Brazilian irradiated vaccine compared to british commercial vaccine "Dictol", against Dictyocaulus viviparus

• Autor(a) principal: Gennari, Solange Maria
• Data de Publicação: 2014
• Outros Autores: Duncan, James L.
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Pesquisa Agropecuária Brasileira (Online)
• Texto Completo: https://seer.sct.embrapa.br/index.php/pab/article/view/15396
• topic: bovine helminthosis; helmintose bovina

This study was carried out at the Divisão de Ciências Animais of the Centro de Energia Nuclear para a Agricultura (CENA). in Piracicaba, SP, Brazil, to test and compare the immunity produced by the use of vaccine prepared at the CENA using gamma irradiation and the British comrnercial Dictol against Dictyocaulus viviporus (Block 1782). Eighteen calves were divided into three groups, each with six animals: group A received Dictol; group B, the gamma irradiated vaccine; and C, without vaccine, was the control group. Two doses were given orally with a tour-week interval. One month after the second dose the calves were challenged with D. viviparus larvae at the rate of 60 larvae per kg of body weight, and five weeks later all animals were killed. The number of lungworms was then determined. There was little difference between treatments A and B, but both had significantly reduced challenge worm burdens compared with group C, i.e. 84% for Dictol and 86% for CENA vaccinates. The clinical symptoms of husk were present in the three treatments, but they were minimal in the vaccinated animals. Both vaccines were efficient in the immunization of calves against D. viviparus.