Estimulação medular epidural para o tratamento da dor crônica: uma revisão de literatura
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Tipo de documento: | Trabalho de conclusão de curso |
Idioma: | por |
Título da fonte: | Repositório do Centro Universitário Braz Cubas |
Texto Completo: | https://repositorio.cruzeirodosul.edu.br/handle/123456789/1453 |
Resumo: | Introduction: According to the International Association for the Study of Pain, pain is defined as a sensitive and unpleasant experience associated with actual or potential tissue damage. According to the temporal parameters, it can be classified as acute when it exerts a defensive alert tone against an injury, and lasts less than three months; and chronic when it lasts more than three months, not exercising a biological protective role. Conservative treatment can be based on drug therapies with the use of drugs, non-invasive anesthetic techniques, physical therapy and psychotherapy. Spinal cord stimulation is a neuromodulation technique that involves surgical or percutaneous implantation of electrodes in the epidural space, in the region of the dorsal horn of the spinal cord. It consists of replacing the sensation of pain by paresthesia, through the electric current. Objectives: To describe spinal cord stimulation in the management of chronic pain; explain the functional mechanism of spinal cord stimulation, describing the technical parameters of stimulation, report how the implantation stages of the electrodes, elucidate the main indications, list the main reconstructed complications. Materials and Methods: Exploratory, descriptive, literature review type study. Data collection was carried out from August 2019 to October 2020. Results: In view of the legacy of satisfactory results, EME is a widespread technique for the treatment of painful pathologies refractory to therapies against, including the unsuccessful spinal surgery, complex regional painful syndrome, peripheral vascular disease and intractable angina. Pain scales are used to measure pain magnitude and proportion to the definition of effective therapeutic parameters. As complications are infrequent, however, occurrences of a technical or biological nature may occur. Conclusion: Neuromodulation techniques, therefore, assist in developing to adapt to the reality of patients, with modern software and judicious materials. Therefore, spinal cord stimulation is effective and safe for the treatment of chronic refractory to conventional therapy. |
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Estimulação medular epidural para o tratamento da dor crônica: uma revisão de literaturaDor crônicaNeuromodulaçãoMedula espinhalCNPQ::CIENCIAS DA SAUDE::MEDICINAIntroduction: According to the International Association for the Study of Pain, pain is defined as a sensitive and unpleasant experience associated with actual or potential tissue damage. According to the temporal parameters, it can be classified as acute when it exerts a defensive alert tone against an injury, and lasts less than three months; and chronic when it lasts more than three months, not exercising a biological protective role. Conservative treatment can be based on drug therapies with the use of drugs, non-invasive anesthetic techniques, physical therapy and psychotherapy. Spinal cord stimulation is a neuromodulation technique that involves surgical or percutaneous implantation of electrodes in the epidural space, in the region of the dorsal horn of the spinal cord. It consists of replacing the sensation of pain by paresthesia, through the electric current. Objectives: To describe spinal cord stimulation in the management of chronic pain; explain the functional mechanism of spinal cord stimulation, describing the technical parameters of stimulation, report how the implantation stages of the electrodes, elucidate the main indications, list the main reconstructed complications. Materials and Methods: Exploratory, descriptive, literature review type study. Data collection was carried out from August 2019 to October 2020. Results: In view of the legacy of satisfactory results, EME is a widespread technique for the treatment of painful pathologies refractory to therapies against, including the unsuccessful spinal surgery, complex regional painful syndrome, peripheral vascular disease and intractable angina. Pain scales are used to measure pain magnitude and proportion to the definition of effective therapeutic parameters. As complications are infrequent, however, occurrences of a technical or biological nature may occur. Conclusion: Neuromodulation techniques, therefore, assist in developing to adapt to the reality of patients, with modern software and judicious materials. Therefore, spinal cord stimulation is effective and safe for the treatment of chronic refractory to conventional therapy.Introdução: Segundo a Associação Internacional para o Estudo da Dor, a dor é definida como uma experiência sensitiva e emocional desagradável associada a um dano tecidual real ou potencial. De acordo com os parâmetros temporais, pode-se classificá-la como aguda quando exerce uma finalidade de alerta defensivo ante uma lesão, e dura menos de três meses; e crônica quando dura mais de três meses, não exercendo papel biológico de proteção. O tratamento conservador pode ser baseado em terapias medicamentosas com o uso de fármacos, técnicas anestésicas nãoinvasivas, fisioterapia e psicoterapia. A estimulação medular epidural é uma técnica de neuromodulação que envolve a implantação cirúrgica ou percutânea de eletrodos no espaço epidural, na região do corno dorsal da medula. Ela consiste em substituir a sensação de dor por parestesia, através da corrente elétrica. Objetivos: Descrever a estimulação medular epidural no manejo da dor crônica; explanar o mecanismo funcional da estimulação medular epidural, descrever os parâmetros técnicos de estimulação, relatar as etapas de implantação dos eletrodos, elucidar as principais indicações cirúrgicas, elencar as principais complicações cirúrgicas. Materiais e Métodos: Estudo exploratório, descritivo, do tipo revisão de literatura, cuja coleta de dados foi efetuada no período de agosto de 2019 a outubro de 2020. Resultados: Em face ao legado de resultados satisfatórios, a EME é uma técnica amplamente difundida para o tratamento de patologias dolorosas refratárias a terapias convencionais, dentre elas a síndrome do insucesso da cirurgia espinhal, síndrome dolorosa regional complexa, doença vascular periférica e angina intratável. As escalas de dor são utilizadas para mensurar a magnitude álgica e propor a definição de parâmetros terapêuticos eficazes. As complicações são infrequentes, entretanto, podem ocorrer falhas de natureza técnica ou biológica. Conclusão: As técnicas de neuromodulação, portanto, vêm se desenvolvendo para se adaptar à realidade dos pacientes, com softwares modernos e materiais criteriosos. Logo, a estimulação medular epidural é eficaz e segura para o tratamento dor crônica refratária a terapia convencional.Centro Universitário de João PessoaBrasilUNIPÊAndrade, Emerson Magno Fernandes dehttp://lattes.cnpq.br/8755121434441999Fernandes, Matheus Pereira2021-02-03T17:54:26Z2021-02-032021-02-03T17:54:26Z2020-12-10info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisapplication/pdfhttps://repositorio.cruzeirodosul.edu.br/handle/123456789/1453porASHMAWI, H. A.; FREIRE, G. M. G. Peripheral and central sensitization. Revista Dor, [S. l.], v. 17, n. Suppl 1, p. 31–34, 2016. Disponível em: https://doi.org/10.5935/1806-0013.20160044 BASBAUM, A. I.; JESSEL, T. M. Dor. In: KANDEL, E. R. et al. (org.). Princípios de Neurociências. 5. ed. Porto Alegre: AMGH, 2014. p. 462–482. E-book. BENDERSKY, D.; YAMPOLSKY, C. Is Spinal Cord Stimulation Safe? A Review of Its Complications. World Neurosurgery, [S. l.], v. 82, n. 6, p. 1359–1368, 2014. Disponível em: https://doi.org/10.1016/j.wneu.2013.06.012 BREIVIK, H. et al. Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment. European Journal of Pain, [S. l.], v. 10, n. 4, p. 287–287, 2006. Disponível em: https://doi.org/10.1016/j.ejpain.2005.06.009 BURCKHARDT, C. S.; ANDERSON, K. L. The Quality of Life Scale (QOLS): reliability, validity, and utilization. Health and quality of life outcomes, [S. l.], v. 1, p. 60, 2003. Disponível em: https://doi.org/10.1186/1477-7525-1-60 CAMERON, T. Safety and efficacy of spinal cord stimulation for the treatment of chronic pain: a 20-year literature review. Journal of Neurosurgery: Spine, [S. l.], v. 100, n. 3, p. 254–267, 2004. Disponível em: https://doi.org/10.3171/spi.2004.100.3.0254 CAMPOS, W. K. et al. Determinants for Meaningful Clinical Improvement of Pain and Health‐Related Quality of Life After Spinal Cord Stimulation for Chronic Intractable Pain. Neuromodulation: Technology at the Neural Interface, [S. l.], v. 22, n. 3, p. 280–289, 2019. Disponível em: https://doi.org/10.1111/ner.12891 CHAKRAVARTHY, K. et al. Spinal Cord Stimulation for Treating Chronic Pain: Reviewing Preclinical and Clinical Data on Paresthesia-Free High-Frequency Therapy. Neuromodulation, [S. l.], v. 21, n. 1, p. 10–18, 2018. Disponível em: https://doi.org/10.1111/ner.12721 CONGER, A. et al. The Effectiveness of Spinal Cord Stimulation for the Treatment of Axial Low Back Pain: A Systematic Review with Narrative Synthesis. Pain Medicine, [S. l.], v. 0, n. 0, p. 1–14, 2020. Disponível em: https://doi.org/10.1093/pm/pnaa142 CUI, J. et al. Spinal cord stimulation attenuates augmented dorsal horn release of excitatory amino acids in mononeuropathy via a GABAergic mechanism. PAIN, [S. l.], v. 73, n. 1, p. 87–95, 1997. Disponível em: https://doi.org/10.1016/S0304- 3959(97)00077-8 DE RIDDER, D.; VANNESTE, S. Burst and Tonic Spinal Cord Stimulation: Different and Common Brain Mechanisms. Neuromodulation: Technology at the Neural Interface, [S. l.], v. 19, n. 1, p. 47–59, 2016. Disponível em: https://doi.org/10.1111/ner.12368 DEER, T. R. et al. The Appropriate Use of Neurostimulation: Avoidance and Treatment of Complications of Neurostimulation Therapies for the Treatment of Chronic Pain. Neuromodulation: Technology at the Neural Interface, [S. l.], v. 17, n. 6, p. 571–598, 2014. Disponível em: https://doi.org/10.1111/ner.12206 DUPRÉ, D. A. et al. Spinal Cord Stimulator Explantation: Motives for Removal of Surgically Placed Paddle Systems. Pain practice : the official journal of World Institute of Pain, [S. l.], v. 18, n. 4, p. 500–504, 2018. Disponível em: https://doi.org/10.1111/papr.12639 ELDABE, S.; BUCHSER, E.; DUARTE, R. V. Complications of Spinal Cord Stimulation and Peripheral Nerve Stimulation Techniques: A Review of the Literature. Pain Medicine, [S. l.], v. 17, n. 2, p. pnv025, 2015. Disponível em: https://doi.org/10.1093/pm/pnv025 FALAVIGNA, A. et al. Instrumentos de avaliação clínica e funcional em cirurgia da coluna vertebral. Coluna/Columna, [S. l.], v. 10, n. 1, p. 62–67, 2011. Disponível em: https://doi.org/10.1590/S1808-18512011000100012 FALOWSKI, S. M. et al. Spinal Cord Stimulation Infection Rate and Risk Factors: Results From a United States Payer Database. Neuromodulation: Technology at the Neural Interface, [S. l.], v. 22, n. 2, p. 179–189, 2019. Disponível em: https://doi.org/10.1111/ner.12843 FENTON, B. W.; SHIH, E.; ZOLTON, J. The neurobiology of pain perception in normal and persistent pain. Pain Management, [S. l.], v. 5, n. 4, p. 297–317, 2015. Disponível em: https://doi.org/10.2217/pmt.15.27 GIL, A. C. Métodos e Técinas de Pesquisa Social. 6. ed. São Paulo: Atlas, 2008. E-book. GUREJE, O. et al. Persistent Pain and Well-being. JAMA, [S. l.], v. 280, n. 2, p. 147, 1998. Disponível em: https://doi.org/10.1001/jama.280.2.147 HAUTVAST, R. W. M. et al. Spinal cord stimulation in chronic intractable angina pectoris: A randomized, controlled efficacy study. American Heart Journal, [S. l.], v. 136, n. 6, p. 1114–1120, 1998. Disponível em: https://doi.org/10.1016/S0002- 8703(98)70171-1 HEAD, J. et al. Waves of Pain Relief: A Systematic Review of Clinical Trials in Spinal Cord Stimulation Waveforms for the Treatment of Chronic Neuropathic Low Back and Leg Pain. World neurosurgery, [S. l.], v. 131, p. 264- 274.e3, 2019. Disponível em: https://doi.org/10.1016/j.wneu.2019.07.167 JAMES, S. L. et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. The Lancet, [S. l.], v. 392, n. 10159, p. 1789–1858, 2018. Disponível em: https://doi.org/10.1016/S0140-6736(18)32279-7 JIVEGÅRD, L. E. H. et al. Effects of spinal cord stimulation (SCS) in patients with inoperable severe lower limb ischaemia: A prospective randomised controlled study. European Journal of Vascular and Endovascular Surgery, [S. l.], v. 9, n. 4, p. 421–425, 1995. Disponível em: https://doi.org/10.1016/S1078-5884(05)80010-3 KAPURAL, L. et al. Novel 10-kHz High-frequency Therapy (HF10 Therapy) Is Superior to Traditional Low-frequency Spinal Cord Stimulation for the Treatment of Chronic Back and Leg Pain. Anesthesiology, [S. l.], v. 123, n. 4, p. 851–860, 2015. Disponível em: https://doi.org/10.1097/ALN.0000000000000774 KEMLER, M. A. et al. Spinal Cord Stimulation in Patients with Chronic Reflex Sympathetic Dystrophy. New England Journal of Medicine, [S. l.], v. 343, n. 9, p. 618–624, 2000. Disponível em: https://doi.org/10.1056/NEJM200008313430904 KEMLER, M. A. et al. The effect of spinal cord stimulation in patients with chronic reflex sympathetic dystrophy: Two years’ follow-up of the randomized controlled trial. Annals of Neurology, [S. l.], v. 55, n. 1, p. 13–18, 2004. Disponível em: https://doi.org/10.1002/ana.10996 KEMLER, M. A. et al. Effect of spinal cord stimulation for chronic complex regional pain syndrome Type I: five-year final follow-up of patients in a randomized controlled trial. Journal of Neurosurgery, [S. l.], v. 108, n. 2, p. 292–298, 2008. Disponível em: https://doi.org/10.3171/JNS/2008/108/2/0292 KUMAR, K. et al. Spinal cord stimulation versus conventional medical management for neuropathic pain: A multicentre randomised controlled trial in patients with failed back surgery syndrome. PAIN, [S. l.], v. 132, n. 1, p. 179–188, 2007. Disponível em: https://doi.org/10.1016/j.pain.2007.07.028 KUMAR, K. et al. 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Disponível em: https://doi.org/10.1126/science.150.3699.971 NORTH, R. B. et al. Spinal cord stimulation for axial low back pain: a prospective, controlled trial comparing dual with single percutaneous electrodes. Spine, [S. l.], v. 30, n. 12, p. 1412–8, 2005. Disponível em: https://doi.org/10.1097/01.brs.0000166502.05449.a8 NORTH, R. B.; GUARINO, A. H. Spinal Cord Stimulation for Failed Back Surgery Syndrome: Technical Advances, Patient Selection and Outcome. Neuromodulation: Technology at the Neural Interface, [S. l.], v. 2, n. 3, p. 171–178, 1999. Disponível em: https://doi.org/10.1046/j.1525-1403.1999.00171.x PAN, X. et al. Spinal Cord Stimulation for Refractory Angina Pectoris: A Systematic Review and Meta-analysis. The Clinical journal of pain, [S. l.], v. 33, n. 6, p. 543– 551, 2017. Disponível em: https://doi.org/10.1097/AJP.0000000000000435 POPE, J. E.; FALOWSKI, S.; DEER, T. R. Advanced waveforms and frequency with spinal cord stimulation: burst and high-frequency energy delivery. Expert Review of Medical Devices, [S. l.], v. 12, n. 4, p. 431–437, 2015. Disponível em: https://doi.org/10.1586/17434440.2015.1026805 SAGHER, O.; LEVIN, E. L. Spinal Cord Stimulation. In: WINN, H. R. (org.). Youmans and Winn Nurological Surgery. 7. ed. Philadelphia: Elsevier, 2017. p. 1439–1445. E-book. SARRIS, C. Spinal Cord Stimulation Programming Strategies. In: MAMMIS, A. (org.). Spinal Cord Stimulation: Principles and Practice. 1. ed. New York: Nova Science Publishers, 2016. p. 115–121. E-book. SCHECHTMANN, G. et al. Cholinergic mechanisms involved in the pain relieving effect of spinal cord stimulation in a model of neuropathy. PAIN, [S. l.], v. 139, n. 1, p. 136–145, 2008. Disponível em: https://doi.org/10.1016/j.pain.2008.03.023 SCHU, S. et al. A Prospective, Randomised, Double-blind, Placebo-controlled Study to Examine the Effectiveness of Burst Spinal Cord Stimulation Patterns for the Treatment of Failed Back Surgery Syndrome. Neuromodulation: Technology at the Neural Interface, [S. l.], v. 17, n. 5, p. 443–450, 2014. Disponível em: https://doi.org/10.1111/ner.12197 SHEALY, C. N.; MORTIMER, J. T.; RESWICK, J. B. Electrical inhibition of pain by stimulation of the dorsal columns: preliminary clinical report. Anesthesia and analgesia, [S. l.], v. 46, n. 4, p. 489–491, 1967. SINCLAIR, C. et al. A review of spinal cord stimulation systems for chronic pain. Journal of Pain Research, [S. l.], v. 9, p. 481–492, 2016. Disponível em: https://doi.org/10.2147/JPR.S108884 SPINCEMAILLE, G. H. et al. Technical Data and Complications of Spinal Cord Stimulation: Data from a Randomized Trial on Critical Limb Ischemia. Stereotactic and Functional Neurosurgery, [S. l.], v. 74, n. 2, p. 63–72, 2000 a. 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Journal of Neurophysiology, [S. l.], v. 112, n. 3, p. 552–567, 2014. Disponível em: https://doi.org/10.1152/jn.00254.2014info:eu-repo/semantics/openAccessreponame:Repositório do Centro Universitário Braz Cubasinstname:Centro Universitário Braz Cubas (CUB)instacron:CUB2022-01-14T18:52:10Zoai:repositorio.cruzeirodosul.edu.br:123456789/1453Repositório InstitucionalPUBhttps://repositorio.brazcubas.edu.br/oai/requestbibli@brazcubas.edu.bropendoar:2022-01-14T18:52:10Repositório do Centro Universitário Braz Cubas - Centro Universitário Braz Cubas (CUB)false |
dc.title.none.fl_str_mv |
Estimulação medular epidural para o tratamento da dor crônica: uma revisão de literatura |
title |
Estimulação medular epidural para o tratamento da dor crônica: uma revisão de literatura |
spellingShingle |
Estimulação medular epidural para o tratamento da dor crônica: uma revisão de literatura Fernandes, Matheus Pereira Dor crônica Neuromodulação Medula espinhal CNPQ::CIENCIAS DA SAUDE::MEDICINA |
title_short |
Estimulação medular epidural para o tratamento da dor crônica: uma revisão de literatura |
title_full |
Estimulação medular epidural para o tratamento da dor crônica: uma revisão de literatura |
title_fullStr |
Estimulação medular epidural para o tratamento da dor crônica: uma revisão de literatura |
title_full_unstemmed |
Estimulação medular epidural para o tratamento da dor crônica: uma revisão de literatura |
title_sort |
Estimulação medular epidural para o tratamento da dor crônica: uma revisão de literatura |
author |
Fernandes, Matheus Pereira |
author_facet |
Fernandes, Matheus Pereira |
author_role |
author |
dc.contributor.none.fl_str_mv |
Andrade, Emerson Magno Fernandes de http://lattes.cnpq.br/8755121434441999 |
dc.contributor.author.fl_str_mv |
Fernandes, Matheus Pereira |
dc.subject.por.fl_str_mv |
Dor crônica Neuromodulação Medula espinhal CNPQ::CIENCIAS DA SAUDE::MEDICINA |
topic |
Dor crônica Neuromodulação Medula espinhal CNPQ::CIENCIAS DA SAUDE::MEDICINA |
description |
Introduction: According to the International Association for the Study of Pain, pain is defined as a sensitive and unpleasant experience associated with actual or potential tissue damage. According to the temporal parameters, it can be classified as acute when it exerts a defensive alert tone against an injury, and lasts less than three months; and chronic when it lasts more than three months, not exercising a biological protective role. Conservative treatment can be based on drug therapies with the use of drugs, non-invasive anesthetic techniques, physical therapy and psychotherapy. Spinal cord stimulation is a neuromodulation technique that involves surgical or percutaneous implantation of electrodes in the epidural space, in the region of the dorsal horn of the spinal cord. It consists of replacing the sensation of pain by paresthesia, through the electric current. Objectives: To describe spinal cord stimulation in the management of chronic pain; explain the functional mechanism of spinal cord stimulation, describing the technical parameters of stimulation, report how the implantation stages of the electrodes, elucidate the main indications, list the main reconstructed complications. Materials and Methods: Exploratory, descriptive, literature review type study. Data collection was carried out from August 2019 to October 2020. Results: In view of the legacy of satisfactory results, EME is a widespread technique for the treatment of painful pathologies refractory to therapies against, including the unsuccessful spinal surgery, complex regional painful syndrome, peripheral vascular disease and intractable angina. Pain scales are used to measure pain magnitude and proportion to the definition of effective therapeutic parameters. As complications are infrequent, however, occurrences of a technical or biological nature may occur. Conclusion: Neuromodulation techniques, therefore, assist in developing to adapt to the reality of patients, with modern software and judicious materials. Therefore, spinal cord stimulation is effective and safe for the treatment of chronic refractory to conventional therapy. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-10 2021-02-03T17:54:26Z 2021-02-03 2021-02-03T17:54:26Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/bachelorThesis |
format |
bachelorThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://repositorio.cruzeirodosul.edu.br/handle/123456789/1453 |
url |
https://repositorio.cruzeirodosul.edu.br/handle/123456789/1453 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
ASHMAWI, H. A.; FREIRE, G. M. G. Peripheral and central sensitization. Revista Dor, [S. l.], v. 17, n. Suppl 1, p. 31–34, 2016. Disponível em: https://doi.org/10.5935/1806-0013.20160044 BASBAUM, A. I.; JESSEL, T. M. Dor. In: KANDEL, E. R. et al. (org.). Princípios de Neurociências. 5. ed. Porto Alegre: AMGH, 2014. p. 462–482. E-book. BENDERSKY, D.; YAMPOLSKY, C. Is Spinal Cord Stimulation Safe? A Review of Its Complications. World Neurosurgery, [S. l.], v. 82, n. 6, p. 1359–1368, 2014. Disponível em: https://doi.org/10.1016/j.wneu.2013.06.012 BREIVIK, H. et al. Survey of chronic pain in Europe: Prevalence, impact on daily life, and treatment. European Journal of Pain, [S. l.], v. 10, n. 4, p. 287–287, 2006. Disponível em: https://doi.org/10.1016/j.ejpain.2005.06.009 BURCKHARDT, C. S.; ANDERSON, K. L. The Quality of Life Scale (QOLS): reliability, validity, and utilization. Health and quality of life outcomes, [S. l.], v. 1, p. 60, 2003. 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Centro Universitário de João Pessoa Brasil UNIPÊ |
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