020-11-03T12:07:28Z |
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2020-11-03T12:07:28Z |
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2020 |
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info:eu-repo/semantics/article |
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ARAÚJO, Lucas Oliveira et al. Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016. Plos One, p. 1-12, Sept. 2020. |
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https://www.arca.fiocruz.br/handle/icict/44296 |
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1932-6203 |
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10.1371/journal.pone.0238932 |
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ARAÚJO, Lucas Oliveira et al. Clinical and epidemiological features of pertussis in Salvador, Brazil, 2011–2016. Plos One, p. 1-12, Sept. 2020. 1932-6203 10.1371/journal.pone.0238932 |
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