Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
Texto Completo: | http://www.alice.cnptia.embrapa.br/alice/handle/doc/1090904 |
Resumo: | Ethnopharmacological relevance: Croton conduplicatus Kunth (Euphorbiaceae) is a Brazilian aromatic medicinal plant, widely known as ?quebra-faca?. In folk medicine, its leaves and stem-barks are used as a natural analgesic for the treatment of headaches. Aim of the study: In this study, we describe for the first time the neuropharmacological potential of the essential oil obtained from the leaves of Croton conduplicatus (EO) in experimental models of pain, anxiety and insomnia. The mechanisms of action involved in these activities were also investigated. |
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Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved.AnsiedadeDorInsôniaBioma CaatingaPlanta nativaQuebra facaEssential oilInsomniaÓleo essencialPlanta medicinalRecurso naturalAnxietyPainMedicinal plantsEthnopharmacological relevance: Croton conduplicatus Kunth (Euphorbiaceae) is a Brazilian aromatic medicinal plant, widely known as ?quebra-faca?. In folk medicine, its leaves and stem-barks are used as a natural analgesic for the treatment of headaches. Aim of the study: In this study, we describe for the first time the neuropharmacological potential of the essential oil obtained from the leaves of Croton conduplicatus (EO) in experimental models of pain, anxiety and insomnia. The mechanisms of action involved in these activities were also investigated.RAIMUNDO GONÇALVES DE OLIVEIRA JÚNIOR, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; CHRISTIANE ADRIELLY ALVES FERRAZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; JULIANE CABRAL SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; ROXANA BRAGA DE ANDRADE TELES, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; MARIANA GAMA SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; TÂMARA COIMBRA DINIZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; UILIANE SOARES DOS SANTOS; ANA VALERIA VIEIRA DE SOUZA, CPATSA; CARLOS EDUARDO PEREIRA NUNES, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; MARCOS JOSÉ SALVADOR, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; VITOR PRATES LORENZO, Instituto Federal de Educação, Ciência e Tecnologia Sertão Pernambucano, Petrolina, PE; LUCINDO JOSÉ QUINTANS JÚNIOR, Departamento de Fisiologia, Universidade Federal de Sergipe (UFS), São Cristóvão, Sergipe; JACKSON ROBERTO GUEDES DA SILVA ALMEIDA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE.OLIVEIRA JÚNIOR, R. G. deFERRAZ, C. A. A.SILVA, J. C.TELES. R. B. de A.SILVA, M. G.DINIZ, T. C.SANTOS, U. S. dosSOUZA, A. V. deNUNES, C. E. P.SALVADOR, M. J.LORENZO, V. P.QUINTANS JÚNIOR, L. J.ALMEIDA, J. R. G. da S.2018-04-27T00:37:57Z2018-04-27T00:37:57Z2018-04-2620182018-05-02T11:11:11Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleJournal of Ethnopharmacology, v. 221, p. 65–76, 2018.http://www.alice.cnptia.embrapa.br/alice/handle/doc/109090410.1016/j.jep.2018.04.009enginfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice)instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa)instacron:EMBRAPA2018-04-27T00:38:04Zoai:www.alice.cnptia.embrapa.br:doc/1090904Repositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestopendoar:21542018-04-27T00:38:04falseRepositório InstitucionalPUBhttps://www.alice.cnptia.embrapa.br/oai/requestcg-riaa@embrapa.bropendoar:21542018-04-27T00:38:04Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa)false |
dc.title.none.fl_str_mv |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
title |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
spellingShingle |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. OLIVEIRA JÚNIOR, R. G. de Ansiedade Dor Insônia Bioma Caatinga Planta nativa Quebra faca Essential oil Insomnia Óleo essencial Planta medicinal Recurso natural Anxiety Pain Medicinal plants |
title_short |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
title_full |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
title_fullStr |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
title_full_unstemmed |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
title_sort |
Neuropharmacological effects of essential oil from the leaves of Croton conduplicatus Kunth and possible mechanisms of action involved. |
author |
OLIVEIRA JÚNIOR, R. G. de |
author_facet |
OLIVEIRA JÚNIOR, R. G. de FERRAZ, C. A. A. SILVA, J. C. TELES. R. B. de A. SILVA, M. G. DINIZ, T. C. SANTOS, U. S. dos SOUZA, A. V. de NUNES, C. E. P. SALVADOR, M. J. LORENZO, V. P. QUINTANS JÚNIOR, L. J. ALMEIDA, J. R. G. da S. |
author_role |
author |
author2 |
FERRAZ, C. A. A. SILVA, J. C. TELES. R. B. de A. SILVA, M. G. DINIZ, T. C. SANTOS, U. S. dos SOUZA, A. V. de NUNES, C. E. P. SALVADOR, M. J. LORENZO, V. P. QUINTANS JÚNIOR, L. J. ALMEIDA, J. R. G. da S. |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
RAIMUNDO GONÇALVES DE OLIVEIRA JÚNIOR, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; CHRISTIANE ADRIELLY ALVES FERRAZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; JULIANE CABRAL SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; ROXANA BRAGA DE ANDRADE TELES, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; MARIANA GAMA SILVA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; TÂMARA COIMBRA DINIZ, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE; UILIANE SOARES DOS SANTOS; ANA VALERIA VIEIRA DE SOUZA, CPATSA; CARLOS EDUARDO PEREIRA NUNES, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; MARCOS JOSÉ SALVADOR, Instituto de Biologia, Universidade Estadual de Campinas (UNICAMP), Campinas, SP; VITOR PRATES LORENZO, Instituto Federal de Educação, Ciência e Tecnologia Sertão Pernambucano, Petrolina, PE; LUCINDO JOSÉ QUINTANS JÚNIOR, Departamento de Fisiologia, Universidade Federal de Sergipe (UFS), São Cristóvão, Sergipe; JACKSON ROBERTO GUEDES DA SILVA ALMEIDA, Núcleo de Estudos e Pesquisas de Plantas Medicinais (NEPLAME), Universidade Federal do Vale do São Francisco (UNIVASF), Petrolina, PE. |
dc.contributor.author.fl_str_mv |
OLIVEIRA JÚNIOR, R. G. de FERRAZ, C. A. A. SILVA, J. C. TELES. R. B. de A. SILVA, M. G. DINIZ, T. C. SANTOS, U. S. dos SOUZA, A. V. de NUNES, C. E. P. SALVADOR, M. J. LORENZO, V. P. QUINTANS JÚNIOR, L. J. ALMEIDA, J. R. G. da S. |
dc.subject.por.fl_str_mv |
Ansiedade Dor Insônia Bioma Caatinga Planta nativa Quebra faca Essential oil Insomnia Óleo essencial Planta medicinal Recurso natural Anxiety Pain Medicinal plants |
topic |
Ansiedade Dor Insônia Bioma Caatinga Planta nativa Quebra faca Essential oil Insomnia Óleo essencial Planta medicinal Recurso natural Anxiety Pain Medicinal plants |
description |
Ethnopharmacological relevance: Croton conduplicatus Kunth (Euphorbiaceae) is a Brazilian aromatic medicinal plant, widely known as ?quebra-faca?. In folk medicine, its leaves and stem-barks are used as a natural analgesic for the treatment of headaches. Aim of the study: In this study, we describe for the first time the neuropharmacological potential of the essential oil obtained from the leaves of Croton conduplicatus (EO) in experimental models of pain, anxiety and insomnia. The mechanisms of action involved in these activities were also investigated. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-04-27T00:37:57Z 2018-04-27T00:37:57Z 2018-04-26 2018 2018-05-02T11:11:11Z |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/publishedVersion info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Journal of Ethnopharmacology, v. 221, p. 65–76, 2018. http://www.alice.cnptia.embrapa.br/alice/handle/doc/1090904 10.1016/j.jep.2018.04.009 |
identifier_str_mv |
Journal of Ethnopharmacology, v. 221, p. 65–76, 2018. 10.1016/j.jep.2018.04.009 |
url |
http://www.alice.cnptia.embrapa.br/alice/handle/doc/1090904 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
reponame:Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) instname:Empresa Brasileira de Pesquisa Agropecuária (Embrapa) instacron:EMBRAPA |
instname_str |
Empresa Brasileira de Pesquisa Agropecuária (Embrapa) |
instacron_str |
EMBRAPA |
institution |
EMBRAPA |
reponame_str |
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
collection |
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) |
repository.name.fl_str_mv |
Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA - Alice) - Empresa Brasileira de Pesquisa Agropecuária (Embrapa) |
repository.mail.fl_str_mv |
cg-riaa@embrapa.br |
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1794503452961800192 |