Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.

Detalhes bibliográficos
Autor(a) principal: OLIVEIRA JÚNIOR, R. G. de
Data de Publicação: 2018
Outros Autores: FERRAZ, C. A. A., SILVA, J. C., TELES. R. B. de A., SILVA, M. G., DINIZ, T. C., SANTOS, U. S. dos, SOUZA, A. V. de, NUNES, C. E. P., SALVADOR, M. J., LORENZO, V. P., QUINTANS JÚNIOR, L. J., ALMEIDA, J. R. G. da S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
Texto Completo: http://www.alice.cnptia.embrapa.br/alice/handle/doc/1090904
Resumo: Ethnopharmacological relevance: Croton conduplicatus Kunth (Euphorbiaceae) is a Brazilian aromatic medicinal plant, widely known as ?quebra-faca?. In folk medicine, its leaves and stem-barks are used as a natural analgesic for the treatment of headaches. Aim of the study: In this study, we describe for the first time the neuropharmacological potential of the essential oil obtained from the leaves of Croton conduplicatus (EO) in experimental models of pain, anxiety and insomnia. The mechanisms of action involved in these activities were also investigated.
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spelling Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.AnsiedadeDorInsôniaBioma CaatingaPlanta nativaQuebra facaEssential oilInsomniaÓleo essencialPlanta medicinalRecurso naturalAnxietyPainMedicinal plantsEthnopharmacological relevance: Croton conduplicatus Kunth (Euphorbiaceae) is a Brazilian aromatic medicinal plant, widely known as ?quebra-faca?. In folk medicine, its leaves and stem-barks are used as a natural analgesic for the treatment of headaches. Aim of the study: In this study, we describe for the first time the neuropharmacological potential of the essential oil obtained from the leaves of Croton conduplicatus (EO) in experimental models of pain, anxiety and insomnia. The mechanisms of action involved in these activities were also investigated.RAIMUNDO GONÇALVES DE OLIVEIRA JÚNIOR, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; CHRISTIANE ADRIELLY ALVES FERRAZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; JULIANE CABRAL SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; ROXANA BRAGA DE ANDRADE TELES, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; MARIANA GAMA SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; TÂMARA COIMBRA DINIZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; UILIANE SOARES DOS SANTOS; ANA VALERIA VIEIRA DE SOUZA, CPATSA; CARLOS EDUARDO PEREIRA NUNES, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; MARCOS JOSÉ SALVADOR, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; VITOR PRATES LORENZO, Instituto Federal de Educação, Ciência e Tecnologia Sertão Pernambucano, Petrolina, PE; LUCINDO JOSÉ QUINTANS JÚNIOR, Departamento de Fisiologia, Universidade Federal de Sergipe (UFS), São Cristóvão, Sergipe; JACKSON ROBERTO GUEDES DA SILVA ALMEIDA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE.OLIVEIRA JÚNIOR, R. G. deFERRAZ, C. A. A.SILVA, J. C.TELES. R. B. de A.SILVA, M. G.DINIZ, T. C.SANTOS, U. S. dosSOUZA, A. V. deNUNES, C. E. P.SALVADOR, M. J.LORENZO, V. P.QUINTANS JÚNIOR, L. J.ALMEIDA, J. R. G. da S.2018-04-27T00:37:57Z2018-04-27T00:37:57Z2018-04-2620182018-05-02T11:11:11Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleJournal of Ethnopharmacology, v. 221, p. 65–76, 2018.http://www.alice.cnptia.embrapa.br/alice/handle/doc/109090410.1016/j.jep.2018.04.009enginfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPA2018-04-27T00:38:04Zoai:www.alice.cnptia.embrapa.br:doc/1090904Repositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestopendoar:21542018-04-27T00:38:04falseRepositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestcg-riaa@embrapa.bropendoar:21542018-04-27T00:38:04Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false
dc.title.none.fl_str_mv Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.
title Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.
spellingShingle Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.
OLIVEIRA JÚNIOR, R. G. de
Ansiedade
Dor
Insônia
Bioma Caatinga
Planta nativa
Quebra faca
Essential oil
Insomnia
Óleo essencial
Planta medicinal
Recurso natural
Anxiety
Pain
Medicinal plants
title_short Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.
title_full Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.
title_fullStr Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.
title_full_unstemmed Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.
title_sort Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.
author OLIVEIRA JÚNIOR, R. G. de
author_facet OLIVEIRA JÚNIOR, R. G. de
FERRAZ, C. A. A.
SILVA, J. C.
TELES. R. B. de A.
SILVA, M. G.
DINIZ, T. C.
SANTOS, U. S. dos
SOUZA, A. V. de
NUNES, C. E. P.
SALVADOR, M. J.
LORENZO, V. P.
QUINTANS JÚNIOR, L. J.
ALMEIDA, J. R. G. da S.
author_role author
author2 FERRAZ, C. A. A.
SILVA, J. C.
TELES. R. B. de A.
SILVA, M. G.
DINIZ, T. C.
SANTOS, U. S. dos
SOUZA, A. V. de
NUNES, C. E. P.
SALVADOR, M. J.
LORENZO, V. P.
QUINTANS JÚNIOR, L. J.
ALMEIDA, J. R. G. da S.
author2_role author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv RAIMUNDO GONÇALVES DE OLIVEIRA JÚNIOR, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; CHRISTIANE ADRIELLY ALVES FERRAZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; JULIANE CABRAL SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; ROXANA BRAGA DE ANDRADE TELES, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; MARIANA GAMA SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; TÂMARA COIMBRA DINIZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; UILIANE SOARES DOS SANTOS; ANA VALERIA VIEIRA DE SOUZA, CPATSA; CARLOS EDUARDO PEREIRA NUNES, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; MARCOS JOSÉ SALVADOR, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; VITOR PRATES LORENZO, Instituto Federal de Educação, Ciência e Tecnologia Sertão Pernambucano, Petrolina, PE; LUCINDO JOSÉ QUINTANS JÚNIOR, Departamento de Fisiologia, Universidade Federal de Sergipe (UFS), São Cristóvão, Sergipe; JACKSON ROBERTO GUEDES DA SILVA ALMEIDA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE.
dc.contributor.author.fl_str_mv OLIVEIRA JÚNIOR, R. G. de
FERRAZ, C. A. A.
SILVA, J. C.
TELES. R. B. de A.
SILVA, M. G.
DINIZ, T. C.
SANTOS, U. S. dos
SOUZA, A. V. de
NUNES, C. E. P.
SALVADOR, M. J.
LORENZO, V. P.
QUINTANS JÚNIOR, L. J.
ALMEIDA, J. R. G. da S.
dc.subject.por.fl_str_mv Ansiedade
Dor
Insônia
Bioma Caatinga
Planta nativa
Quebra faca
Essential oil
Insomnia
Óleo essencial
Planta medicinal
Recurso natural
Anxiety
Pain
Medicinal plants
topic Ansiedade
Dor
Insônia
Bioma Caatinga
Planta nativa
Quebra faca
Essential oil
Insomnia
Óleo essencial
Planta medicinal
Recurso natural
Anxiety
Pain
Medicinal plants
description Ethnopharmacological relevance: Croton conduplicatus Kunth (Euphorbiaceae) is a Brazilian aromatic medicinal plant, widely known as ?quebra-faca?. In folk medicine, its leaves and stem-barks are used as a natural analgesic for the treatment of headaches. Aim of the study: In this study, we describe for the first time the neuropharmacological potential of the essential oil obtained from the leaves of Croton conduplicatus (EO) in experimental models of pain, anxiety and insomnia. The mechanisms of action involved in these activities were also investigated.
publishDate 2018
dc.date.none.fl_str_mv 2018-04-27T00:37:57Z
2018-04-27T00:37:57Z
2018-04-26
2018
2018-05-02T11:11:11Z
dc.type.driver.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Journal of Ethnopharmacology, v. 221, p. 65–76, 2018.
http://www.alice.cnptia.embrapa.br/alice/handle/doc/1090904
10.1016/j.jep.2018.04.009
identifier_str_mv Journal of Ethnopharmacology, v. 221, p. 65–76, 2018.
10.1016/j.jep.2018.04.009
url http://www.alice.cnptia.embrapa.br/alice/handle/doc/1090904
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron:EMBRAPA
instname_str Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
instacron_str EMBRAPA
institution EMBRAPA
reponame_str Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
collection Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)
repository.name.fl_str_mv Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)
repository.mail.fl_str_mv cg-riaa@embrapa.br
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