Understanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvement

Detalhes bibliográficos
Autor(a) principal: Silva, João Hermínio Martins da
Data de Publicação: 2015
Outros Autores: Figueiredo, Alexandre Bezerra Conde, Arissawa, Márcia
Tipo de documento: Artigo de conferência
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/28416
Resumo: Fundação Oswaldo Cruz. Fiocruz Ceará. Eusébio, CE, Brasil.
id CRUZ_f2d1d702ebac8b85524383015eedd803
oai_identifier_str oai:www.arca.fiocruz.br:icict/28416
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Silva, João Hermínio Martins daFigueiredo, Alexandre Bezerra CondeArissawa, Márcia2018-08-28T18:57:17Z2018-08-28T18:57:17Z2015SILVA, J. H. M. da; FIGUEIREDO, A. B. C.; ARISSAWA, M. Understanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvement. In: SEMINÁRIO ANUAL CIENTÍFICO E TECNOLÓGICO DE BIO-MANGUINHOS, 3., 2015, Rio de Janeiro. Anais... Rio de Janeiro: Bio-Manguinhos, 2015. p. 126-127.https://www.arca.fiocruz.br/handle/icict/2841610.35259/isi.sact.2015_28416engFiocruz/Instituto de Tecnologia em ImunobiológicosAnticorpos MonoclonaisAntígenos de Superfície da Hepatite BSimulação de Dinâmica MolecularSACTMonoclonal AntibodyHBsAgMolecular DynamicsAntígenos de Superfície da Hepatite BSimulação de Dinâmica MolecularUnderstanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvementinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObjectFundação Oswaldo Cruz. Fiocruz Ceará. Eusébio, CE, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/28416/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALIII SACT _ OTR11.pdfIII SACT _ OTR11.pdfapplication/pdf52669https://www.arca.fiocruz.br/bitstream/icict/28416/2/III%20SACT%20_%20OTR11.pdffe29c3e83dd849f77f61c1689fb15ebaMD52TEXTIII SACT _ OTR11.pdf.txtIII SACT _ OTR11.pdf.txtExtracted texttext/plain3208https://www.arca.fiocruz.br/bitstream/icict/28416/3/III%20SACT%20_%20OTR11.pdf.txtcc546b078e2315065fb55526b84b8efaMD53icict/284162023-04-26 17:04:04.707oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352023-04-26T20:04:04Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv Understanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvement
title Understanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvement
spellingShingle Understanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvement
Silva, João Hermínio Martins da
Anticorpos Monoclonais
Antígenos de Superfície da Hepatite B
Simulação de Dinâmica Molecular
SACT
Monoclonal Antibody
HBsAg
Molecular Dynamics
Antígenos de Superfície da Hepatite B
Simulação de Dinâmica Molecular
title_short Understanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvement
title_full Understanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvement
title_fullStr Understanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvement
title_full_unstemmed Understanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvement
title_sort Understanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvement
author Silva, João Hermínio Martins da
author_facet Silva, João Hermínio Martins da
Figueiredo, Alexandre Bezerra Conde
Arissawa, Márcia
author_role author
author2 Figueiredo, Alexandre Bezerra Conde
Arissawa, Márcia
author2_role author
author
dc.contributor.author.fl_str_mv Silva, João Hermínio Martins da
Figueiredo, Alexandre Bezerra Conde
Arissawa, Márcia
dc.subject.other.pt_BR.fl_str_mv Anticorpos Monoclonais
Antígenos de Superfície da Hepatite B
Simulação de Dinâmica Molecular
SACT
topic Anticorpos Monoclonais
Antígenos de Superfície da Hepatite B
Simulação de Dinâmica Molecular
SACT
Monoclonal Antibody
HBsAg
Molecular Dynamics
Antígenos de Superfície da Hepatite B
Simulação de Dinâmica Molecular
dc.subject.en.pt_BR.fl_str_mv Monoclonal Antibody
HBsAg
Molecular Dynamics
dc.subject.decs.pt_BR.fl_str_mv Antígenos de Superfície da Hepatite B
Simulação de Dinâmica Molecular
description Fundação Oswaldo Cruz. Fiocruz Ceará. Eusébio, CE, Brasil.
publishDate 2015
dc.date.issued.fl_str_mv 2015
dc.date.accessioned.fl_str_mv 2018-08-28T18:57:17Z
dc.date.available.fl_str_mv 2018-08-28T18:57:17Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/conferenceObject
format conferenceObject
status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, J. H. M. da; FIGUEIREDO, A. B. C.; ARISSAWA, M. Understanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvement. In: SEMINÁRIO ANUAL CIENTÍFICO E TECNOLÓGICO DE BIO-MANGUINHOS, 3., 2015, Rio de Janeiro. Anais... Rio de Janeiro: Bio-Manguinhos, 2015. p. 126-127.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/28416
dc.identifier.doi.none.fl_str_mv 10.35259/isi.sact.2015_28416
identifier_str_mv SILVA, J. H. M. da; FIGUEIREDO, A. B. C.; ARISSAWA, M. Understanding the interaction effects between a monoclonal antibody and HBsAg by molecular dynamics aiming the affinity mAb improvement. In: SEMINÁRIO ANUAL CIENTÍFICO E TECNOLÓGICO DE BIO-MANGUINHOS, 3., 2015, Rio de Janeiro. Anais... Rio de Janeiro: Bio-Manguinhos, 2015. p. 126-127.
10.35259/isi.sact.2015_28416
url https://www.arca.fiocruz.br/handle/icict/28416
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fiocruz/Instituto de Tecnologia em Imunobiológicos
publisher.none.fl_str_mv Fiocruz/Instituto de Tecnologia em Imunobiológicos
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/28416/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/28416/2/III%20SACT%20_%20OTR11.pdf
https://www.arca.fiocruz.br/bitstream/icict/28416/3/III%20SACT%20_%20OTR11.pdf.txt
bitstream.checksum.fl_str_mv 8a4605be74aa9ea9d79846c1fba20a33
fe29c3e83dd849f77f61c1689fb15eba
cc546b078e2315065fb55526b84b8efa
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1798324779487330304

Registros relacionados