Primary resistance of human immunodeficiency virus type 1 in a reference center in Recife, Pernambuco, Brazil

Detalhes bibliográficos
Autor(a) principal: Medeiros,Luzidalva Barbosa de
Data de Publicação: 2006
Outros Autores: Lacerda,Heloísa Ramos, Cavalcanti,Ana Maria Salustiano, Albuquerque,Maria de Fátima Pessoa Militão de
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Memórias do Instituto Oswaldo Cruz
Texto Completo: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000800004
Resumo: To assess the prevalence of primary resistance of human immunodeficiency virus type 1 (HIV-1) to antiretrovirals, 84 patients chronically infected with HIV without prior antiretroviral treatment from Northeast Brazil were studied. Genotyping was performed using the ViroSeqTM Genotyping System. Thimidine analog mutations occurred in 3 (3.6%) patients. Accessory mutations related to NRTI occurred in 6 (7.1%) and related to PI in 67 (79.8%). Subtypes B (72.6%), F (22.6%), B/F 3 (3.6%), and C (1.2%) were detected. A low prevalence of major mutations related to NRTI in patients chronically infected by HIV was observed.
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spelling Primary resistance of human immunodeficiency virus type 1 in a reference center in Recife, Pernambuco, Brazilhuman imunodeficiency virus type 1primary resistance to drugsgenotypingsubtypesBrazilTo assess the prevalence of primary resistance of human immunodeficiency virus type 1 (HIV-1) to antiretrovirals, 84 patients chronically infected with HIV without prior antiretroviral treatment from Northeast Brazil were studied. Genotyping was performed using the ViroSeqTM Genotyping System. Thimidine analog mutations occurred in 3 (3.6%) patients. Accessory mutations related to NRTI occurred in 6 (7.1%) and related to PI in 67 (79.8%). Subtypes B (72.6%), F (22.6%), B/F 3 (3.6%), and C (1.2%) were detected. A low prevalence of major mutations related to NRTI in patients chronically infected by HIV was observed.Instituto Oswaldo Cruz, Ministério da Saúde2006-12-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000800004Memórias do Instituto Oswaldo Cruz v.101 n.8 2006reponame:Memórias do Instituto Oswaldo Cruzinstname:Fundação Oswaldo Cruzinstacron:FIOCRUZ10.1590/S0074-02762006000800004info:eu-repo/semantics/openAccessMedeiros,Luzidalva Barbosa deLacerda,Heloísa RamosCavalcanti,Ana Maria SalustianoAlbuquerque,Maria de Fátima Pessoa Militão deeng2020-04-25T17:49:40Zhttp://www.scielo.br/oai/scielo-oai.php0074-02761678-8060opendoar:null2020-04-26 02:14:02.868Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruztrue
dc.title.none.fl_str_mv Primary resistance of human immunodeficiency virus type 1 in a reference center in Recife, Pernambuco, Brazil
title Primary resistance of human immunodeficiency virus type 1 in a reference center in Recife, Pernambuco, Brazil
spellingShingle Primary resistance of human immunodeficiency virus type 1 in a reference center in Recife, Pernambuco, Brazil
Medeiros,Luzidalva Barbosa de
human imunodeficiency virus type 1
primary resistance to drugs
genotyping
subtypes
Brazil
title_short Primary resistance of human immunodeficiency virus type 1 in a reference center in Recife, Pernambuco, Brazil
title_full Primary resistance of human immunodeficiency virus type 1 in a reference center in Recife, Pernambuco, Brazil
title_fullStr Primary resistance of human immunodeficiency virus type 1 in a reference center in Recife, Pernambuco, Brazil
title_full_unstemmed Primary resistance of human immunodeficiency virus type 1 in a reference center in Recife, Pernambuco, Brazil
title_sort Primary resistance of human immunodeficiency virus type 1 in a reference center in Recife, Pernambuco, Brazil
author Medeiros,Luzidalva Barbosa de
author_facet Medeiros,Luzidalva Barbosa de
Lacerda,Heloísa Ramos
Cavalcanti,Ana Maria Salustiano
Albuquerque,Maria de Fátima Pessoa Militão de
author_role author
author2 Lacerda,Heloísa Ramos
Cavalcanti,Ana Maria Salustiano
Albuquerque,Maria de Fátima Pessoa Militão de
author2_role author
author
author
dc.contributor.author.fl_str_mv Medeiros,Luzidalva Barbosa de
Lacerda,Heloísa Ramos
Cavalcanti,Ana Maria Salustiano
Albuquerque,Maria de Fátima Pessoa Militão de
dc.subject.por.fl_str_mv human imunodeficiency virus type 1
primary resistance to drugs
genotyping
subtypes
Brazil
topic human imunodeficiency virus type 1
primary resistance to drugs
genotyping
subtypes
Brazil
dc.description.none.fl_txt_mv To assess the prevalence of primary resistance of human immunodeficiency virus type 1 (HIV-1) to antiretrovirals, 84 patients chronically infected with HIV without prior antiretroviral treatment from Northeast Brazil were studied. Genotyping was performed using the ViroSeqTM Genotyping System. Thimidine analog mutations occurred in 3 (3.6%) patients. Accessory mutations related to NRTI occurred in 6 (7.1%) and related to PI in 67 (79.8%). Subtypes B (72.6%), F (22.6%), B/F 3 (3.6%), and C (1.2%) were detected. A low prevalence of major mutations related to NRTI in patients chronically infected by HIV was observed.
description To assess the prevalence of primary resistance of human immunodeficiency virus type 1 (HIV-1) to antiretrovirals, 84 patients chronically infected with HIV without prior antiretroviral treatment from Northeast Brazil were studied. Genotyping was performed using the ViroSeqTM Genotyping System. Thimidine analog mutations occurred in 3 (3.6%) patients. Accessory mutations related to NRTI occurred in 6 (7.1%) and related to PI in 67 (79.8%). Subtypes B (72.6%), F (22.6%), B/F 3 (3.6%), and C (1.2%) were detected. A low prevalence of major mutations related to NRTI in patients chronically infected by HIV was observed.
publishDate 2006
dc.date.none.fl_str_mv 2006-12-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000800004
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000800004
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0074-02762006000800004
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
publisher.none.fl_str_mv Instituto Oswaldo Cruz, Ministério da Saúde
dc.source.none.fl_str_mv Memórias do Instituto Oswaldo Cruz v.101 n.8 2006
reponame:Memórias do Instituto Oswaldo Cruz
instname:Fundação Oswaldo Cruz
instacron:FIOCRUZ
reponame_str Memórias do Instituto Oswaldo Cruz
collection Memórias do Instituto Oswaldo Cruz
instname_str Fundação Oswaldo Cruz
instacron_str FIOCRUZ
institution FIOCRUZ
repository.name.fl_str_mv Memórias do Instituto Oswaldo Cruz - Fundação Oswaldo Cruz
repository.mail.fl_str_mv
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