Cerebral Abscess with Cranial Hypertension in Young Infants: A Case Report and Systematic Review
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | MedNEXT Journal of Medical and Health Sciences |
Texto Completo: | https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/58 |
Resumo: | Objective: To report a Central Nervous System infection evolving with brain abscess and to address aspects of the treatment of the disease. Results: even with advances in treatment and diagnosis, the pathology has a high mortality. However, the best prognosis is noticed when there is a suspicion through the clinic, neuroradiological images readily available, antimicrobial therapy against commonly encountered agents, and surgical drainage procedures. One study, which combined antibiotic therapy and surgery to drain the abscess, in most of the cases, studied, demonstrated a mortality rate of 12%, and another study, a 42% mortality rate when using antibiotic therapy alone. Another reference suggests the use of antibiotic therapy alone in less severe cases with less neurological impairment. Neurological clinical sequelae can be found in up to 30% of cases. The time of antibiotic therapy still needs to be debated, as well as the surgical indication for drainage. Final Considerations: Pediatric brain abscess is an uncommon disease, still with high morbidity and mortality. Surgical drainage or excision of pediatric abscesses remains the basis of treatment both to relieve the mass effect and to provide a microbiological diagnosis. The literature demonstrates that broad-spectrum antibiotics and access to CT and MRI images decrease the rates of morbidity and mortality. It is concluded that the therapeutic approach involves the administration of broad-spectrum intravenous antibiotics and surgical drainage in more complex cases. |
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Cerebral Abscess with Cranial Hypertension in Young Infants: A Case Report and Systematic ReviewCerebral abscessIntracranial hypertensionPediatricsObjective: To report a Central Nervous System infection evolving with brain abscess and to address aspects of the treatment of the disease. Results: even with advances in treatment and diagnosis, the pathology has a high mortality. However, the best prognosis is noticed when there is a suspicion through the clinic, neuroradiological images readily available, antimicrobial therapy against commonly encountered agents, and surgical drainage procedures. One study, which combined antibiotic therapy and surgery to drain the abscess, in most of the cases, studied, demonstrated a mortality rate of 12%, and another study, a 42% mortality rate when using antibiotic therapy alone. Another reference suggests the use of antibiotic therapy alone in less severe cases with less neurological impairment. Neurological clinical sequelae can be found in up to 30% of cases. The time of antibiotic therapy still needs to be debated, as well as the surgical indication for drainage. Final Considerations: Pediatric brain abscess is an uncommon disease, still with high morbidity and mortality. Surgical drainage or excision of pediatric abscesses remains the basis of treatment both to relieve the mass effect and to provide a microbiological diagnosis. The literature demonstrates that broad-spectrum antibiotics and access to CT and MRI images decrease the rates of morbidity and mortality. It is concluded that the therapeutic approach involves the administration of broad-spectrum intravenous antibiotics and surgical drainage in more complex cases.Faceres2021-11-04info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionArticleapplication/pdfhttps://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/5810.54448/mdnt2141MedNEXT Journal of Medical and Health Sciences; Vol. 2 No. 4 (2021): MedNEXTMedNEXT Journal of Medical and Health Sciences; v. 2 n. 4 (2021): MedNEXT2763-567810.54448/mdnt214reponame:MedNEXT Journal of Medical and Health Sciencesinstname:Faculdade de Medicina em São José do Rio Preto (Faceres)instacron:FACERESenghttps://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/58/60Copyright (c) 2021 MedNEXT Journal of Medical and Health Scienceshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessMarqui, Náthalie Angélica CardosoLima, Marina Lucca de CamposBaptista, Rafaela de Fátima FerreiraRighetti, Rawene Elza Veronesi GonçalvesMartins, Tauane ReneMarconato, Gabrielle GomidesLeite, Gabriella CavalcanteViana, Kamila CristinaHauy, Beatriz NomadaModaelli, JaquelineMendes, Airton José2021-11-04T21:05:29Zoai:ojs2.mednext.zotarellifilhoscientificworks.com:article/58Revistahttps://mednext.zotarellifilhoscientificworks.com/index.php/mednextPUBhttps://mednext.zotarellifilhoscientificworks.com/index.php/mednext/oaimednextjmhs@zotarellifilhoscientificworks.com2763-56782763-5678opendoar:2021-11-04T21:05:29MedNEXT Journal of Medical and Health Sciences - Faculdade de Medicina em São José do Rio Preto (Faceres)false |
dc.title.none.fl_str_mv |
Cerebral Abscess with Cranial Hypertension in Young Infants: A Case Report and Systematic Review |
title |
Cerebral Abscess with Cranial Hypertension in Young Infants: A Case Report and Systematic Review |
spellingShingle |
Cerebral Abscess with Cranial Hypertension in Young Infants: A Case Report and Systematic Review Marqui, Náthalie Angélica Cardoso Cerebral abscess Intracranial hypertension Pediatrics |
title_short |
Cerebral Abscess with Cranial Hypertension in Young Infants: A Case Report and Systematic Review |
title_full |
Cerebral Abscess with Cranial Hypertension in Young Infants: A Case Report and Systematic Review |
title_fullStr |
Cerebral Abscess with Cranial Hypertension in Young Infants: A Case Report and Systematic Review |
title_full_unstemmed |
Cerebral Abscess with Cranial Hypertension in Young Infants: A Case Report and Systematic Review |
title_sort |
Cerebral Abscess with Cranial Hypertension in Young Infants: A Case Report and Systematic Review |
author |
Marqui, Náthalie Angélica Cardoso |
author_facet |
Marqui, Náthalie Angélica Cardoso Lima, Marina Lucca de Campos Baptista, Rafaela de Fátima Ferreira Righetti, Rawene Elza Veronesi Gonçalves Martins, Tauane Rene Marconato, Gabrielle Gomides Leite, Gabriella Cavalcante Viana, Kamila Cristina Hauy, Beatriz Nomada Modaelli, Jaqueline Mendes, Airton José |
author_role |
author |
author2 |
Lima, Marina Lucca de Campos Baptista, Rafaela de Fátima Ferreira Righetti, Rawene Elza Veronesi Gonçalves Martins, Tauane Rene Marconato, Gabrielle Gomides Leite, Gabriella Cavalcante Viana, Kamila Cristina Hauy, Beatriz Nomada Modaelli, Jaqueline Mendes, Airton José |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Marqui, Náthalie Angélica Cardoso Lima, Marina Lucca de Campos Baptista, Rafaela de Fátima Ferreira Righetti, Rawene Elza Veronesi Gonçalves Martins, Tauane Rene Marconato, Gabrielle Gomides Leite, Gabriella Cavalcante Viana, Kamila Cristina Hauy, Beatriz Nomada Modaelli, Jaqueline Mendes, Airton José |
dc.subject.por.fl_str_mv |
Cerebral abscess Intracranial hypertension Pediatrics |
topic |
Cerebral abscess Intracranial hypertension Pediatrics |
description |
Objective: To report a Central Nervous System infection evolving with brain abscess and to address aspects of the treatment of the disease. Results: even with advances in treatment and diagnosis, the pathology has a high mortality. However, the best prognosis is noticed when there is a suspicion through the clinic, neuroradiological images readily available, antimicrobial therapy against commonly encountered agents, and surgical drainage procedures. One study, which combined antibiotic therapy and surgery to drain the abscess, in most of the cases, studied, demonstrated a mortality rate of 12%, and another study, a 42% mortality rate when using antibiotic therapy alone. Another reference suggests the use of antibiotic therapy alone in less severe cases with less neurological impairment. Neurological clinical sequelae can be found in up to 30% of cases. The time of antibiotic therapy still needs to be debated, as well as the surgical indication for drainage. Final Considerations: Pediatric brain abscess is an uncommon disease, still with high morbidity and mortality. Surgical drainage or excision of pediatric abscesses remains the basis of treatment both to relieve the mass effect and to provide a microbiological diagnosis. The literature demonstrates that broad-spectrum antibiotics and access to CT and MRI images decrease the rates of morbidity and mortality. It is concluded that the therapeutic approach involves the administration of broad-spectrum intravenous antibiotics and surgical drainage in more complex cases. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-11-04 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/58 10.54448/mdnt2141 |
url |
https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/58 |
identifier_str_mv |
10.54448/mdnt2141 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://mednext.zotarellifilhoscientificworks.com/index.php/mednext/article/view/58/60 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2021 MedNEXT Journal of Medical and Health Sciences https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2021 MedNEXT Journal of Medical and Health Sciences https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Faceres |
publisher.none.fl_str_mv |
Faceres |
dc.source.none.fl_str_mv |
MedNEXT Journal of Medical and Health Sciences; Vol. 2 No. 4 (2021): MedNEXT MedNEXT Journal of Medical and Health Sciences; v. 2 n. 4 (2021): MedNEXT 2763-5678 10.54448/mdnt214 reponame:MedNEXT Journal of Medical and Health Sciences instname:Faculdade de Medicina em São José do Rio Preto (Faceres) instacron:FACERES |
instname_str |
Faculdade de Medicina em São José do Rio Preto (Faceres) |
instacron_str |
FACERES |
institution |
FACERES |
reponame_str |
MedNEXT Journal of Medical and Health Sciences |
collection |
MedNEXT Journal of Medical and Health Sciences |
repository.name.fl_str_mv |
MedNEXT Journal of Medical and Health Sciences - Faculdade de Medicina em São José do Rio Preto (Faceres) |
repository.mail.fl_str_mv |
mednextjmhs@zotarellifilhoscientificworks.com |
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