Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literatura
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Tipo de documento: | Trabalho de conclusão de curso |
Idioma: | por |
Título da fonte: | Repositório do Centro Universitário Braz Cubas |
Texto Completo: | https://repositorio.cruzeirodosul.edu.br/handle/123456789/4145 |
Resumo: | Ischemic stroke accounts for 87% of all cerebrovascular events and is a major cause of disability and mortality worldwide. In view of this, stroke from middle vessel occlusions, i.e., occlusions of segments M2 and M3 of the middle cerebral artery, segments A2 and A3 of the anterior cerebral artery, and segments P2 and P3 of the posterior cerebral artery, account for 25% to 40% of all acute stroke cases. The current standard management, with intravenous thrombolysis, has at best a moderate clinical outcome for cases of stroke with middle vessel occlusion. Thus, these vessels have been increasingly targeted for mechanical thrombectomy, especially with the improvement of technologies and growing literature in the area. Thus, this review aims to describe the findings on the use of mechanical thrombectomy in patients with ischemic stroke with middle vessel occlusion. This research was an exploratory literature review, with qualitative analysis of the data obtained. Thirty articles were selected, dated from 2016 to 2021, with the theme in question, through the databases: Virtual Health Library and United States National Library of Medicine. For the advanced search, the descriptors were used: "Ischemic Stroke", "Thrombectomy" and "Reperfusion" combined with each other by the Boolean operator AND. Thus, it was observed that there are still no ideal clinical and imaging criteria for selection of patients with mid-vessel occlusion stroke. Moreover, most studies showed good clinical, reperfusion, and safety results, although most of them did not use the ideal parameters for mid-vessel occlusion ischemic stroke, but the parameters already used for endovascular treatment in large-vessel occlusions. Moreover, some articles bring the differences in the results generated by different techniques used in mechanical thrombectomy, but there is still a lack of larger studies that allow a comprehensive and unbiased comparison on the subject. We conclude that there are a limited but promising number of data showing the safety and efficacy of mechanical thrombectomy for medium vessel occlusion strokes, and many neurointerventionalists are already routinely offering this type of treatment, despite the lack of guidance and recommendation from guidelines. |
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Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literaturaAcidente Vascular Cerebral IsquêmicoTrombectomiaReperfusãoCNPQ::CIENCIAS DA SAUDE::MEDICINAIschemic stroke accounts for 87% of all cerebrovascular events and is a major cause of disability and mortality worldwide. In view of this, stroke from middle vessel occlusions, i.e., occlusions of segments M2 and M3 of the middle cerebral artery, segments A2 and A3 of the anterior cerebral artery, and segments P2 and P3 of the posterior cerebral artery, account for 25% to 40% of all acute stroke cases. The current standard management, with intravenous thrombolysis, has at best a moderate clinical outcome for cases of stroke with middle vessel occlusion. Thus, these vessels have been increasingly targeted for mechanical thrombectomy, especially with the improvement of technologies and growing literature in the area. Thus, this review aims to describe the findings on the use of mechanical thrombectomy in patients with ischemic stroke with middle vessel occlusion. This research was an exploratory literature review, with qualitative analysis of the data obtained. Thirty articles were selected, dated from 2016 to 2021, with the theme in question, through the databases: Virtual Health Library and United States National Library of Medicine. For the advanced search, the descriptors were used: "Ischemic Stroke", "Thrombectomy" and "Reperfusion" combined with each other by the Boolean operator AND. Thus, it was observed that there are still no ideal clinical and imaging criteria for selection of patients with mid-vessel occlusion stroke. Moreover, most studies showed good clinical, reperfusion, and safety results, although most of them did not use the ideal parameters for mid-vessel occlusion ischemic stroke, but the parameters already used for endovascular treatment in large-vessel occlusions. Moreover, some articles bring the differences in the results generated by different techniques used in mechanical thrombectomy, but there is still a lack of larger studies that allow a comprehensive and unbiased comparison on the subject. We conclude that there are a limited but promising number of data showing the safety and efficacy of mechanical thrombectomy for medium vessel occlusion strokes, and many neurointerventionalists are already routinely offering this type of treatment, despite the lack of guidance and recommendation from guidelines.O acidente vascular cerebral isquêmico (AVCI) representa 87% de todos os eventos cerebrovasculares, sendo uma causa importante de incapacidade e mortalidade no mundo. Diante disso, o AVCI de oclusões de vasos médios, ou seja, oclusões dos segmentos M2 e M3 da artéria cerebral média, segmentos A2 e A3 da artéria cerebral anterior e segmentos P2 e P3 da artéria cerebral posterior, são responsáveis por 25% a 40% de todos os casos de AVCI agudo. O atual manejo padrão, com trombólise intravenosa, tem resultado clínico, no máximo, moderado para os casos de AVCI com oclusão de vaso médio. Dessa maneira, esses vasos vêm sendo cada vez mais alvo da trombectomia mecânica, principalmente com a melhora das tecnologias e literatura crescente naárea. Dessa forma, essa revisão tem como objetivo descrever os achados do uso da trombectomia mecânica em pacientes com AVCI de oclusão de vasos médios. Essa pesquisa tratou-se de uma revisão de literatura, de caráter exploratório, com análise qualitativados dados obtidos. Foram selecionados 30 artigos, datados de 2016 a 2021, com a temática em questão, através das bases de dados: Biblioteca virtual em Saúde e United States National Library of Medicine. Para a pesquisa avançada, foram utilizados os descritores: “Ischemic Stroke”, “Thrombectomy” e “Reperfusion” combinados entre si pelo operador booleano AND. Assim, observou-se que ainda não há critérios clínicos e de imagens ideais para seleção de pacientes com AVCI de oclusão de vaso médio. Além disso, os estudos, em grande parte, mostraram bons resultados clínicos, de reperfusão e segurança, apesar de não utilizarem, em sua maioria, os parâmetros ideais para AVCI de oclusão de vaso médio, mas sim os parâmetros já utilizados para tratamento endovascular em oclusões de vasos grandes. Ademais, alguns artigos trazem as diferenças nos resultados gerados pelas diferentes técnicas usadas na trombectomia mecânica, porém ainda faltam estudos maiores e que permitam uma comparação abrangente e imparcial sobre o tema. Conclui-se que há um número limitado, porém promissor de dados que mostram a segurança e eficácia da trombectomia mecânica para AVCI de oclusão de vasos médios e muitos neurointervencionistas, já estão oferecendo, rotineiramente, esse tipo de tratamento, apesar da falta de orientação e recomendação das diretrizes.Centro Universitário de João PessoaBrasilUNIPÊAraújo, Felipe Gurgel dehttp://lattes.cnpq.br/8467992766281076Feitosa, Arthur Basto Madeira2022-11-17T12:29:48Z2022-11-192022-11-17T12:29:48Z2022-06-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bachelorThesisapplication/pdfFeitosa, Arthur Basto Madeira. Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literatura. 41 P. Trabalho de conclusão de curso (Graduação em Medicina) - Centro Universitário de João Pessoa – UNIPÊ, João Pessoa, 2022.https://repositorio.cruzeirodosul.edu.br/handle/123456789/4145porAFONSO, L. H. C.et al. 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Acesso em: 1 nov. 2021.POWERS, W. J.et al. Guidelines for the Early Management of Patients With Acute Ischemic Stroke: 2019 Update to the 2018 Guidelines for the Early Management of Acute 40Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.Stroke, [s. l.], v. 50, n. 12, p. 344-418, 2019. DOI 10.1161/STR.0000000000000211. Disponível em: https://pubmed.ncbi.nlm.nih.gov/31662037/. Acesso em: 30 ago. 2021.QURESHI 1, A. I.; SALEEM,M. A.; AYTAC,Emrah. Comparison of Endovascular Treatment with Intravenous Thrombolysis for Isolated M2 Segment of Middle Cerebral Artery Occlusion in Acute Ischemic Stroke.Journal of Vasccular and Interventional Neurology, Estados Unidos da América, v. 9, n. 5, p. 8-14, 2017. Disponível em: https://pubmed.ncbi.nlm.nih.gov/29163743/. Acesso em: 5 jan. 2022.RIKHTEGAR, Rezaet al. Effectiveness of very low profile thrombectomydevice in primary distal medium vessel occlusion, as rescue therapy after incomplete proximal recanalization or following iatrogenic thromboembolic events.Journal Neurointerventional Surgery, Alemanha, v. 13, n. 12, p. 1067-1072, 2021. DOI 10.1136/neurintsurg-2020-017035. Disponível em: https://pesquisa.bvsalud.org/portal/resource/pt/mdl-33468609. Acesso em: 3 fev. 2022.ROMANO, D. G.et al. Multicentric Experience with an Intermediate Aspiration Catheter for Distal M2 Ischemic Stroke.Journal Stroke Cerebrovascular Diseases: the official journal of National Stroke Association, Itália, v. 29, n. 12, p. 105389, 2020. DOI 10.1016/j.jstrokecerebrovasdis.2020.105389. Disponível em: https://pesquisa.bvsalud.org/portal/resource/pt/mdl-33096489. Acessoem: 3 jan. 2022.SABER, H.et al. 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DOI 10.1212/WNL.0000000000002951. Disponível em: https://pubmed.ncbi.nlm.nih.gov/27385749/. Acesso em: 1 out. 2021info:eu-repo/semantics/openAccessreponame:Repositório do Centro Universitário Braz Cubasinstname:Centro Universitário Braz Cubas (CUB)instacron:CUB2022-11-17T12:31:47Zoai:repositorio.cruzeirodosul.edu.br:123456789/4145Repositório InstitucionalPUBhttps://repositorio.brazcubas.edu.br/oai/requestbibli@brazcubas.edu.bropendoar:2022-11-17T12:31:47Repositório do Centro Universitário Braz Cubas - Centro Universitário Braz Cubas (CUB)false |
dc.title.none.fl_str_mv |
Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literatura |
title |
Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literatura |
spellingShingle |
Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literatura Feitosa, Arthur Basto Madeira Acidente Vascular Cerebral Isquêmico Trombectomia Reperfusão CNPQ::CIENCIAS DA SAUDE::MEDICINA |
title_short |
Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literatura |
title_full |
Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literatura |
title_fullStr |
Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literatura |
title_full_unstemmed |
Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literatura |
title_sort |
Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literatura |
author |
Feitosa, Arthur Basto Madeira |
author_facet |
Feitosa, Arthur Basto Madeira |
author_role |
author |
dc.contributor.none.fl_str_mv |
Araújo, Felipe Gurgel de http://lattes.cnpq.br/8467992766281076 |
dc.contributor.author.fl_str_mv |
Feitosa, Arthur Basto Madeira |
dc.subject.por.fl_str_mv |
Acidente Vascular Cerebral Isquêmico Trombectomia Reperfusão CNPQ::CIENCIAS DA SAUDE::MEDICINA |
topic |
Acidente Vascular Cerebral Isquêmico Trombectomia Reperfusão CNPQ::CIENCIAS DA SAUDE::MEDICINA |
description |
Ischemic stroke accounts for 87% of all cerebrovascular events and is a major cause of disability and mortality worldwide. In view of this, stroke from middle vessel occlusions, i.e., occlusions of segments M2 and M3 of the middle cerebral artery, segments A2 and A3 of the anterior cerebral artery, and segments P2 and P3 of the posterior cerebral artery, account for 25% to 40% of all acute stroke cases. The current standard management, with intravenous thrombolysis, has at best a moderate clinical outcome for cases of stroke with middle vessel occlusion. Thus, these vessels have been increasingly targeted for mechanical thrombectomy, especially with the improvement of technologies and growing literature in the area. Thus, this review aims to describe the findings on the use of mechanical thrombectomy in patients with ischemic stroke with middle vessel occlusion. This research was an exploratory literature review, with qualitative analysis of the data obtained. Thirty articles were selected, dated from 2016 to 2021, with the theme in question, through the databases: Virtual Health Library and United States National Library of Medicine. For the advanced search, the descriptors were used: "Ischemic Stroke", "Thrombectomy" and "Reperfusion" combined with each other by the Boolean operator AND. Thus, it was observed that there are still no ideal clinical and imaging criteria for selection of patients with mid-vessel occlusion stroke. Moreover, most studies showed good clinical, reperfusion, and safety results, although most of them did not use the ideal parameters for mid-vessel occlusion ischemic stroke, but the parameters already used for endovascular treatment in large-vessel occlusions. Moreover, some articles bring the differences in the results generated by different techniques used in mechanical thrombectomy, but there is still a lack of larger studies that allow a comprehensive and unbiased comparison on the subject. We conclude that there are a limited but promising number of data showing the safety and efficacy of mechanical thrombectomy for medium vessel occlusion strokes, and many neurointerventionalists are already routinely offering this type of treatment, despite the lack of guidance and recommendation from guidelines. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-11-17T12:29:48Z 2022-11-19 2022-11-17T12:29:48Z 2022-06-15 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/bachelorThesis |
format |
bachelorThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Feitosa, Arthur Basto Madeira. Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literatura. 41 P. Trabalho de conclusão de curso (Graduação em Medicina) - Centro Universitário de João Pessoa – UNIPÊ, João Pessoa, 2022. https://repositorio.cruzeirodosul.edu.br/handle/123456789/4145 |
identifier_str_mv |
Feitosa, Arthur Basto Madeira. Expandindo o uso da trombectomia mecânica no acidente vascular cerebral isquêmico: uma revisão de literatura. 41 P. Trabalho de conclusão de curso (Graduação em Medicina) - Centro Universitário de João Pessoa – UNIPÊ, João Pessoa, 2022. |
url |
https://repositorio.cruzeirodosul.edu.br/handle/123456789/4145 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
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DOI 10.1016/j.wneu.2016.11.035. Disponível em: https://pesquisa.bvsalud.org/portal/resource/pt/mdl-27913263. Acesso em: 1 out. 2021.VELASCO, Irineu Tadeu et al. Medicina de Emergência: Abordagem Prática. 14a ed. Barueri, MANOLE, 2020.YU, A. Y. X.et al. Multiphase CT angiography increases detection of anterior circulation intracranial occlusion.Neurology, [s. l.], v. 87, n. 6, p. 609-16, 9 ago. 2016. DOI 10.1212/WNL.0000000000002951. Disponível em: https://pubmed.ncbi.nlm.nih.gov/27385749/. Acesso em: 1 out. 2021 |
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