Antimicrobial activity of sesquiterpene lactones from yacon leaves (Smallanthus sonchifolius, Asteraceae)

Detalhes bibliográficos
Autor(a) principal: Vieira, Perla Raquel Nogueira
Data de Publicação: 2021
Outros Autores: Reis, Débora Raquel Mergen Lima, Oliveira, Cledes Teresinha de, souza, Carolina Ribeiro Noronha de
Tipo de documento: Artigo
Idioma: por
Título da fonte: Revista Fitos
Texto Completo: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/864
Resumo: Yacon (Smallanthus sonchifolius) is a native plant from the Andes belonging to the Asteraceae family. Its tubers and leaves are consumed mainly for the control of hyperglycemia. In addition, the glandular trichomes present in the leaves are rich in sesquiterpene lactones such as enyndrine, uvedalina and sonchifolin, which present antimicrobial activity against different strains of fungi and gram-positive bacteria. The antimicrobial activity of the sesquiterpene lactones extracted from leaves was evaluated against Candida albicans, Candida tropicalis, Staphylococcus aureus and Salmonella enterica Typhimurium by the disc diffusion method. Results show antimicrobial activity only against S. aureus. Minimum inhibitory concentration against S. aureus, calculated after the microdilution method, was 0.09 mg/ml. Results confirm the antimicrobial activity of sesquiterpene lactones against gram-positive bacteria.
id FIOCRUZ-1_a68e95bf77d212b6a90b4c03b7e78cb0
oai_identifier_str oai:ojs.revistafitos.far.fiocruz.br:article/864
network_acronym_str FIOCRUZ-1
network_name_str Revista Fitos
repository_id_str
spelling Antimicrobial activity of sesquiterpene lactones from yacon leaves (Smallanthus sonchifolius, Asteraceae)Atividade antimicrobiana das lactonas sesquiterpênicas da folha da yacon (Smallanthus sonchifolius, Asteraceae)Antimicrobial activityYaconSesquiterpene lactonesSmallanthus sonchifoliusAtividade antimicrobianaYaconLactonas sesquiterpênicasSmallanthus sonchifoliusYacon (Smallanthus sonchifolius) is a native plant from the Andes belonging to the Asteraceae family. Its tubers and leaves are consumed mainly for the control of hyperglycemia. In addition, the glandular trichomes present in the leaves are rich in sesquiterpene lactones such as enyndrine, uvedalina and sonchifolin, which present antimicrobial activity against different strains of fungi and gram-positive bacteria. The antimicrobial activity of the sesquiterpene lactones extracted from leaves was evaluated against Candida albicans, Candida tropicalis, Staphylococcus aureus and Salmonella enterica Typhimurium by the disc diffusion method. Results show antimicrobial activity only against S. aureus. Minimum inhibitory concentration against S. aureus, calculated after the microdilution method, was 0.09 mg/ml. Results confirm the antimicrobial activity of sesquiterpene lactones against gram-positive bacteria.A yacon (Smallanthus sonchifolius) é uma planta originária dos Andes pertencente à família Asteraceae. Seus tubérculos e folhas são consumidos de forma medicinal, principalmente para o controle da hiperglicemia. Adicionalmente, os tricomas glandulares presentes nas folhas são ricos em lactonas sesquiterpênicas (LST) como a enidrina, uvedalina e sonchifolina, que apresentam atividade antimicrobiana contra diferentes fungos e bactérias gram-positivas. No presente trabalho avaliou-se a atividade antimicrobiana das LST extraídas das folhas da yacon frente à cepas de Candida albicans, Candida tropicalis, Staphylococcus aureus e Salmonella enterica Typhimurium pelo método de difusão em disco. Encontrou-se atividade antimicrobiana contra S. aureus. Seguiu-se com o teste de microdiluição, que determinou uma concentração inibitória mínima de 0,09 mg/ml contra S. aureus. Os resultados confirmam o potencial antimicrobiano das lactonas sesquiterpênicas, especialmente contra bactérias gram-positivas.Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz2021-03-31info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdftext/htmltext/htmlhttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/86410.32712/2446-4775.2021.864Revista Fitos; Vol. 15 No. 1 (2021); 108-114Revista Fitos; Vol. 15 Núm. 1 (2021); 108-114Revista Fitos; v. 15 n. 1 (2021); 108-1142446-47751808-9569reponame:Revista Fitosinstname:Fundação Oswaldo Cruz (FIOCRUZ)instacron:FIOCRUZporhttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/864/765https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/864/766https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/864/829Copyright (c) 2021 Revista Fitoshttps://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessVieira, Perla Raquel NogueiraReis, Débora Raquel Mergen LimaOliveira, Cledes Teresinha desouza, Carolina Ribeiro Noronha de2021-05-14T13:48:27Zoai:ojs.revistafitos.far.fiocruz.br:article/864Revistahttps://revistafitos.far.fiocruz.br/index.php/revista-fitos/PUBhttp://revistafitos.far.fiocruz.br/index.php/revista-fitos/oairevistafitos@far.fiocruz.br || eugenio.telles@far.fiocruz.br2446-47752446-4775opendoar:2021-05-14T13:48:27Revista Fitos - Fundação Oswaldo Cruz (FIOCRUZ)false
dc.title.none.fl_str_mv Antimicrobial activity of sesquiterpene lactones from yacon leaves (Smallanthus sonchifolius, Asteraceae)
Atividade antimicrobiana das lactonas sesquiterpênicas da folha da yacon (Smallanthus sonchifolius, Asteraceae)
title Antimicrobial activity of sesquiterpene lactones from yacon leaves (Smallanthus sonchifolius, Asteraceae)
spellingShingle Antimicrobial activity of sesquiterpene lactones from yacon leaves (Smallanthus sonchifolius, Asteraceae)
Vieira, Perla Raquel Nogueira
Antimicrobial activity
Yacon
Sesquiterpene lactones
Smallanthus sonchifolius
Atividade antimicrobiana
Yacon
Lactonas sesquiterpênicas
Smallanthus sonchifolius
title_short Antimicrobial activity of sesquiterpene lactones from yacon leaves (Smallanthus sonchifolius, Asteraceae)
title_full Antimicrobial activity of sesquiterpene lactones from yacon leaves (Smallanthus sonchifolius, Asteraceae)
title_fullStr Antimicrobial activity of sesquiterpene lactones from yacon leaves (Smallanthus sonchifolius, Asteraceae)
title_full_unstemmed Antimicrobial activity of sesquiterpene lactones from yacon leaves (Smallanthus sonchifolius, Asteraceae)
title_sort Antimicrobial activity of sesquiterpene lactones from yacon leaves (Smallanthus sonchifolius, Asteraceae)
author Vieira, Perla Raquel Nogueira
author_facet Vieira, Perla Raquel Nogueira
Reis, Débora Raquel Mergen Lima
Oliveira, Cledes Teresinha de
souza, Carolina Ribeiro Noronha de
author_role author
author2 Reis, Débora Raquel Mergen Lima
Oliveira, Cledes Teresinha de
souza, Carolina Ribeiro Noronha de
author2_role author
author
author
dc.contributor.author.fl_str_mv Vieira, Perla Raquel Nogueira
Reis, Débora Raquel Mergen Lima
Oliveira, Cledes Teresinha de
souza, Carolina Ribeiro Noronha de
dc.subject.por.fl_str_mv Antimicrobial activity
Yacon
Sesquiterpene lactones
Smallanthus sonchifolius
Atividade antimicrobiana
Yacon
Lactonas sesquiterpênicas
Smallanthus sonchifolius
topic Antimicrobial activity
Yacon
Sesquiterpene lactones
Smallanthus sonchifolius
Atividade antimicrobiana
Yacon
Lactonas sesquiterpênicas
Smallanthus sonchifolius
description Yacon (Smallanthus sonchifolius) is a native plant from the Andes belonging to the Asteraceae family. Its tubers and leaves are consumed mainly for the control of hyperglycemia. In addition, the glandular trichomes present in the leaves are rich in sesquiterpene lactones such as enyndrine, uvedalina and sonchifolin, which present antimicrobial activity against different strains of fungi and gram-positive bacteria. The antimicrobial activity of the sesquiterpene lactones extracted from leaves was evaluated against Candida albicans, Candida tropicalis, Staphylococcus aureus and Salmonella enterica Typhimurium by the disc diffusion method. Results show antimicrobial activity only against S. aureus. Minimum inhibitory concentration against S. aureus, calculated after the microdilution method, was 0.09 mg/ml. Results confirm the antimicrobial activity of sesquiterpene lactones against gram-positive bacteria.
publishDate 2021
dc.date.none.fl_str_mv 2021-03-31
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/864
10.32712/2446-4775.2021.864
url https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/864
identifier_str_mv 10.32712/2446-4775.2021.864
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/864/765
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/864/766
https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/864/829
dc.rights.driver.fl_str_mv Copyright (c) 2021 Revista Fitos
https://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2021 Revista Fitos
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
text/html
dc.publisher.none.fl_str_mv Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz
publisher.none.fl_str_mv Centro de Inovação em Biodiversidade e Saúde - Farmanguinhos/Fiocruz
dc.source.none.fl_str_mv Revista Fitos; Vol. 15 No. 1 (2021); 108-114
Revista Fitos; Vol. 15 Núm. 1 (2021); 108-114
Revista Fitos; v. 15 n. 1 (2021); 108-114
2446-4775
1808-9569
reponame:Revista Fitos
instname:Fundação Oswaldo Cruz (FIOCRUZ)
instacron:FIOCRUZ
instname_str Fundação Oswaldo Cruz (FIOCRUZ)
instacron_str FIOCRUZ
institution FIOCRUZ
reponame_str Revista Fitos
collection Revista Fitos
repository.name.fl_str_mv Revista Fitos - Fundação Oswaldo Cruz (FIOCRUZ)
repository.mail.fl_str_mv revistafitos@far.fiocruz.br || eugenio.telles@far.fiocruz.br
_version_ 1798313475048472576

Registros relacionados