ADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection

Detalhes bibliográficos
Autor(a) principal: Yu, Wen-Han
Data de Publicação: 2018
Outros Autores: Cosgrove, Cormac, Berger, Christoph T., Cheney, Patrick C., Krykbaeva, Marina, Kim, Arthur Y., Lewis-Ximenez, Lia, Lauer, Georg M., Alter, Galit
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/31759
Resumo: The Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts. USA / Massachusetts Institute of Technology. Department of Biological Engineering. Cambridge, Massachussets, USA.
id CRUZ_febec054dae57b833d3244f6f586529c
oai_identifier_str oai:www.arca.fiocruz.br:icict/31759
network_acronym_str CRUZ
network_name_str Repositório Institucional da FIOCRUZ (ARCA)
repository_id_str 2135
spelling Yu, Wen-HanCosgrove, CormacBerger, Christoph T.Cheney, Patrick C.Krykbaeva, MarinaKim, Arthur Y.Lewis-Ximenez, LiaLauer, Georg M.Alter, Galit2019-02-19T15:46:01Z2019-02-19T15:46:01Z2018YOU, Wen-Han et al. ADCC-Mediated CD56DIM NK Cell Responses are Associated with early HBsAg Clearence in Acute HBV Infection. Pathogens and Immunity, v. 3, n. 1, p.1-2, Feb. 2018.2469-2964https://www.arca.fiocruz.br/handle/icict/3175910.20411/pai.v3i1.228engCase Western Reserve UniversityCélulas NKVírus da Hepatite BHBVNK cellsHBsAgADCCCitotoxicidade Celular Dependente de AnticorposAntígenos de Superfície da Hepatite BADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infectioninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleThe Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts. USA / Massachusetts Institute of Technology. Department of Biological Engineering. Cambridge, Massachussets, USA.The Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts. USA.University Hospital Basel. Dept. of Biomedicine. Basel, Switzerland.The Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts. USA.The Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts. USA.Massachusetts General Hospital, Boston, Massachusetts, USA.Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ. Brasil.Massachusetts General Hospital, Boston, Massachusetts, USA.The Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts. USA.Hepatitis B virus (HBV) affects up to 400 million people worldwide and accounts for approximately one million deaths per year from liver pathologies. Current treatment regimens are effective in suppressing viremia but usually have to be taken indefinitely, warranting research into new therapeutic approaches. Acute HBV infection in adults almost universally results in resolution of viremia, with the exception of immunocompromised persons, suggesting that the immune response can functionally cure or even eradicate HBV infection.info:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txtlicense.txttext/plain; charset=utf-82991https://www.arca.fiocruz.br/bitstream/icict/31759/1/license.txt5a560609d32a3863062d77ff32785d58MD51ORIGINALlialewis_ximenez_etal_IOC_2018.pdflialewis_ximenez_etal_IOC_2018.pdfapplication/pdf767639https://www.arca.fiocruz.br/bitstream/icict/31759/2/lialewis_ximenez_etal_IOC_2018.pdfe6d90d444f7a68d2c87e8e8c6b2e176bMD52TEXTlialewis_ximenez_etal_IOC_2018.pdf.txtlialewis_ximenez_etal_IOC_2018.pdf.txtExtracted texttext/plain46726https://www.arca.fiocruz.br/bitstream/icict/31759/3/lialewis_ximenez_etal_IOC_2018.pdf.txt4d4965796e7a2fbe09b7df28e84842e1MD53icict/317592019-02-22 23:44:01.269oai:www.arca.fiocruz.br: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ório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352019-02-23T02:44:01Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.pt_BR.fl_str_mv ADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection
title ADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection
spellingShingle ADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection
Yu, Wen-Han
Células NK
Vírus da Hepatite B
HBV
NK cells
HBsAg
ADCC
Citotoxicidade Celular Dependente de Anticorpos
Antígenos de Superfície da Hepatite B
title_short ADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection
title_full ADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection
title_fullStr ADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection
title_full_unstemmed ADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection
title_sort ADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection
author Yu, Wen-Han
author_facet Yu, Wen-Han
Cosgrove, Cormac
Berger, Christoph T.
Cheney, Patrick C.
Krykbaeva, Marina
Kim, Arthur Y.
Lewis-Ximenez, Lia
Lauer, Georg M.
Alter, Galit
author_role author
author2 Cosgrove, Cormac
Berger, Christoph T.
Cheney, Patrick C.
Krykbaeva, Marina
Kim, Arthur Y.
Lewis-Ximenez, Lia
Lauer, Georg M.
Alter, Galit
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Yu, Wen-Han
Cosgrove, Cormac
Berger, Christoph T.
Cheney, Patrick C.
Krykbaeva, Marina
Kim, Arthur Y.
Lewis-Ximenez, Lia
Lauer, Georg M.
Alter, Galit
dc.subject.other.pt_BR.fl_str_mv Células NK
Vírus da Hepatite B
topic Células NK
Vírus da Hepatite B
HBV
NK cells
HBsAg
ADCC
Citotoxicidade Celular Dependente de Anticorpos
Antígenos de Superfície da Hepatite B
dc.subject.en.pt_BR.fl_str_mv HBV
NK cells
HBsAg
ADCC
dc.subject.decs.pt_BR.fl_str_mv Citotoxicidade Celular Dependente de Anticorpos
Antígenos de Superfície da Hepatite B
description The Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts. USA / Massachusetts Institute of Technology. Department of Biological Engineering. Cambridge, Massachussets, USA.
publishDate 2018
dc.date.issued.fl_str_mv 2018
dc.date.accessioned.fl_str_mv 2019-02-19T15:46:01Z
dc.date.available.fl_str_mv 2019-02-19T15:46:01Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv YOU, Wen-Han et al. ADCC-Mediated CD56DIM NK Cell Responses are Associated with early HBsAg Clearence in Acute HBV Infection. Pathogens and Immunity, v. 3, n. 1, p.1-2, Feb. 2018.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/31759
dc.identifier.issn.pt_BR.fl_str_mv 2469-2964
dc.identifier.doi.none.fl_str_mv 10.20411/pai.v3i1.228
identifier_str_mv YOU, Wen-Han et al. ADCC-Mediated CD56DIM NK Cell Responses are Associated with early HBsAg Clearence in Acute HBV Infection. Pathogens and Immunity, v. 3, n. 1, p.1-2, Feb. 2018.
2469-2964
10.20411/pai.v3i1.228
url https://www.arca.fiocruz.br/handle/icict/31759
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Case Western Reserve University
publisher.none.fl_str_mv Case Western Reserve University
dc.source.none.fl_str_mv reponame:Repositório Institucional da FIOCRUZ (ARCA)
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Repositório Institucional da FIOCRUZ (ARCA)
collection Repositório Institucional da FIOCRUZ (ARCA)
bitstream.url.fl_str_mv https://www.arca.fiocruz.br/bitstream/icict/31759/1/license.txt
https://www.arca.fiocruz.br/bitstream/icict/31759/2/lialewis_ximenez_etal_IOC_2018.pdf
https://www.arca.fiocruz.br/bitstream/icict/31759/3/lialewis_ximenez_etal_IOC_2018.pdf.txt
bitstream.checksum.fl_str_mv 5a560609d32a3863062d77ff32785d58
e6d90d444f7a68d2c87e8e8c6b2e176b
4d4965796e7a2fbe09b7df28e84842e1
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
repository.name.fl_str_mv Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv repositorio.arca@fiocruz.br
_version_ 1813009111832330240

Registros relacionados