Experimental Canine Mucocutaneous Leishmaniasis (Leishmania Braziliensis Braziliensis)

Detalhes bibliográficos
Autor(a) principal: Pirmez, Claude
Data de Publicação: 1988
Outros Autores: Marzochi, Mauro A. C., Coutinho, Sergio G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/42975
Resumo: Quatro cães foram inoculados por via intredérmica com 3 x 10**6 promastigotos de Leishmania brasiliensis braziliensis. Três deles desenvolveram lesões no sítio do inóculo, mas uma úlcera mucosa foi detectada 16 meses após o inóculo. Os achados foram similares áqueles verificados na infecção canina natural, bem como na doença humana. Estes resultados sugerem que o cão pode representar um modelo experimental para a infecção causada pela L. b. brasiliensis.
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spelling Pirmez, ClaudeMarzochi, Mauro A. C.Coutinho, Sergio G.2020-08-25T18:27:32Z2020-08-25T18:27:32Z1988PIRMEZ, Claude; MARZOCHI, Mauro C. A.; COUTINHO, Sergio G. Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis). Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 83, n. 1, p. 145-151, abr./jun. 1988.0074-0276https://www.arca.fiocruz.br/handle/icict/4297510.1590/S0074-027619880002000011678-8060Quatro cães foram inoculados por via intredérmica com 3 x 10**6 promastigotos de Leishmania brasiliensis braziliensis. Três deles desenvolveram lesões no sítio do inóculo, mas uma úlcera mucosa foi detectada 16 meses após o inóculo. Os achados foram similares áqueles verificados na infecção canina natural, bem como na doença humana. Estes resultados sugerem que o cão pode representar um modelo experimental para a infecção causada pela L. b. brasiliensis.Four mongrel dogs were intradermically inoculated with 3 x 10**6 Leishmania braziliensis braziliensis promastigotes. Three out of the four animals developed cutaneous lesions respectively 4, 7, and 8 months after. The fourth dog did not develop lesion at the inoculation site, but a mucosal ulcer was seen 16 months after the inoculum. Clinical, histopathological, and serological findings were similar to what is found in natural canine infection as well as in the human disease. These results suggest that dogs may be an useful model for L. b. braziliensis infection.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Imunologia. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Protozoologia. Rio de Janeiro, RJ, Brasil.engFundação Oswaldo Cruz. Instituto Oswaldo Cruz.Mucocutaneous leishmaniasisLeishmania braziliensis braziliensisExperimental canineMucocutaneous leishmaniasisMucocutaneous leishmaniasisExperimental Canine Mucocutaneous Leishmaniasis (Leishmania Braziliensis Braziliensis)info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/42975/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALClaudePirmez_SergioCoutinho_etal_IOC_1988.pdfClaudePirmez_SergioCoutinho_etal_IOC_1988.pdfapplication/pdf398180https://www.arca.fiocruz.br/bitstream/icict/42975/2/ClaudePirmez_SergioCoutinho_etal_IOC_1988.pdf3c94c4bf33babbe2c437b9f4454e9310MD52TEXTClaudePirmez_SergioCoutinho_etal_IOC_1988.pdf.txtClaudePirmez_SergioCoutinho_etal_IOC_1988.pdf.txtExtracted 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dc.title.pt_BR.fl_str_mv Experimental Canine Mucocutaneous Leishmaniasis (Leishmania Braziliensis Braziliensis)
title Experimental Canine Mucocutaneous Leishmaniasis (Leishmania Braziliensis Braziliensis)
spellingShingle Experimental Canine Mucocutaneous Leishmaniasis (Leishmania Braziliensis Braziliensis)
Pirmez, Claude
Mucocutaneous leishmaniasis
Leishmania braziliensis braziliensis
Experimental canine
Mucocutaneous leishmaniasis
Mucocutaneous leishmaniasis
title_short Experimental Canine Mucocutaneous Leishmaniasis (Leishmania Braziliensis Braziliensis)
title_full Experimental Canine Mucocutaneous Leishmaniasis (Leishmania Braziliensis Braziliensis)
title_fullStr Experimental Canine Mucocutaneous Leishmaniasis (Leishmania Braziliensis Braziliensis)
title_full_unstemmed Experimental Canine Mucocutaneous Leishmaniasis (Leishmania Braziliensis Braziliensis)
title_sort Experimental Canine Mucocutaneous Leishmaniasis (Leishmania Braziliensis Braziliensis)
author Pirmez, Claude
author_facet Pirmez, Claude
Marzochi, Mauro A. C.
Coutinho, Sergio G.
author_role author
author2 Marzochi, Mauro A. C.
Coutinho, Sergio G.
author2_role author
author
dc.contributor.author.fl_str_mv Pirmez, Claude
Marzochi, Mauro A. C.
Coutinho, Sergio G.
dc.subject.other.pt_BR.fl_str_mv Mucocutaneous leishmaniasis
Leishmania braziliensis braziliensis
topic Mucocutaneous leishmaniasis
Leishmania braziliensis braziliensis
Experimental canine
Mucocutaneous leishmaniasis
Mucocutaneous leishmaniasis
dc.subject.en.pt_BR.fl_str_mv Experimental canine
Mucocutaneous leishmaniasis
Mucocutaneous leishmaniasis
description Quatro cães foram inoculados por via intredérmica com 3 x 10**6 promastigotos de Leishmania brasiliensis braziliensis. Três deles desenvolveram lesões no sítio do inóculo, mas uma úlcera mucosa foi detectada 16 meses após o inóculo. Os achados foram similares áqueles verificados na infecção canina natural, bem como na doença humana. Estes resultados sugerem que o cão pode representar um modelo experimental para a infecção causada pela L. b. brasiliensis.
publishDate 1988
dc.date.issued.fl_str_mv 1988
dc.date.accessioned.fl_str_mv 2020-08-25T18:27:32Z
dc.date.available.fl_str_mv 2020-08-25T18:27:32Z
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dc.identifier.citation.fl_str_mv PIRMEZ, Claude; MARZOCHI, Mauro C. A.; COUTINHO, Sergio G. Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis). Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 83, n. 1, p. 145-151, abr./jun. 1988.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/42975
dc.identifier.issn.pt_BR.fl_str_mv 0074-0276
dc.identifier.doi.none.fl_str_mv 10.1590/S0074-02761988000200001
dc.identifier.eissn.none.fl_str_mv 1678-8060
identifier_str_mv PIRMEZ, Claude; MARZOCHI, Mauro C. A.; COUTINHO, Sergio G. Experimental canine mucocutaneous leishmaniasis (Leishmania braziliensis braziliensis). Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 83, n. 1, p. 145-151, abr./jun. 1988.
0074-0276
10.1590/S0074-02761988000200001
1678-8060
url https://www.arca.fiocruz.br/handle/icict/42975
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dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto Oswaldo Cruz.
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