In vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extract

Detalhes bibliográficos
Autor(a) principal: Victorio, Cristiane Pimentel
Data de Publicação: 2021
Outros Autores: Silva, Davi Oliveira e, Alviano, Daniela Sales, Alviano, Celuta Sales, Kuster, Ricardo Machado, Lage, Celso Luiz Salgueiro
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da FIOCRUZ (ARCA)
Texto Completo: https://www.arca.fiocruz.br/handle/icict/48193
Resumo: Fundação Centro Universitário da Zona Oeste do Rio de Janeiro. Centro Setorial de Ciências Biológicas e da Saúde. Rio de Janeiro, RJ, Brasil.
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spelling Victorio, Cristiane PimentelSilva, Davi Oliveira eAlviano, Daniela SalesAlviano, Celuta SalesKuster, Ricardo MachadoLage, Celso Luiz Salgueiro2021-07-12T20:24:17Z2021-07-12T20:24:17Z2021VICTORIO, Cristiane Pimentel et al. In vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extract. Revista Fitos, v. 15, n. 2, p. 136-143, June 2021.1808-9569https://www.arca.fiocruz.br/handle/icict/4819310.32712/2446-4775.2021.10372446-4775engFundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Centro de Inovação em Biodiversidade e SaúdeIn vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extractAtividade antimicrobiana in vitro das frações apolares dos extratos de folhas de Alpinia zerumbet e A. purpuratainfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleFundação Centro Universitário da Zona Oeste do Rio de Janeiro. Centro Setorial de Ciências Biológicas e da Saúde. Rio de Janeiro, RJ, Brasil.Universidade Federal de Ouro Preto. Instituto de Ciências Exatas e Biológicas. Departamento de Biodiversidade, Evolução e Meio Ambiente. Ouro Preto, MG, Brasil.Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Instituto de Microbiologia Paulo de Góes. Rio de Janeiro, RJ, Brasil.Universidade Federal do Rio de Janeiro. Centro de Ciências da Saúde. Instituto de Microbiologia Paulo de Góes. Rio de Janeiro, RJ, Brasil.Universidade Federal do Espírito Santo. Departamento de Química. Vitória, ES, Brasil.Instituto Nacional da Propriedade Industrial. Rio de Janeiro, RJ, Brasil.This study aimed to evaluate the in vitro antimicrobial activity of fractions of leaf hydroalcoholic crude extracts: hexane, dichloromethane, ethyl acetate and butanolic of Alpinia zerumbet and A. purpurata by the agar drop diffusion method in order to screen the main compounds involved in antimicrobial activity. Leaves of A. zerumbet (Pers.) B.L. Burtt et R.M. Sm. and A. purpurata (Vieill) K. Schum adult plants were collected and then dried and macerated in 70% ethanol. Leaf extracts were further partitioned using solvents in increasing polarity. Dichloromethane fractions were analyzed by gas chromatography/mass spectrometry (GC/MS). The major compound in the dichloromethane fraction of both species was the hexadecanoic acid (palmitic acid). By drop diffusion assay, the antimicrobial activity of crude extract, as well as fractions of hexane, dichloromethane, ethyl acetate and butanolic, was evaluated against pathogenic bacteria and fungi. No bacteria were inhibited. However, the dichloromethane fraction exhibited promising antifungal activity against the following fungi tested: Cryptococcus neoformans, Fonsecaea pedrosoi, Trichophytoon rubrum, Microsporium canis and M. gypseum.Antifungal activityZingiberaceaeAgar drop diffusionFilamentous fungiYeastinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da FIOCRUZ (ARCA)instname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZLICENSElicense.txttext/plain1748https://www.arca.fiocruz.br/bitstream/icict/48193/1/license.txt8a4605be74aa9ea9d79846c1fba20a33MD51ORIGINALc_p_et_all.pdfArtigo em Inglêsapplication/pdf317611https://www.arca.fiocruz.br/bitstream/icict/48193/2/c_p_et_all.pdf53df03ceffca19781e8aca0f16c111faMD521037-Multimedia-7212-1-17-20210623.mp31037-Multimedia-7212-1-17-20210623.mp3Áudio em Inglês - Título, autoria e resumoaudio/basic644492https://www.arca.fiocruz.br/bitstream/icict/48193/4/1037-Multimedia-7212-1-17-20210623.mp3c2c1cd1a0606be50752d7095c8014a7aMD54TEXTc_p_et_all.pdf.txtc_p_et_all.pdf.txtExtracted texttext/plain28471https://www.arca.fiocruz.br/bitstream/icict/48193/3/c_p_et_all.pdf.txt03cb3e1a9bbcf867d2174033955fe823MD53icict/481932022-12-08 13:36:12.258oai:www.arca.fiocruz.br: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Repositório InstitucionalPUBhttps://www.arca.fiocruz.br/oai/requestrepositorio.arca@fiocruz.bropendoar:21352022-12-08T16:36:12Repositório Institucional da FIOCRUZ (ARCA) - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.en_US.fl_str_mv In vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extract
dc.title.alternative.pt_BR.fl_str_mv Atividade antimicrobiana in vitro das frações apolares dos extratos de folhas de Alpinia zerumbet e A. purpurata
title In vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extract
spellingShingle In vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extract
Victorio, Cristiane Pimentel
Antifungal activity
Zingiberaceae
Agar drop diffusion
Filamentous fungi
Yeast
title_short In vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extract
title_full In vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extract
title_fullStr In vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extract
title_full_unstemmed In vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extract
title_sort In vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extract
author Victorio, Cristiane Pimentel
author_facet Victorio, Cristiane Pimentel
Silva, Davi Oliveira e
Alviano, Daniela Sales
Alviano, Celuta Sales
Kuster, Ricardo Machado
Lage, Celso Luiz Salgueiro
author_role author
author2 Silva, Davi Oliveira e
Alviano, Daniela Sales
Alviano, Celuta Sales
Kuster, Ricardo Machado
Lage, Celso Luiz Salgueiro
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Victorio, Cristiane Pimentel
Silva, Davi Oliveira e
Alviano, Daniela Sales
Alviano, Celuta Sales
Kuster, Ricardo Machado
Lage, Celso Luiz Salgueiro
dc.subject.en.en_US.fl_str_mv Antifungal activity
Zingiberaceae
Agar drop diffusion
Filamentous fungi
Yeast
topic Antifungal activity
Zingiberaceae
Agar drop diffusion
Filamentous fungi
Yeast
description Fundação Centro Universitário da Zona Oeste do Rio de Janeiro. Centro Setorial de Ciências Biológicas e da Saúde. Rio de Janeiro, RJ, Brasil.
publishDate 2021
dc.date.accessioned.fl_str_mv 2021-07-12T20:24:17Z
dc.date.available.fl_str_mv 2021-07-12T20:24:17Z
dc.date.issued.fl_str_mv 2021
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.citation.fl_str_mv VICTORIO, Cristiane Pimentel et al. In vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extract. Revista Fitos, v. 15, n. 2, p. 136-143, June 2021.
dc.identifier.uri.fl_str_mv https://www.arca.fiocruz.br/handle/icict/48193
dc.identifier.issn.none.fl_str_mv 1808-9569
dc.identifier.doi.none.fl_str_mv 10.32712/2446-4775.2021.1037
dc.identifier.eissn.none.fl_str_mv 2446-4775
identifier_str_mv VICTORIO, Cristiane Pimentel et al. In vitro antimicrobial activity of Alpinia zerumbet and A. purpurata nonpolar fraction of leaf extract. Revista Fitos, v. 15, n. 2, p. 136-143, June 2021.
1808-9569
10.32712/2446-4775.2021.1037
2446-4775
url https://www.arca.fiocruz.br/handle/icict/48193
dc.language.iso.fl_str_mv eng
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Centro de Inovação em Biodiversidade e Saúde
publisher.none.fl_str_mv Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Centro de Inovação em Biodiversidade e Saúde
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