The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis

Detalhes bibliográficos
Autor(a) principal: Rezende, Antonio M.
Data de Publicação: 2014
Outros Autores: Assis, Ludmila A., Nunes, Eduardo C., Lima, Tamara D. da Costa, Marchini, Fabricio K., Freire, Eden R., Reis, Christian R. S., Melo Neto, Osvaldo P. de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/23198
Resumo: Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
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spelling Rezende, Antonio M.Assis, Ludmila A.Nunes, Eduardo C.Lima, Tamara D. da CostaMarchini, Fabricio K.Freire, Eden R.Reis, Christian R. S.Melo Neto, Osvaldo P. de2017-11-16T11:39:41Z2017-11-16T11:39:41Z2014REZENDE, A. M. et al. The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis. BMC genomics, v. 15, p. 1175, 23 dez. 2014.1471-2164https://www.arca.fiocruz.br/handle/icict/2319810.1186/1471-2164-15-1175engEukaryotic Initiation Factor-3chemistryEukaryotic Initiation Factor-3geneticsTrichomonadidageneticsAnimalsComputational BiologyAmino Acid SequenceConserved SequenceGenetic VariationHumansFator de iniciação da traduçãosíntese de proteínaseIF3protozoáriosTranslation initiation factorProtein synthesiseIF3ProtozoaThe translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysisinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.The initiation of translation in eukaryotes is supported by the action of several eukaryotic Initiation Factors (eIFs). The largest of these is eIF3, comprising of up to thirteen polypeptides (eIF3a through eIF3m), involved in multiple stages of the initiation process. eIF3 has been better characterized from model organisms, but is poorly known from more diverged groups, including unicellular lineages represented by known human pathogens. These include the trypanosomatids (Trypanosoma and Leishmania) and other protists belonging to the taxonomic supergroup Excavata (Trichomonas and Giardia sp.).info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-83092https://www.arca.fiocruz.br/bitstream/icict/23198/1/license.txt447f2497af1ef5cf99b5c07f6fa18dceMD51ORIGINALart. The translation - Rezende.pdfart. 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dc.title.pt_BR.fl_str_mv The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
title The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
spellingShingle The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
Rezende, Antonio M.
Eukaryotic Initiation Factor-3
chemistry
Eukaryotic Initiation Factor-3
genetics
Trichomonadida
genetics
Animals
Computational Biology
Amino Acid Sequence
Conserved Sequence
Genetic Variation
Humans
Fator de iniciação da tradução
síntese de proteínas
eIF3
protozoários
Translation initiation factor
Protein synthesis
eIF3
Protozoa
title_short The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
title_full The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
title_fullStr The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
title_full_unstemmed The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
title_sort The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
author Rezende, Antonio M.
author_facet Rezende, Antonio M.
Assis, Ludmila A.
Nunes, Eduardo C.
Lima, Tamara D. da Costa
Marchini, Fabricio K.
Freire, Eden R.
Reis, Christian R. S.
Melo Neto, Osvaldo P. de
author_role author
author2 Assis, Ludmila A.
Nunes, Eduardo C.
Lima, Tamara D. da Costa
Marchini, Fabricio K.
Freire, Eden R.
Reis, Christian R. S.
Melo Neto, Osvaldo P. de
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Rezende, Antonio M.
Assis, Ludmila A.
Nunes, Eduardo C.
Lima, Tamara D. da Costa
Marchini, Fabricio K.
Freire, Eden R.
Reis, Christian R. S.
Melo Neto, Osvaldo P. de
dc.subject.mesh.pt_BR.fl_str_mv Eukaryotic Initiation Factor-3
chemistry
Eukaryotic Initiation Factor-3
genetics
Trichomonadida
genetics
Animals
Computational Biology
Amino Acid Sequence
Conserved Sequence
Genetic Variation
Humans
topic Eukaryotic Initiation Factor-3
chemistry
Eukaryotic Initiation Factor-3
genetics
Trichomonadida
genetics
Animals
Computational Biology
Amino Acid Sequence
Conserved Sequence
Genetic Variation
Humans
Fator de iniciação da tradução
síntese de proteínas
eIF3
protozoários
Translation initiation factor
Protein synthesis
eIF3
Protozoa
dc.subject.other.pt_BR.fl_str_mv Fator de iniciação da tradução
síntese de proteínas
eIF3
protozoários
dc.subject.en.pt_BR.fl_str_mv Translation initiation factor
Protein synthesis
eIF3
Protozoa
description Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
publishDate 2014
dc.date.issued.fl_str_mv 2014
dc.date.accessioned.fl_str_mv 2017-11-16T11:39:41Z
dc.date.available.fl_str_mv 2017-11-16T11:39:41Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv REZENDE, A. M. et al. The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis. BMC genomics, v. 15, p. 1175, 23 dez. 2014.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/23198
dc.identifier.issn.pt_BR.fl_str_mv 1471-2164
dc.identifier.doi.none.fl_str_mv 10.1186/1471-2164-15-1175
identifier_str_mv REZENDE, A. M. et al. The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis. BMC genomics, v. 15, p. 1175, 23 dez. 2014.
1471-2164
10.1186/1471-2164-15-1175
url https://www.arca.fiocruz.br/handle/icict/23198
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/23198/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/23198/2/art.%20The%20translation%20-%20Rezende.pdf
https://www.arca.fiocruz.br/bitstream/icict/23198/3/art.%20The%20translation%20-%20Rezende.pdf.txt
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repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
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