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spelling Oliveira, Juliane Fonseca deJorge, Daniel Cardoso PereiraVeiga, Rafael ValenteRodrigues, Moreno Magalhães de SouzaTorquato, Matheus FernandesSilva, Nívea Bispo daFiaccone, Rosemeire LeovigildoCardim, Luciana LobatoPereira, Felipe Augusto CardosoCastro, Caio Porto dePaiva, Aureliano Sancho SouzaAmad, Alan Alves SantanaLima, Ernesto Augusto Bueno da FonsecaSouza, Diego S.Pinho, Suani Tavares Rubim deRamos, Pablo Ivan PereiraAndrade, Roberto F. S.2021-03-03T13:30:47Z2021-03-03T13:30:47Z2021OLIVEIRA, Juliane Fonseca de et al. Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil. Nature Communications, v. 12, n. 333, p. 1-13, 12 Jan. 2021.2041-1723https://www.arca.fiocruz.br/handle/icict/4624010.1038/s41467-020-19798-32041-1723Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brazil (CAPES)—Finance Code 001International Cooperation grant (process number INT0002/2016) from BahiaResearch Foundation (FAPESB)National Institute of Science and Technology—Complex Systems from CNPq, Brazil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para Saúde. Salvador, BA, Brasil / Universidade do Porto. Faculdade de Ciências. Centro de Matemática. Departamento de Matemática. Porto, Portugal.Universidade Federal da Bahia. Instituto de Física. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para Saúde. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Fiocruz Rondônia. Porto Velho, RO, Brasil.Swansea University. College Of Engineering. Swansea, United Kingdom.Universidade Federal da Bahia. Instituto de Matemática e Estatística. Salvador, BA, Brasil.Universidade Federal da Bahia. Instituto de Matemática e Estatística. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para Saúde. Salvador, BA, Brasil.Universidade de São Paulo. Instituto de Física. São Paulo, SP, Brasil.Universidade Federal da Bahia. Instituto de Física. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para Saúde. Salvador, BA, Brasil.Swansea University. College Of Engineering. Swansea, United Kingdom.The University of Texas at Austin. Oden Institute for Computational Engineering and Sciences. Austin, TX, United States.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para Saúde. Salvador, BA, Brasil.Universidade Federal da Bahia. Instituto de Física. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para Saúde. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Centro de Integração de Dados e Conhecimentos para Saúde. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Física. Salvador, BA, Brasil.COVID-19 is affecting healthcare resources worldwide, with lower and middle-income countries being particularly disadvantaged to mitigate the challenges imposed by the disease, including the availability of a sufficient number of infirmary/ICU hospital beds, ventilators, and medical supplies. Here, we use mathematical modelling to study the dynamics of COVID19 in Bahia, a state in northeastern Brazil, considering the influences of asymptomatic/nondetected cases, hospitalizations, and mortality. The impacts of policies on the transmission rate were also examined. Our results underscore the difficulties in maintaining a fully operational health infrastructure amidst the pandemic. Lowering the transmission rate is paramount to this objective, but current local efforts, leading to a 36% decrease, remain insufficient to prevent systemic collapse at peak demand, which could be accomplished using periodic interventions. Non-detected cases contribute to a ∽55% increase in R0. Finally, we discuss our results in light of epidemiological data that became available after the initial analyses.engNature ResearchCOVID-19PandemiasRecursos em saúdeMortalidadeTransmissãoBrasilCOVID-19PandemicsHealthcare resourcesMortalityTransmissionBrazilMathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazilinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83097https://www.arca.fiocruz.br/bitstream/icict/46240/1/license.txt36b51ef91c52b5338d9d29ba0cc807bcMD51ORIGINALOliveira, Juliane F Mathematical....pdfOliveira, Juliane F Mathematical....pdfapplication/pdf1877738https://www.arca.fiocruz.br/bitstream/icict/46240/2/Oliveira%2c%20Juliane%20F%20Mathematical....pdf4e404c6da22570123ffb982f1e860685MD52TEXTOliveira, Juliane F 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dc.title.en.fl_str_mv Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil
title Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil
spellingShingle Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil
Oliveira, Juliane Fonseca de
COVID-19
Pandemias
Recursos em saúde
Mortalidade
Transmissão
Brasil
COVID-19
Pandemics
Healthcare resources
Mortality
Transmission
Brazil
title_short Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil
title_full Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil
title_fullStr Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil
title_full_unstemmed Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil
title_sort Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil
author Oliveira, Juliane Fonseca de
author_facet Oliveira, Juliane Fonseca de
Jorge, Daniel Cardoso Pereira
Veiga, Rafael Valente
Rodrigues, Moreno Magalhães de Souza
Torquato, Matheus Fernandes
Silva, Nívea Bispo da
Fiaccone, Rosemeire Leovigildo
Cardim, Luciana Lobato
Pereira, Felipe Augusto Cardoso
Castro, Caio Porto de
Paiva, Aureliano Sancho Souza
Amad, Alan Alves Santana
Lima, Ernesto Augusto Bueno da Fonseca
Souza, Diego S.
Pinho, Suani Tavares Rubim de
Ramos, Pablo Ivan Pereira
Andrade, Roberto F. S.
author_role author
author2 Jorge, Daniel Cardoso Pereira
Veiga, Rafael Valente
Rodrigues, Moreno Magalhães de Souza
Torquato, Matheus Fernandes
Silva, Nívea Bispo da
Fiaccone, Rosemeire Leovigildo
Cardim, Luciana Lobato
Pereira, Felipe Augusto Cardoso
Castro, Caio Porto de
Paiva, Aureliano Sancho Souza
Amad, Alan Alves Santana
Lima, Ernesto Augusto Bueno da Fonseca
Souza, Diego S.
Pinho, Suani Tavares Rubim de
Ramos, Pablo Ivan Pereira
Andrade, Roberto F. S.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira, Juliane Fonseca de
Jorge, Daniel Cardoso Pereira
Veiga, Rafael Valente
Rodrigues, Moreno Magalhães de Souza
Torquato, Matheus Fernandes
Silva, Nívea Bispo da
Fiaccone, Rosemeire Leovigildo
Cardim, Luciana Lobato
Pereira, Felipe Augusto Cardoso
Castro, Caio Porto de
Paiva, Aureliano Sancho Souza
Amad, Alan Alves Santana
Lima, Ernesto Augusto Bueno da Fonseca
Souza, Diego S.
Pinho, Suani Tavares Rubim de
Ramos, Pablo Ivan Pereira
Andrade, Roberto F. S.
dc.subject.other.pt_BR.fl_str_mv COVID-19
Pandemias
Recursos em saúde
Mortalidade
Transmissão
Brasil
topic COVID-19
Pandemias
Recursos em saúde
Mortalidade
Transmissão
Brasil
COVID-19
Pandemics
Healthcare resources
Mortality
Transmission
Brazil
dc.subject.en.en.fl_str_mv COVID-19
Pandemics
Healthcare resources
Mortality
Transmission
Brazil
description Coordenação de Aperfeiçoamento de Pessoal de Nível Superior—Brazil (CAPES)—Finance Code 001
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-03-03T13:30:47Z
dc.date.available.fl_str_mv 2021-03-03T13:30:47Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
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dc.identifier.citation.fl_str_mv OLIVEIRA, Juliane Fonseca de et al. Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil. Nature Communications, v. 12, n. 333, p. 1-13, 12 Jan. 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/46240
dc.identifier.issn.pt_BR.fl_str_mv 2041-1723
dc.identifier.doi.pt_BR.fl_str_mv 10.1038/s41467-020-19798-3
dc.identifier.eissn.pt_BR.fl_str_mv 2041-1723
identifier_str_mv OLIVEIRA, Juliane Fonseca de et al. Mathematical modeling of COVID-19 in 14.8 million individuals in Bahia, Brazil. Nature Communications, v. 12, n. 333, p. 1-13, 12 Jan. 2021.
2041-1723
10.1038/s41467-020-19798-3
url https://www.arca.fiocruz.br/handle/icict/46240
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