Estudo de aterosclerose e fatores de risco em pacientes portadores de HTLV-1
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Tipo de documento: | Dissertação |
Idioma: | por |
Título da fonte: | Repositório Institucional da Escola Bahiana de Medicina e Saúde Pública |
Texto Completo: | http://www7.bahiana.edu.br//jspui/handle/bahiana/78 |
Resumo: | HTLV-1 infection induces a systemic inflammation and occasionally is associated with co infections. Atherosclerosis is closely related to the inflammatory process and its progression lasts for decades. Objectives: 1) To study the risk factors for cardiovascular diseases and atherosclerosis in patients infected by HTLV-1 . 2) To identify the thickening of the intimal-medial layer. 3) To evaluate the association between intimal thickening of the intima , the presence of HAM / TSP , ultrasensitive C-reactive protein and cardiovascular risk factors (age, sex, hypertension , hypercholesterolemia , diabetes mellitus and smoking).Study Design: Cross-sectional observational study. Methods: this study was carried out at the Center for HTLV / EBMSP, Salvador, Brazil, in the period between April, 2012 to September, 2013 The outcome of interest was the presence of atherosclerosis. Sociodemographic and cardiovascular risk factors were evaluated. Results 54 patients were enrolled, with a mean age (SD) of 57.06 (12.33) years, median (p25 - p75) to 57 (46.8 to 65.0) years and predominantly composed of women (72.2%), 41% of women and 3% of men had atherosclerosis. Conclusions: No association was observed between HTLV-1 and clinical or subclinical atherosclerosis as well as with the risk for cardiovascular diseases. A positive association between atherosclerosis and age was observed. |
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Dória, Glauco Moniz de AragãoCastro Filho, Bernardo GalvãoDurães, André RodriguesGarcia, Maristela Magnavita OliveiraBoa Sorte, Ney Cristian Amaral2015-04-14T02:26:45Z2015-04-14T02:26:45Z2014http://www7.bahiana.edu.br//jspui/handle/bahiana/78HTLV-1 infection induces a systemic inflammation and occasionally is associated with co infections. Atherosclerosis is closely related to the inflammatory process and its progression lasts for decades. Objectives: 1) To study the risk factors for cardiovascular diseases and atherosclerosis in patients infected by HTLV-1 . 2) To identify the thickening of the intimal-medial layer. 3) To evaluate the association between intimal thickening of the intima , the presence of HAM / TSP , ultrasensitive C-reactive protein and cardiovascular risk factors (age, sex, hypertension , hypercholesterolemia , diabetes mellitus and smoking).Study Design: Cross-sectional observational study. Methods: this study was carried out at the Center for HTLV / EBMSP, Salvador, Brazil, in the period between April, 2012 to September, 2013 The outcome of interest was the presence of atherosclerosis. Sociodemographic and cardiovascular risk factors were evaluated. Results 54 patients were enrolled, with a mean age (SD) of 57.06 (12.33) years, median (p25 - p75) to 57 (46.8 to 65.0) years and predominantly composed of women (72.2%), 41% of women and 3% of men had atherosclerosis. Conclusions: No association was observed between HTLV-1 and clinical or subclinical atherosclerosis as well as with the risk for cardiovascular diseases. A positive association between atherosclerosis and age was observed.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2015-04-14T02:26:45Z No. of bitstreams: 1 GLAUCO MONIZ DE ARAGÃO DORIA.pdf: 389847 bytes, checksum: 2db42741df4e78cf56b5fa498d43cc57 (MD5)Made available in DSpace on 2015-04-14T02:26:45Z (GMT). No. of bitstreams: 1 GLAUCO MONIZ DE ARAGÃO DORIA.pdf: 389847 bytes, checksum: 2db42741df4e78cf56b5fa498d43cc57 (MD5) Previous issue date: 2014Escola de Medicina e Saúde PúblicaPós-Graduação de Mestrado e Doutorado em Medicina e Saúde HumanaEBMSPbrasilHTLVAtherosclerosisEstudo de aterosclerose e fatores de risco em pacientes portadores de HTLV-1info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisinfo:eu-repo/semantics/openAccessporreponame:Repositório Institucional da Escola Bahiana de Medicina e Saúde Públicainstname:EBMinstacron:EBMORIGINALGLAUCO MONIZ DE ARAGÃO DORIA.pdfGLAUCO MONIZ DE ARAGÃO DORIA.pdfapplication/pdf389847http://www7.bahiana.edu.br//jspui/bitstream/bahiana/78/1/GLAUCO+MONIZ+DE+ARAG%C3%83O+DORIA.pdf2db42741df4e78cf56b5fa498d43cc57MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-81748http://www7.bahiana.edu.br//jspui/bitstream/bahiana/78/2/license.txt8a4605be74aa9ea9d79846c1fba20a33MD52bahiana/78oai:www7.bahiana.edu.br:bahiana/782015-04-13 23:26:45.428Repositório Institucional - Escola Bahiana de Medicina e Saúde Públicarepositorio@bahiana.edu.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 |
dc.title.pt_BR.fl_str_mv |
Estudo de aterosclerose e fatores de risco em pacientes portadores de HTLV-1 |
title |
Estudo de aterosclerose e fatores de risco em pacientes portadores de HTLV-1 |
spellingShingle |
Estudo de aterosclerose e fatores de risco em pacientes portadores de HTLV-1 Dória, Glauco Moniz de Aragão HTLV Atherosclerosis |
title_short |
Estudo de aterosclerose e fatores de risco em pacientes portadores de HTLV-1 |
title_full |
Estudo de aterosclerose e fatores de risco em pacientes portadores de HTLV-1 |
title_fullStr |
Estudo de aterosclerose e fatores de risco em pacientes portadores de HTLV-1 |
title_full_unstemmed |
Estudo de aterosclerose e fatores de risco em pacientes portadores de HTLV-1 |
title_sort |
Estudo de aterosclerose e fatores de risco em pacientes portadores de HTLV-1 |
author |
Dória, Glauco Moniz de Aragão |
author_facet |
Dória, Glauco Moniz de Aragão |
author_role |
author |
dc.contributor.author.fl_str_mv |
Dória, Glauco Moniz de Aragão |
dc.contributor.advisor1.fl_str_mv |
Castro Filho, Bernardo Galvão |
dc.contributor.referee1.fl_str_mv |
Durães, André Rodrigues Garcia, Maristela Magnavita Oliveira Boa Sorte, Ney Cristian Amaral |
contributor_str_mv |
Castro Filho, Bernardo Galvão Durães, André Rodrigues Garcia, Maristela Magnavita Oliveira Boa Sorte, Ney Cristian Amaral |
dc.subject.por.fl_str_mv |
HTLV Atherosclerosis |
topic |
HTLV Atherosclerosis |
dc.description.abstract.por.fl_txt_mv |
HTLV-1 infection induces a systemic inflammation and occasionally is associated with co infections. Atherosclerosis is closely related to the inflammatory process and its progression lasts for decades. Objectives: 1) To study the risk factors for cardiovascular diseases and atherosclerosis in patients infected by HTLV-1 . 2) To identify the thickening of the intimal-medial layer. 3) To evaluate the association between intimal thickening of the intima , the presence of HAM / TSP , ultrasensitive C-reactive protein and cardiovascular risk factors (age, sex, hypertension , hypercholesterolemia , diabetes mellitus and smoking).Study Design: Cross-sectional observational study. Methods: this study was carried out at the Center for HTLV / EBMSP, Salvador, Brazil, in the period between April, 2012 to September, 2013 The outcome of interest was the presence of atherosclerosis. Sociodemographic and cardiovascular risk factors were evaluated. Results 54 patients were enrolled, with a mean age (SD) of 57.06 (12.33) years, median (p25 - p75) to 57 (46.8 to 65.0) years and predominantly composed of women (72.2%), 41% of women and 3% of men had atherosclerosis. Conclusions: No association was observed between HTLV-1 and clinical or subclinical atherosclerosis as well as with the risk for cardiovascular diseases. A positive association between atherosclerosis and age was observed. |
description |
HTLV-1 infection induces a systemic inflammation and occasionally is associated with co infections. Atherosclerosis is closely related to the inflammatory process and its progression lasts for decades. Objectives: 1) To study the risk factors for cardiovascular diseases and atherosclerosis in patients infected by HTLV-1 . 2) To identify the thickening of the intimal-medial layer. 3) To evaluate the association between intimal thickening of the intima , the presence of HAM / TSP , ultrasensitive C-reactive protein and cardiovascular risk factors (age, sex, hypertension , hypercholesterolemia , diabetes mellitus and smoking).Study Design: Cross-sectional observational study. Methods: this study was carried out at the Center for HTLV / EBMSP, Salvador, Brazil, in the period between April, 2012 to September, 2013 The outcome of interest was the presence of atherosclerosis. Sociodemographic and cardiovascular risk factors were evaluated. Results 54 patients were enrolled, with a mean age (SD) of 57.06 (12.33) years, median (p25 - p75) to 57 (46.8 to 65.0) years and predominantly composed of women (72.2%), 41% of women and 3% of men had atherosclerosis. Conclusions: No association was observed between HTLV-1 and clinical or subclinical atherosclerosis as well as with the risk for cardiovascular diseases. A positive association between atherosclerosis and age was observed. |
publishDate |
2014 |
dc.date.issued.fl_str_mv |
2014 |
dc.date.accessioned.fl_str_mv |
2015-04-14T02:26:45Z |
dc.date.available.fl_str_mv |
2015-04-14T02:26:45Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
status_str |
publishedVersion |
format |
masterThesis |
dc.identifier.uri.fl_str_mv |
http://www7.bahiana.edu.br//jspui/handle/bahiana/78 |
url |
http://www7.bahiana.edu.br//jspui/handle/bahiana/78 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Escola de Medicina e Saúde Pública |
dc.publisher.program.fl_str_mv |
Pós-Graduação de Mestrado e Doutorado em Medicina e Saúde Humana |
dc.publisher.initials.fl_str_mv |
EBMSP |
dc.publisher.country.fl_str_mv |
brasil |
publisher.none.fl_str_mv |
Escola de Medicina e Saúde Pública |
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