Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa

Detalhes bibliográficos
Autor(a) principal: Silva, Orivaldo Benedito da
Data de Publicação: 2022
Outros Autores: Destacio, Jéssica Chaves, Paula, Glescieli Rodrigues, Rodrigues, Fabiana Aparecida Caldart, Rieder, Arno
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/55250
Resumo: Universidade do Estado de Mato Grosso Carlos Alberto Reyes Maldonado. Faculdade de Ciências Biológicas e Agrárias. Cáceres, MT, Brasil.
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spelling Silva, Orivaldo Benedito daDestacio, Jéssica ChavesPaula, Glescieli RodriguesRodrigues, Fabiana Aparecida CaldartRieder, Arno2022-10-23T21:22:09Z2022-10-23T21:22:09Z2022SILVA, Orivaldo Benedito da et al. Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa. Revista Fitos, v. 16, n. 3, p. 305-314, Sept. 2022.1808-9569https://www.arca.fiocruz.br/handle/icict/5525010.32712/2446-4775.2022.13122446-4775engFundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Centro de Inovação em Biodiversidade e SaúdeEffects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleUniversidade do Estado de Mato Grosso Carlos Alberto Reyes Maldonado. Faculdade de Ciências Biológicas e Agrárias. Cáceres, MT, Brasil.Universidade do Estado de Mato Grosso Carlos Alberto Reyes Maldonado. Faculdade de Ciências Biológicas e Agrárias. Cáceres, MT, Brasil.Universidade do Estado de Mato Grosso Carlos Alberto Reyes Maldonado. Faculdade de Ciências Biológicas e Agrárias. Cáceres, MT, Brasil.Universidade do Estado de Mato Grosso Carlos Alberto Reyes Maldonado. Faculdade de Ciências Biológicas e Agrárias. Cáceres, MT, Brasil.Universidade do Estado de Mato Grosso Carlos Alberto Reyes Maldonado. Faculdade de Ciências Exatas e Tecnológicas. Cáceres, MT, Brasil / Universidade do Estado de Mato Grosso Carlos Alberto Reyes Maldonado. Faculdade de Ciências Biológicas e Agrárias. Cáceres, MT, Brasil.This study assessed the cytotoxic and genotoxic potentials of extracts of Psittacanthus acinarius (Mart.) Mart. and Psittacanthus cordatus (Hoffmanns.) in the root cell cycle of Allium cepa L. Aqueous leaf extracts of P. acinarius and P. cordatus at three concentrations: 0.00, 5 and 20 mg/mL for 24 hours. Histological slides were prepared and mitotic indices (MI %) and chromosomal alteration indices (CAI %) were determined. Inhibitory effects of the aqueous extract of leaves of P. acinarius were observed in 46.33 and 46.00% at concentrations of 5 and 20 mg/mL, respectively, in relation to the control (62.83%), in addition to a higher chromosomal alteration index by 0.26% at a concentration of 20 mg/mL. In the aqueous extract of leaves of P. cordatus, the greatest inhibitory effects were 33.83 and 35.50% in the concentrations of 5 and 20 mg/mL, respectively, in relation to the control (88.16%) and the highest alteration index chromosomal (3.30%) at 5 mg/mL. The aqueous leaf extracts of P. acinarius and P. cordatus at concentration of 5 and 20 mg/mL inhibit MI %, reveal an irregular recovery or prevent it, and induce chromosomal alterations, suggesting cytotoxic and genotoxic effects on division of meristematic cells of A. cepa.Chromosomal alterationMedicinal mistletoeMitotic indexBioassaysinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/55250/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALo_b_d_et_all.pdfapplication/pdf565014https://www.arca.fiocruz.br/bitstream/icict/55250/2/o_b_d_et_all.pdf4119ddfafbaace92524e78617acd7722MD52icict/552502022-12-12 10:58:22.223oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-12-12T13:58:22Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa
title Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa
spellingShingle Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa
Silva, Orivaldo Benedito da
Chromosomal alteration
Medicinal mistletoe
Mitotic index
Bioassays
title_short Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa
title_full Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa
title_fullStr Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa
title_full_unstemmed Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa
title_sort Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa
author Silva, Orivaldo Benedito da
author_facet Silva, Orivaldo Benedito da
Destacio, Jéssica Chaves
Paula, Glescieli Rodrigues
Rodrigues, Fabiana Aparecida Caldart
Rieder, Arno
author_role author
author2 Destacio, Jéssica Chaves
Paula, Glescieli Rodrigues
Rodrigues, Fabiana Aparecida Caldart
Rieder, Arno
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Silva, Orivaldo Benedito da
Destacio, Jéssica Chaves
Paula, Glescieli Rodrigues
Rodrigues, Fabiana Aparecida Caldart
Rieder, Arno
dc.subject.en.en_US.fl_str_mv Chromosomal alteration
Medicinal mistletoe
Mitotic index
Bioassays
topic Chromosomal alteration
Medicinal mistletoe
Mitotic index
Bioassays
description Universidade do Estado de Mato Grosso Carlos Alberto Reyes Maldonado. Faculdade de Ciências Biológicas e Agrárias. Cáceres, MT, Brasil.
publishDate 2022
dc.date.accessioned.fl_str_mv 2022-10-23T21:22:09Z
dc.date.available.fl_str_mv 2022-10-23T21:22:09Z
dc.date.issued.fl_str_mv 2022
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv SILVA, Orivaldo Benedito da et al. Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa. Revista Fitos, v. 16, n. 3, p. 305-314, Sept. 2022.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/55250
dc.identifier.issn.none.fl_str_mv 1808-9569
dc.identifier.doi.none.fl_str_mv 10.32712/2446-4775.2022.1312
dc.identifier.eissn.none.fl_str_mv 2446-4775
identifier_str_mv SILVA, Orivaldo Benedito da et al. Effects cytotoxic and genotoxic of Psittacanthus acinarius and Psittacanthus cordatus (mistletoe) on Allium cepa. Revista Fitos, v. 16, n. 3, p. 305-314, Sept. 2022.
1808-9569
10.32712/2446-4775.2022.1312
2446-4775
url https://www.arca.fiocruz.br/handle/icict/55250
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Centro de Inovação em Biodiversidade e Saúde
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Centro de Inovação em Biodiversidade e Saúde
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
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institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/55250/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/55250/2/o_b_d_et_all.pdf
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