The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis

Detalhes bibliográficos
Autor(a) principal: Rezende, Antonio M.
Data de Publicação: 2014
Outros Autores: Assis, Ludmila A., Nunes, Eduardo C., Costa Lima, Tamara D. da, Marchini, Fabrício Klerynton, Freire, Eden R., Reis, Christian R. S., Melo Neto, Osvaldo P. de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/22775
Resumo: Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil.
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spelling Rezende, Antonio M.Assis, Ludmila A.Nunes, Eduardo C.Costa Lima, Tamara D. daMarchini, Fabrício KleryntonFreire, Eden R.Reis, Christian R. S.Melo Neto, Osvaldo P. de2017-10-05T11:45:31Z2017-10-05T11:45:31Z2014REZENDE, Antonio M. et al. The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates – identification of conserved and divergent features based on orthologue analysis. BMC Genomics, v. 15, n. 1175, p. 1-19, 2014.1471-2164https://www.arca.fiocruz.br/handle/icict/2277510.1186/1471-2164-15-1175porBioMed CentralTrypanosomaProkaryotic Initiation Factor-3Protein BiosynthesisProtozoan InfectionsFactor 3 Procariótico de IniciaciónBiosíntesis de ProteínasInfecciones por ProtozoosFator de Iniciação 3 em ProcariotosBiossíntese de ProteínasInfecções por ProtozoáriosThe translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil.Fundação Oswaldo Cruz. Instituto Carlos Chagas. Laboratório de Genômica Funcional. Curitiba, PR, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil.Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil.The initiation of translation in eukaryotes is supported by the action of several eukaryotic Initiation Factors (eIFs). The largest of these is eIF3, comprising of up to thirteen polypeptides (eIF3a through eIF3m), involved in multiple stages of the initiation process. eIF3 has been better characterized from model organisms, but is poorly known from more diverged groups, including unicellular lineages represented by known human pathogens. These include the trypanosomatids (Trypanosoma and Leishmania) and other protists belonging to the taxonomic supergroup Excavata (Trichomonas and Giardia sp.).info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83084https://www.arca.fiocruz.br/bitstream/icict/22775/1/license.txt783568c2893d2e25a99990b126be1772MD51ORIGINALrezendethetranslatiook.pdfrezendethetranslatiook.pdfapplication/pdf4700948https://www.arca.fiocruz.br/bitstream/icict/22775/2/rezendethetranslatiook.pdf6fae434fe62b7e19e25d37db6f35c6dcMD52TEXTrezendethetranslatiook.pdf.txtrezendethetranslatiook.pdf.txtExtracted texttext/plain86758https://www.arca.fiocruz.br/bitstream/icict/22775/3/rezendethetranslatiook.pdf.txt545a5009fe62e25fe6c038d7dac80a41MD53icict/227752019-10-31 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dc.title.pt_BR.fl_str_mv The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
title The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
spellingShingle The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
Rezende, Antonio M.
Trypanosoma
Prokaryotic Initiation Factor-3
Protein Biosynthesis
Protozoan Infections
Factor 3 Procariótico de Iniciación
Biosíntesis de Proteínas
Infecciones por Protozoos
Fator de Iniciação 3 em Procariotos
Biossíntese de Proteínas
Infecções por Protozoários
title_short The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
title_full The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
title_fullStr The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
title_full_unstemmed The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
title_sort The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
author Rezende, Antonio M.
author_facet Rezende, Antonio M.
Assis, Ludmila A.
Nunes, Eduardo C.
Costa Lima, Tamara D. da
Marchini, Fabrício Klerynton
Freire, Eden R.
Reis, Christian R. S.
Melo Neto, Osvaldo P. de
author_role author
author2 Assis, Ludmila A.
Nunes, Eduardo C.
Costa Lima, Tamara D. da
Marchini, Fabrício Klerynton
Freire, Eden R.
Reis, Christian R. S.
Melo Neto, Osvaldo P. de
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Rezende, Antonio M.
Assis, Ludmila A.
Nunes, Eduardo C.
Costa Lima, Tamara D. da
Marchini, Fabrício Klerynton
Freire, Eden R.
Reis, Christian R. S.
Melo Neto, Osvaldo P. de
dc.subject.other.pt_BR.fl_str_mv Trypanosoma
topic Trypanosoma
Prokaryotic Initiation Factor-3
Protein Biosynthesis
Protozoan Infections
Factor 3 Procariótico de Iniciación
Biosíntesis de Proteínas
Infecciones por Protozoos
Fator de Iniciação 3 em Procariotos
Biossíntese de Proteínas
Infecções por Protozoários
dc.subject.en.pt_BR.fl_str_mv Prokaryotic Initiation Factor-3
Protein Biosynthesis
Protozoan Infections
dc.subject.es.pt_BR.fl_str_mv Factor 3 Procariótico de Iniciación
Biosíntesis de Proteínas
Infecciones por Protozoos
dc.subject.decs.pt_BR.fl_str_mv Fator de Iniciação 3 em Procariotos
Biossíntese de Proteínas
Infecções por Protozoários
description Fundação Oswaldo Cruz. Centro de Pesquisas Aggeu Magalhães. Recife, PE, Brasil.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2017-10-05T11:45:31Z
dc.date.available.fl_str_mv 2017-10-05T11:45:31Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.citation.fl_str_mv REZENDE, Antonio M. et al. The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates – identification of conserved and divergent features based on orthologue analysis. BMC Genomics, v. 15, n. 1175, p. 1-19, 2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/22775
dc.identifier.issn.pt_BR.fl_str_mv 1471-2164
dc.identifier.doi.none.fl_str_mv 10.1186/1471-2164-15-1175
identifier_str_mv REZENDE, Antonio M. et al. The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates – identification of conserved and divergent features based on orthologue analysis. BMC Genomics, v. 15, n. 1175, p. 1-19, 2014.
1471-2164
10.1186/1471-2164-15-1175
url https://www.arca.fiocruz.br/handle/icict/22775
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
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