Studies on the "ERA" strain of rabies virus in Brazil. I. Distribution of the virus in the organism of inoculated cattle and formation of inclusions in the central nervous system

Detalhes bibliográficos
Autor(a) principal: Silva, Renato Augusto da
Data de Publicação: 2014
Outros Autores: Silva, Norma Moraes da, Menezes, Patino Roberto Valadão
Tipo de documento: Artigo
Idioma: por
Título da fonte: Pesquisa Agropecuária Brasileira (Online)
Texto Completo: https://seer.sct.embrapa.br/index.php/pab/article/view/17225
Resumo: Rabies virus, "ERA" strain, inoculated by intra-muscular route into the masseter muscle was capable of localizing in the salivary glands, brain, cerebellum, bulbus and spinal cord. The "ERA" strain determined the appearence of inclusions, in the cytoplasm of the neurons of bulbus and spinal cord, which resembled Negri bodies. Fine granular acidophile material diffusely dispersed in the cytoplasm was encountered. The viral rabies antigen was detected in high concentration in the bulbus, spinal cord and salivary glands, by fluorescent antibodies techniques. The rabies virus was not recovered from the nervous tissues, salivary glands saliva of mice.
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spelling Studies on the "ERA" strain of rabies virus in Brazil. I. Distribution of the virus in the organism of inoculated cattle and formation of inclusions in the central nervous systemEnsaios com o vírus rábico "ERA", no Brasil. I. Distribuição do vírus no organismo de bovinos inoculados e formação de inclusões no sistema nervoso centralRabiesRaivaRabies virus, "ERA" strain, inoculated by intra-muscular route into the masseter muscle was capable of localizing in the salivary glands, brain, cerebellum, bulbus and spinal cord. The "ERA" strain determined the appearence of inclusions, in the cytoplasm of the neurons of bulbus and spinal cord, which resembled Negri bodies. Fine granular acidophile material diffusely dispersed in the cytoplasm was encountered. The viral rabies antigen was detected in high concentration in the bulbus, spinal cord and salivary glands, by fluorescent antibodies techniques. The rabies virus was not recovered from the nervous tissues, salivary glands saliva of mice.A amostra de vírus rábido ERA, inoculada por via intramuscular em bovinos, no masseter, foi capaz de se localizar nos tecidos das glândulas salivares (submaxilares, parótidas e sublinguais) e no sistema nervoso central. A amostra ERA determinou o aparecimento de inclusões no citoplasma e nos prolongamentos dos neurônios dos bovinos, muito semelhantes aos corpúsculos de Negri. Material acidófilo finamente granular, espalhado difusamente no citoplasma celular, pôde ser observado. Os camundongos que receberam intracranialmente a amostra ERA também mostraram inclusões muito semelhantes aos corpúsculos de Negri no citoplasma de suas células nervosas. O antígeno rábico nos tecidos glandular e nervoso foi evidenciado pelo teste de anticorpos fluorescentes. Não se recuperou vírus dos tecidos imuno-positivos, nem da saliva, por inoculação em camundongos adultos e lactentes.Pesquisa Agropecuaria BrasileiraPesquisa Agropecuária BrasileiraSilva, Renato Augusto daSilva, Norma Moraes daMenezes, Patino Roberto Valadão2014-04-15info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://seer.sct.embrapa.br/index.php/pab/article/view/17225Pesquisa Agropecuaria Brasileira; v.9, n.7, 1974: Série Veterinária; 49-52Pesquisa Agropecuária Brasileira; v.9, n.7, 1974: Série Veterinária; 49-521678-39210100-104xreponame:Pesquisa Agropecuária Brasileira (Online)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPAporhttps://seer.sct.embrapa.br/index.php/pab/article/view/17225/11539info:eu-repo/semantics/openAccess2014-04-15T18:57:58Zoai:ojs.seer.sct.embrapa.br:article/17225Revistahttp://seer.sct.embrapa.br/index.php/pabPRIhttps://old.scielo.br/oai/scielo-oai.phppab@sct.embrapa.br || sct.pab@embrapa.br1678-39210100-204Xopendoar:2014-04-15T18:57:58Pesquisa Agropecuária Brasileira (Online) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false
dc.title.none.fl_str_mv Studies on the "ERA" strain of rabies virus in Brazil. I. Distribution of the virus in the organism of inoculated cattle and formation of inclusions in the central nervous system
Ensaios com o vírus rábico "ERA", no Brasil. I. Distribuição do vírus no organismo de bovinos inoculados e formação de inclusões no sistema nervoso central
title Studies on the "ERA" strain of rabies virus in Brazil. I. Distribution of the virus in the organism of inoculated cattle and formation of inclusions in the central nervous system
spellingShingle Studies on the "ERA" strain of rabies virus in Brazil. I. Distribution of the virus in the organism of inoculated cattle and formation of inclusions in the central nervous system
Silva, Renato Augusto da
Rabies
Raiva
title_short Studies on the "ERA" strain of rabies virus in Brazil. I. Distribution of the virus in the organism of inoculated cattle and formation of inclusions in the central nervous system
title_full Studies on the "ERA" strain of rabies virus in Brazil. I. Distribution of the virus in the organism of inoculated cattle and formation of inclusions in the central nervous system
title_fullStr Studies on the "ERA" strain of rabies virus in Brazil. I. Distribution of the virus in the organism of inoculated cattle and formation of inclusions in the central nervous system
title_full_unstemmed Studies on the "ERA" strain of rabies virus in Brazil. I. Distribution of the virus in the organism of inoculated cattle and formation of inclusions in the central nervous system
title_sort Studies on the "ERA" strain of rabies virus in Brazil. I. Distribution of the virus in the organism of inoculated cattle and formation of inclusions in the central nervous system
author Silva, Renato Augusto da
author_facet Silva, Renato Augusto da
Silva, Norma Moraes da
Menezes, Patino Roberto Valadão
author_role author
author2 Silva, Norma Moraes da
Menezes, Patino Roberto Valadão
author2_role author
author
dc.contributor.none.fl_str_mv

dc.contributor.author.fl_str_mv Silva, Renato Augusto da
Silva, Norma Moraes da
Menezes, Patino Roberto Valadão
dc.subject.por.fl_str_mv Rabies
Raiva
topic Rabies
Raiva
description Rabies virus, "ERA" strain, inoculated by intra-muscular route into the masseter muscle was capable of localizing in the salivary glands, brain, cerebellum, bulbus and spinal cord. The "ERA" strain determined the appearence of inclusions, in the cytoplasm of the neurons of bulbus and spinal cord, which resembled Negri bodies. Fine granular acidophile material diffusely dispersed in the cytoplasm was encountered. The viral rabies antigen was detected in high concentration in the bulbus, spinal cord and salivary glands, by fluorescent antibodies techniques. The rabies virus was not recovered from the nervous tissues, salivary glands saliva of mice.
publishDate 2014
dc.date.none.fl_str_mv 2014-04-15
dc.type.none.fl_str_mv
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://seer.sct.embrapa.br/index.php/pab/article/view/17225
url https://seer.sct.embrapa.br/index.php/pab/article/view/17225
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://seer.sct.embrapa.br/index.php/pab/article/view/17225/11539
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Pesquisa Agropecuaria Brasileira
Pesquisa Agropecuária Brasileira
publisher.none.fl_str_mv Pesquisa Agropecuaria Brasileira
Pesquisa Agropecuária Brasileira
dc.source.none.fl_str_mv Pesquisa Agropecuaria Brasileira; v.9, n.7, 1974: Série Veterinária; 49-52
Pesquisa Agropecuária Brasileira; v.9, n.7, 1974: Série Veterinária; 49-52
1678-3921
0100-104x
reponame:Pesquisa Agropecuária Brasileira (Online)
instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
instname_str Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Pesquisa Agropecuária Brasileira (Online)
collection Pesquisa Agropecuária Brasileira (Online)
repository.name.fl_str_mv Pesquisa Agropecuária Brasileira (Online) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
repository.mail.fl_str_mv pab@sct.embrapa.br || sct.pab@embrapa.br
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