Variation of the physico-chemical properties of extracts of Bidens pilosa L. Asteraceae (hairy beggartick) influenced by the extractive process

• Autor(a) principal: Borella, Júlio Cézar
• Data de Publicação: 2023
• Outros Autores: Oliveira, Bianca de Fátima Bredariol
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Revista Fitos
• Texto Completo: https://revistafitos.far.fiocruz.br/index.php/revista-fitos/article/view/1353
• topic: Fitoterapia; Medicamentos fitoterápicos; Extratos vegetais; Phytotherapy; Phytotherapeutic Drugs; Plant Extracts

In order to provide the basis for the introduction of a larger number of plant species and their derivatives in the national pharmaceutical compendia, physicochemical, chromatographic and quantitative analyzes of the marker were performed in extracts obtained from Bidens pilosa L. Asteraceae (hairy beggartick) aerial parts, species with antioxidant, antibacterial, anti-inflammatory, antitumor, antimalarial, immunomodulatory, hepatoprotective, healing activities, among others. From hydroethanolic (EtOH: H2O 77:23), hydroglycolic (PEG:H2O 1:1) and aqueous extracts obtained by maceration (1:10), the density, pH, solid content, chromatographic profile (TLC) and total flavonoid content (spectrophotometry) were evaluated. The analyzes showed that the highest density extracts were aqueous (0.9595 g / mL) and hydroglycolic (1.0418 g / mL). Hydroglycolic (pH = 6.32) and hydroethanolic (pH = 6.29) extracts showed more acids than aqueous ones (pH = 6.95). Higher dry residues were presented by hydroethanolic (2.40%) and hydroglycolic (2.70%) extracts compared to aqueous (0.53%). Quercetin was identified by TLC in all extracts tested and greater diversity of substances was evidenced in hydroethanolic and hydroglycolic extracts. Higher flavonoid contents were found in hydroethanolic and hydroglycolic extracts (0.009%; 0.008% respectively) than in aqueous extracts (0.003%). In spite of this, the aqueous extracts are more selectively extracted for the researched marker.