Association of apolipoprotein B and adiponectin receptor 1 genes with carcass, bone integrity and performance traits in a paternal broiler Line.

Detalhes bibliográficos
Autor(a) principal: CRUZ, V. A. R. da
Data de Publicação: 2015
Outros Autores: SCHENKEL, F. S., SAVEGNAGO, R. P., GRUPIONI, N. V., STAFUZZA, N. B., SARGOZAEL, M., IBELLI, A. M. G., PEIXOTO, J. de O., LEDUR, M. C., MUNARI, D. P.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
Texto Completo: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1025860
Resumo: Apolipoprotein B (APOB) and Adiponectin Receptor 1 (ADIPOR1) are related to the regulation of feed intake, fat metabolism and protein deposition and are candidate genes for genomic studies in birds. In this study, associations of two single nucleotide polymorphisms (SNPs) g.102A>T (APOB) and g.729C>T (ADIPOR1) with carcass, bone integrity and performance traits in broilers were investigated. Genotyping was performed on a paternal line of 1,454 broilers. The SNP detection was carried out by PCR-RFLP technique using the restriction enzymes HhaI for the SNP g.729C>T and MslI for the SNP g.102A>T. The association analyses of the two SNPs with 85 traits were performed using the restricted maximum likelihood (REML) and Generalized Quasi-Likelihood Score (GQLS) methods. For REML the model included the random additive genetic effect of animal and fixed effects of sex, hatch and SNP genotypes. In the GQLS method, a logistic regression was used to associate the genotypes with phenotypes adjusted for fixed effects of sex and hatch. The SNP g.729C>T in the ADIPOR1 gene was associated with thickness of the femur and breast skin yield. Thus, the ADIPOR1 gene seems implicated in the metabolism and/or fat deposition and bone integrity in broilers.
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spelling Association of apolipoprotein B and adiponectin receptor 1 genes with carcass, bone integrity and performance traits in a paternal broiler Line.Frango de corteCarcaçaGenética animalApolipoprotein B (APOB) and Adiponectin Receptor 1 (ADIPOR1) are related to the regulation of feed intake, fat metabolism and protein deposition and are candidate genes for genomic studies in birds. In this study, associations of two single nucleotide polymorphisms (SNPs) g.102A>T (APOB) and g.729C>T (ADIPOR1) with carcass, bone integrity and performance traits in broilers were investigated. Genotyping was performed on a paternal line of 1,454 broilers. The SNP detection was carried out by PCR-RFLP technique using the restriction enzymes HhaI for the SNP g.729C>T and MslI for the SNP g.102A>T. The association analyses of the two SNPs with 85 traits were performed using the restricted maximum likelihood (REML) and Generalized Quasi-Likelihood Score (GQLS) methods. For REML the model included the random additive genetic effect of animal and fixed effects of sex, hatch and SNP genotypes. In the GQLS method, a logistic regression was used to associate the genotypes with phenotypes adjusted for fixed effects of sex and hatch. The SNP g.729C>T in the ADIPOR1 gene was associated with thickness of the femur and breast skin yield. Thus, the ADIPOR1 gene seems implicated in the metabolism and/or fat deposition and bone integrity in broilers.VALDECY APARECIDA ROCHA DA CRUZ, UNESP; FLÁVIO SCHRAMM SCHENKEL, University of Guelph; RODRIGO PELICIONI SAVEGNAGO, UNESP; NATALIA VINHAL GRUPIONI, UNESP; NEDENIA BONVINO STAFUZZA, UNESP; MEHDI SARGOLZAEL, The Semex Alliance; ADRIANA MERCIA GUARATINI IBELLI, CNPSA; JANE DE OLIVEIRA PEIXOTO, CNPSA; MONICA CORREA LEDUR, CNPSA; DANÍSIO PRADO MUNARI, UNESP.CRUZ, V. A. R. daSCHENKEL, F. S.SAVEGNAGO, R. P.GRUPIONI, N. V.STAFUZZA, N. B.SARGOZAEL, M.IBELLI, A. M. G.PEIXOTO, J. de O.LEDUR, M. C.MUNARI, D. P.2018-05-11T00:40:51Z2018-05-11T00:40:51Z2015-10-0620152018-05-11T00:40:51Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlePlos One, v. 10, n.8, 2015.http://www.alice.cnptia.embrapa.br/alice/handle/doc/102586010.1371/journal.pone.0136824enginfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPA2018-05-11T00:40:57Zoai:www.alice.cnptia.embrapa.br:doc/1025860Repositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestopendoar:21542018-05-11T00:40:57falseRepositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestcg-riaa@embrapa.bropendoar:21542018-05-11T00:40:57Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false
dc.title.none.fl_str_mv Association of apolipoprotein B and adiponectin receptor 1 genes with carcass, bone integrity and performance traits in a paternal broiler Line.
title Association of apolipoprotein B and adiponectin receptor 1 genes with carcass, bone integrity and performance traits in a paternal broiler Line.
spellingShingle Association of apolipoprotein B and adiponectin receptor 1 genes with carcass, bone integrity and performance traits in a paternal broiler Line.
CRUZ, V. A. R. da
Frango de corte
Carcaça
Genética animal
title_short Association of apolipoprotein B and adiponectin receptor 1 genes with carcass, bone integrity and performance traits in a paternal broiler Line.
title_full Association of apolipoprotein B and adiponectin receptor 1 genes with carcass, bone integrity and performance traits in a paternal broiler Line.
title_fullStr Association of apolipoprotein B and adiponectin receptor 1 genes with carcass, bone integrity and performance traits in a paternal broiler Line.
title_full_unstemmed Association of apolipoprotein B and adiponectin receptor 1 genes with carcass, bone integrity and performance traits in a paternal broiler Line.
title_sort Association of apolipoprotein B and adiponectin receptor 1 genes with carcass, bone integrity and performance traits in a paternal broiler Line.
author CRUZ, V. A. R. da
author_facet CRUZ, V. A. R. da
SCHENKEL, F. S.
SAVEGNAGO, R. P.
GRUPIONI, N. V.
STAFUZZA, N. B.
SARGOZAEL, M.
IBELLI, A. M. G.
PEIXOTO, J. de O.
LEDUR, M. C.
MUNARI, D. P.
author_role author
author2 SCHENKEL, F. S.
SAVEGNAGO, R. P.
GRUPIONI, N. V.
STAFUZZA, N. B.
SARGOZAEL, M.
IBELLI, A. M. G.
PEIXOTO, J. de O.
LEDUR, M. C.
MUNARI, D. P.
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv VALDECY APARECIDA ROCHA DA CRUZ, UNESP; FLÁVIO SCHRAMM SCHENKEL, University of Guelph; RODRIGO PELICIONI SAVEGNAGO, UNESP; NATALIA VINHAL GRUPIONI, UNESP; NEDENIA BONVINO STAFUZZA, UNESP; MEHDI SARGOLZAEL, The Semex Alliance; ADRIANA MERCIA GUARATINI IBELLI, CNPSA; JANE DE OLIVEIRA PEIXOTO, CNPSA; MONICA CORREA LEDUR, CNPSA; DANÍSIO PRADO MUNARI, UNESP.
dc.contributor.author.fl_str_mv CRUZ, V. A. R. da
SCHENKEL, F. S.
SAVEGNAGO, R. P.
GRUPIONI, N. V.
STAFUZZA, N. B.
SARGOZAEL, M.
IBELLI, A. M. G.
PEIXOTO, J. de O.
LEDUR, M. C.
MUNARI, D. P.
dc.subject.por.fl_str_mv Frango de corte
Carcaça
Genética animal
topic Frango de corte
Carcaça
Genética animal
description Apolipoprotein B (APOB) and Adiponectin Receptor 1 (ADIPOR1) are related to the regulation of feed intake, fat metabolism and protein deposition and are candidate genes for genomic studies in birds. In this study, associations of two single nucleotide polymorphisms (SNPs) g.102A>T (APOB) and g.729C>T (ADIPOR1) with carcass, bone integrity and performance traits in broilers were investigated. Genotyping was performed on a paternal line of 1,454 broilers. The SNP detection was carried out by PCR-RFLP technique using the restriction enzymes HhaI for the SNP g.729C>T and MslI for the SNP g.102A>T. The association analyses of the two SNPs with 85 traits were performed using the restricted maximum likelihood (REML) and Generalized Quasi-Likelihood Score (GQLS) methods. For REML the model included the random additive genetic effect of animal and fixed effects of sex, hatch and SNP genotypes. In the GQLS method, a logistic regression was used to associate the genotypes with phenotypes adjusted for fixed effects of sex and hatch. The SNP g.729C>T in the ADIPOR1 gene was associated with thickness of the femur and breast skin yield. Thus, the ADIPOR1 gene seems implicated in the metabolism and/or fat deposition and bone integrity in broilers.
publishDate 2015
dc.date.none.fl_str_mv 2015-10-06
2015
2018-05-11T00:40:51Z
2018-05-11T00:40:51Z
2018-05-11T00:40:51Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Plos One, v. 10, n.8, 2015.
http://www.alice.cnptia.embrapa.br/alice/handle/doc/1025860
10.1371/journal.pone.0136824
identifier_str_mv Plos One, v. 10, n.8, 2015.
10.1371/journal.pone.0136824
url http://www.alice.cnptia.embrapa.br/alice/handle/doc/1025860
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
instname_str Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
collection Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
repository.name.fl_str_mv Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
repository.mail.fl_str_mv cg-riaa@embrapa.br
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